Results 91 to 100 of about 27,995 (224)

A Cognitive Architecture for the Implementation of Emotions in Computing Systems

open access: yes, 2016
In this paper we present a new neurobiologically-inspired affective cognitive architecture: NEUCOGAR (NEUromodulating COGnitive ARchitecture). The objective of NEUCOGAR is the identification of a mapping from the influence of serotonin, dopamine and ...
Distefano, Salvatore   +5 more
core   +1 more source

ATP as a presynaptic modulator [PDF]

open access: yes, 2000
© 2000 Elsevier Science Inc.There is considerable evidence that ATP acts as a fast transmitter or co-transmitter in autonomic and sensory nerves mostly through activation of ionotropic P2X receptors but also through metabotropic P2Y receptors. By analogy,
Cunha, Rodrigo A., Ribeiro, J. A.
core   +1 more source

Adaptation of Enhanced Recovery After Surgery Protocol for Elective Gastrointestinal and Hepatopancreaticobiliary Surgeries for Tertiary Hospitals in Ethiopia: A Modified Delphi Study

open access: yesWorld Journal of Surgery, EarlyView.
This adapted protocol consisting of 27 recommendations represents a critical step toward implementing standardized resource‐appropriate ERAS pathways for GI and HPB surgeries in Ethiopia. ABSTRACT Background Patients in low‐ and middle‐income countries (LMICs) lack access to safe and affordable surgical and anesthetic care.
Wongel Tena Shale   +7 more
wiley   +1 more source

Editorial: Stress Induced Neural Changes in Emotional Disorders

open access: yesFrontiers in Psychiatry, 2021
Fushun Wang   +4 more
doaj   +1 more source

Dopaminergic Regulation of Neuronal Circuits in Prefrontal Cortex [PDF]

open access: yes, 2001
Neuromodulators, like dopamine, have considerable influence on the\ud processing capabilities of neural networks. \ud This has for instance been shown in the working memory functions\ud of prefrontal cortex, which may be regulated by altering the\ud ...
Scheler, Gabriele
core  

Structure-function relationships in human D-amino acid oxidase. [PDF]

open access: yes, 2015
5Since D-amino acids were identified in mammals, D-serine has been one of the most extensively studied ‘‘unnatural amino acids’’. This brain-enriched transmitterlike molecule plays a pivotal role in the human central nervous system by modulating the ...

core   +1 more source

Novel Symptom Subgroups in Patients With Irritable Bowel Syndrome Are Associated With Healthcare Utilisation in Secondary and Tertiary Care

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In patients with IBS in secondary and tertiary care, latent class analysis model identified groups of individuals with more severe symptoms and greater impairments in quality of life at baseline and significantly higher rates of healthcare utilisation during longitudinal follow‐up. ABSTRACT Background & Aims Current classification systems for irritable
Vivek C. Goodoory   +12 more
wiley   +1 more source

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

open access: yesBritish Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman   +3 more
wiley   +1 more source

Instabilities of the cortex during natural sleep [PDF]

open access: yes, 2005
The electrical signals generated by the human cortex during sleep have been widely studied over the last 50 years. The electroencephalogram (EEG) observed during natural sleep exhibits structures with frequencies from 0.5 Hz to over 50 Hz and complicated
Sleigh, James W.   +3 more
core  

CXCL12/CXCR4 axis: an emerging neuromodulator in pathological pain [PDF]

open access: yes, 2016
The roles of chemokine C-X-C motif ligand 12 (CXCL12) and its receptor chemokine C-X-C motif receptor 4 (CXCR4) reveal this chemokine axis as an emerging neuromodulator in the nervous system. In the peripheral and central nervous systems, both CXCL12 and
Cheung, CW   +4 more
core   +1 more source

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