Results 11 to 20 of about 27,995 (224)

State-Dependent and -Independent Effects of Dialyzing Excitatory Neuromodulator Receptor Antagonists into the Ventral Respiratory Column [PDF]

open access: yes, 2017
Unilateral dialysis of the broad-spectrum muscarinic receptor antagonist atropine (50 mM) into the ventral respiratory column [(VRC) including the pre-Bötzinger complex region] of awake goats increased pulmonary ventilation (V̇i) and breathing frequency (
Burgraff, Nicholas J.   +7 more
core   +2 more sources

Corelease of acetylcholine and GABA from cholinergic forebrain neurons

open access: yeseLife, 2015
Neurotransmitter corelease is emerging as a common theme of central neuromodulatory systems. Though corelease of glutamate or GABA with acetylcholine has been reported within the cholinergic system, the full extent is unknown.
Arpiar Saunders   +2 more
doaj   +1 more source

Personalizing neuromodulation

open access: yesInternational Journal of Psychophysiology, 2020
In the era of "big data", we are gaining rich person-specific information about neuroanatomy, neural function, and cognitive functions. However, the optimal ways to create precise approaches to optimize individuals' mental functions in health and disease are unclear.
John D. Medaglia   +3 more
openaire   +3 more sources

Sensory Neuromodulation [PDF]

open access: yesFrontiers in Systems Neuroscience, 2018
We describe a model of neurological disease based on dysfunctional brain oscillators.  This is not a new model, but it is not one that is generally appreciated by clinicians.  The value of this model lies in the predictions it makes and the utility it provides in translational applications, in particular for neuromodulation devices ...
Black, Robert D., Rogers, Lesco L.
openaire   +3 more sources

Evidence for Respiratory Neuromodulator Interdependence after Cholinergic Disruption in the Ventral Respiratory Column [PDF]

open access: yes, 2015
Reverse dialysis of the muscarinic receptor antagonist, atropine (ATR, 50 mM), into the pre-Bötzinger Complex region of the ventral respiratory column (VRC) of awake and sleeping goats increases breathing frequency and serotonin (5-HT), substance P (SP),
Forster, Hubert   +6 more
core   +2 more sources

Neuromodulation [PDF]

open access: yesUS Neurology, 2016
Neuromodulation is a new promising treatment for headache disorders. It consists of peripheral nerve neurostimulation and central neurostimulation.
David W. Dodick, Stephen D. Silberstein
  +4 more sources

A continuum model for the dynamics of the phase transition from slow-wave sleep to REM sleep [PDF]

open access: yes, 2010
Previous studies have shown that activated cortical states (awake and rapid eye-movement (REM) sleep), are associated with increased cholinergic input into the cerebral cortex.
Li, Xiaoli   +5 more
core   +2 more sources

Remission of social behavior impairment by oral administration of a precursor of NAD in CD157, but not in CD38, knockout mice

open access: yesFrontiers in Immunology, 2023
Nicotinamide adenine dinucleotide (NAD) is a substrate of adenosine diphosphate (ADP)-ribosyl cyclase and is catalyzed to cyclic ADP-ribose (cADPR) by CD38 and/or CD157.
Maria Gerasimenko, Haruhiro Higashida
doaj   +1 more source

Combined Unilateral Blockade of Cholinergic, Peptidergic, And Serotonergic Receptors in The Ventral Respiratory Column Does Not Affect Breathing in Awake Or Sleeping Goats [PDF]

open access: yes, 2015
Previous work in intact awake and sleeping goats has found that unilateral blockade of excitatory inputs in the ventral respiratory column (VRC) elicits changes in the concentrations of multiple neurochemicals, including serotonin (5-HT), substance P ...
Forster, Hubert   +7 more
core   +2 more sources

Escape steering by cholecystokinin peptidergic signaling

open access: yesCell Reports, 2022
Summary: Escape is an evolutionarily conserved and essential avoidance response. Considered to be innate, most studies on escape responses focused on hard-wired circuits.
Lili Chen   +15 more
doaj   +1 more source

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