Results 81 to 90 of about 116,778 (380)

Novel compound heterozygous variants in the PCCB gene causing adult-onset propionic acidemia presenting with neuropsychiatric symptoms: a case report and literature review

BMC Medical Genomics, 2022
Background Propionic acidemia (PA) is a rare autosomal recessive disorder of metabolism caused by mutations in the PCCA or PCCB gene, leading to propionyl CoA carboxylase (PCC) enzyme deficiencies.
Yingxuan Li, Miaomiao Wang, Zhaoyang Huang, Jing Ye, Yuping Wang   +4 more
doaj   +1 more source

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

Advanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee, Sojin Kim, Myeongeun Lee, Kyoungsuk Jin, Jimin Park   +4 more
wiley   +1 more source

Noninvasive Brain Stimulation and Personal Identity: Ethical Considerations. [PDF]

, 2017
As noninvasive brain stimulation (NIBS) technology advances, these methods may become increasingly capable of influencing complex networks of mental functioning. We suggest that these might include cognitive and affective processes underlying personality
Iwry, Jonathan, Newberg, Andrew B., Yaden, David B.   +2 more
core   +3 more sources

cpCST: a new continuous performance test for high-precision assessment of attention across the lifespan

Frontiers in Psychology
IntroductionAssessing sustained attention presents methodological challenges, particularly when spanning diverse populations whose baseline sensorimotor functioning may vary significantly.MethodsThis study introduces the Continuous Performance Critical ...
Anna MacKay-Brandt, Daniel Garcia-Barnett, Kai Xuan Gan, Olivia Ripley, Elaine Gazes, Michael Milham, Michael Milham, Stan Colcombe, Stan Colcombe, Stan Colcombe, Stan Colcombe   +10 more
doaj   +1 more source

Neuron matters: neuromodulation with electromagnetic stimulation must consider neurons as dynamic identities

Journal of NeuroEngineering and Rehabilitation, 2022
Neuromodulation with electromagnetic stimulation is widely used for the control of abnormal neural activity, and has been proven to be a valuable alternative to pharmacological tools for the treatment of many neurological diseases.
H. Ye, Jenna Hendee, Joyce Ruan, Alena Zhirova, Jayden Ye, Maria Dima   +5 more
semanticscholar   +1 more source

Astrocyte‐Guided Maturation of Neural Constructs in a Modular Biosynthetic Hydrogel for Biohybrid Neurotechnologies

Advanced Functional Materials, EarlyView.
A modular biosynthetic PVA–gelatin hydrogel crosslinked via visible‐light thiol‐ene chemistry is engineered as a coating for neural electrodes. Optimizing matrix composition and mechanical properties enables the hydrogel to support astrocytic populations that guide neural differentiation and functional maturation.
Martina Genta, Sofia Peressotti, Roberto Portillo‐Lara, Josef Goding, Rylie Green   +4 more
wiley   +1 more source

Antiarrhythmic and proarrhythmic effects of subcutaneous nerve stimulation in ambulatory dogs [PDF]

, 2019
Background High output subcutaneous nerve stimulation (ScNS) remodels the stellate ganglia and suppresses cardiac arrhythmia. Objective To test the hypothesis that long duration low output ScNS causes cardiac nerve sprouting, increases plasma ...
Chen, Mu, Chen, Peng-Sheng, Chen, Zhenhui, Everett, Thomas H., IV, Fishbein, Michael C., Grant, Maria B., Shen, Changyu, Wan, Juyi, Wang, Zhuo, Wong, Johnson, Yuan, Yuan   +10 more
core   +1 more source

Neuromodulation with nanoparticles [PDF]

Science, 2017
Ultrasonic drug uncaging shows potential for noninvasive manipulation of the ...
openaire   +2 more sources

From In‐Silico Optimized Microfabrication to Experimental Validation: Engineering a Tridimensional Epi‐Intraneural Interface

Advanced Functional Materials, EarlyView.
An epi‐intraneural interface is developed through in silico optimization and a novel tridimensional microfabrication pipeline. The device integrates penetrating and epineural contacts on a flexible substrate. Mechanical, electrochemical, and in vivo testing in rat and pig reveal robust implantation, low‐threshold activation, and site‐dependent ...
Federico Ciotti, Andrea Cimolato, Noemi Gozzi, Pietro Palopoli, Luca Brugnoli, Natalija Katic Secerovic, Rebecca Gallivan, Alexander Shokurov, Carlo Menon, Johannes Weichart, Ignacio Delgado‐Martinez, Weiguo Song, Stavros Zanos, Xavier Navarro, Stanisa Raspopovic   +14 more
wiley   +1 more source

Microvascular decompression or neuromodulation in patients with SUNCT and trigeminal neurovascular conflict? [PDF]

, 2017
Objectives To assess the effectiveness of neuromodulation and trigeminal microvascular decompression (MVD) in patients with medically-intractable short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT ...
Hassan, S, Lagrata, S, Levy, A, Matharu, M, Zrinzo, L   +4 more
core   +1 more source