Results 1 to 10 of about 27,995 (224)
Skin hypersensitivity in chronic cough patients: symptom profiles and psychosomatic correlates [PDF]
Annals of MedicineBackground Cough hypersensitivity syndrome (CHS) is a characteristic of patients with chronic cough (CC). Sensitive skin syndrome (SSS), which is characterised by cutaneous pain and pruritus, may share neural hypersensitivity mechanisms with CHS.
Tongyangzi Zhang +11 more
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A PKA activity sensor for quantitative analysis of endogenous GPCR signaling via 2-photon FRET-FLIM imaging [PDF]
Frontiers in Pharmacology, 2014 Neuromodulators have profound effects on behavior, but the dynamics of their intracellular effectors has remained unclear. Most neuromodulators exert their function via G-protein-coupled receptors (GPCRs).
Yao eChen +6 more
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Exploration of the potential neurotransmitter or neuromodulator-like properties of harmine: evidence from synthesis to synaptic modulation [PDF]
Frontiers in PharmacologyBackground:The discovery of new neurotransmitters is crucial for the in-depth understanding of neural signal transmission, neurological disorders, and relevant treatment strategies.
Zhejun Xie +6 more
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Emotional words evoke region- and valence-specific patterns of concurrent neuromodulator release in human thalamus and cortex [PDF]
Cell ReportsSummary: Words represent a uniquely human information channel—humans use words to express thoughts and feelings and to assign emotional valence to experience.
Seth R. Batten +20 more
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Frontiers in Psychiatry, 2022 Background and objectiveLong-course (LC) antidepressants for the treatment of disorders of gut-brain interaction, such as refractory functional dyspepsia (rFD), pose patients at risk of antidepressant discontinuation syndrome (ADS).
Qian-Qian Wang +7 more
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Advanced Electronic Materials, 2023 Artificial optoelectronic synapses with flexibly regulated synaptic weight are crucial to the rapidly evolved artificial visual system. Although three‐terminal devices with transistor geometry have exhibited controllable synaptic response through ...
Xun Han +11 more
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PLoS Biology, 2020 Ca2+/calmodulin-dependent kinase II (CaMKII) regulates synaptic plasticity in multiple ways, supposedly including the secretion of neuromodulators like brain-derived neurotrophic factor (BDNF).
Alessandro Moro +3 more
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Astrocytes—The Ultimate Effectors of Long-Range Neuromodulatory Networks?
Frontiers in Cellular Neuroscience, 2020 It was long thought that astrocytes, given their lack of electrical signaling, were not involved in communication with neurons. However, we now know that one astrocyte on average maintains and regulates the extracellular neurotransmitter and potassium ...
Anthony G. Pacholko +2 more
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Animals, 2021 Assistance dogs must manage stress efficiently because they are involved in challenging tasks. Their welfare is currently a fundamental issue. This preliminary study aimed to compare assistance dogs (AD; n = 22) with pet dogs (PD; n = 24), using blood ...
Manuel Mengoli +8 more
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Neuromodulation using electroosmosis
Journal of Neural Engineering, 2021 Abstract Objective. Our laboratory has proposed chemical stimulation of retinal neurons using exogenous glutamate as a biomimetic strategy for treating vision loss caused by photoreceptor (PR) degenerative diseases.
Sai Siva Kare +4 more
openaire +3 more sources