Results 41 to 50 of about 24,188 (302)

Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries [PDF]

, 2016
IMPORTANCE: Limited information exists about the epidemiology, recognition, management, and outcomes of patients with the acute respiratory distress syndrome (ARDS).
Alejandro, Risso V., Alvarez, Javier, Bellani, Giacomo, Bettini, Lisandro R., Bisso, Mariano Carboni, Brochard, Laurent, Cani, Alma, Cardonnet, Luis P., Chena, Ariel, Conti, Sara, Daldin, Julio, Dellera, Christian, Esteban, Andres, Estenssoro, Elisa, Fan, Eddy, Fernandez, Ruben O., Francois, Guy M., Gattinoni, Luciano, Grubissich, Nicolas, Ilutovich, Santiago, Insaurralde, Carolina S., Laffey, John G., Larsson, Anders, Lovazzano, Pablo, Madotto, Fabiana, McAuley, Daniel F., Nunci, Lordian, Osman, Emilio M., Pellegrini, Carlos A., Pesenti, Antonio, Pham, Tài, Plotnikow, Gustavo A., Pozo, Norberto C., Rabboni, Francesca, Ranieri, Marco, Rubenfeld, Gordon, Saenz, María G., Schultz, Marcus J., Setten, Mariano G., Simonis, Fabienne D., Slutsky, Arthur S., Sula, Hektor, Thompson, B. Taylor, Tiribelli, Norberto, van Haren, Frank, Vasquez, Daniela N., Villar, Veronica, Vinzio, Mauricio, Wrigge, Hermann, Zazu, Alan   +49 more
core   +3 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Influência da nifedipina no bloqueio neuromuscular produzido pelo atracúrio e pelo cisatracúrio: estudo em preparações nervo frênico-diafragma de rato Influencia de la nifedipina en el bloqueo neuromuscular producido por atracurio y cisatracurio: estudio en preparación nervio frénico diafragma de ratón Influence of nifedipine on the neuromuscular block produced by atracurium and cistracurium: study in rat phrenic-diaphragmatic nerve preparation

Revista Brasileira de Anestesiologia, 2006
JUSTIFICATIVA E OBJETIVOS: Os bloqueadores de canais de cálcio podem interagir com bloqueadores neuromusculares potencializando seus efeitos. Os estudos sobre essa interação mostram resultados controversos.
Silmara Rodrigues de Sousa, Angélica de Fátima de Assunção Braga, Glória Maria Braga Potério, Franklin Sarmento da Silva Braga, Yolanda Christina S Loyola, Samanta Cristina Antoniassi Fernandes   +5 more
doaj   +1 more source

Effect of Priming Dose Rocuronium Use on Intubation Quality and Duration

İstanbul Medical Journal, 2023
Introduction: This study aimed to investigate the effects of priming dose application with rocuronium, considering ideal body weight (IBW), on intubation quality and duration during the use of rocuronium and vecuronium as neuromuscular blockers. Methods:
Özlem Ateşal, Abdurrahman Tünay, Sinan Uzman   +2 more
doaj   +1 more source

Cromakalim (BRL 34915) restores in vitro the membrane potential of depolarized human skeletal muscle fibres [PDF]

, 1989
The purpose of the present study was to analyze the effects of cromakalim (BRL 34915), a potent drug from a new class of drugs characterized as K+ channel openers, on the electrical activity of human skeletal muscle.
Grafe, Peter, Lehmann-Horn, Frank, Spuler, A.   +2 more
core   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source

Evaluation of the three different doses of cisatracurium during general anaesthesia: A prospective randomized study

Journal of Anaesthesiology Clinical Pharmacology
Background and Aims: The present study was conducted to determine the optimal dose of cisatracurium for intubating conditions and onset and offset of neuromuscular blockade.
Prashant Kumar, Jyoti Vats, Kiranpreet Kaur, Jyoti Sharma, Sanjay Johar   +4 more
doaj   +1 more source

Potentiation Effects of Acetylcholine at Neuromuscular Junction by Ranitidine

Journal of Islamic International Medical College, 2021
Objective: To evaluate the activity of Ranitidine at neuromuscular junction with and without Pancuronium. Study Design: Experimental randomized control study.
Abdul Azeem , Akbar Waheed , Sidra Mumal , Salman Bakhtiar , Jawaria Iftikhar , Talal Zafar
doaj  

Influência do lítio no bloqueio neuromuscular produzido pelo atracúrio e pelo cisatracúrio: estudo em preparações nervo frênico-diafragma de rato Influencia del litio en el bloqueo neuromuscular producido por el atracurio y por el cisatracurio: estudio en preparo nervio frénico-diafragma del ratón Influence of lithium on the neuromuscular blockade produced by atracurium and cisatracurium: study on rat phrenic nerve-diaphragm preparations

Revista Brasileira de Anestesiologia, 2007
JUSTIFICATIVA E OBJETIVOS: O lítio, fármaco amplamente utilizado nos distúrbios bipolares, pode interagir com os bloqueadores neuromusculares. Os mecanismos para explicar os seus efeitos na transmissão neuromuscular e a interação com bloqueadores ...
Samanta Cristina Antoniassi Fernandes, Angélica de Fátima de Assunção Braga, Franklin Sarmento da Silva Braga, Yolanda Christina S. Loyola, Silmara Rodrigues de Souza, Caroline Coutinho de Barcelos   +5 more
doaj   +1 more source

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce, Goknur Selen Kocak, José Verdú‐Díaz, Jorge Alonso‐Pérez, Kristl G. Claeys, Tanya Stojkovic, Gorka Fernández‐Eulate, Pascal Laforêt, Najoua Miladi, Filipe Di Pace, Cristiane Araujo Martins Moreno, Edmar Zanoteli, Conrad C. Weihl, Volker Straub, Ana Töpf, Jordi Díaz‐Manera, Sarcoglycan European Cohort Consortium, Adele D′Amico, Adolfo López de Munain, Alicia Alonso‐Jiménez, Ana Camacho‐Salas, Andrea Gangfuß, Andrés Nascimento, Anna Sarkozy, Anneke J. van der Kooi, Arturo Fraga‐Bau, Béla Melegh, Benedikt Schoser, Bjarne Udd, Blaz Koritnik, Carlos Ortez, Chiara Marini Bettolo, Chiara Panicucci, Claudia Weiss, Claudio Bruno, Claudio Semplicini, Cristina Dominguez‐González, Cristina Garrido, David Gómez‐Andrés, Edoardo Malfatti, Elena Pegoraro, Elke De Vos, Francina Munell, Gabriele Dekomien, Giacomo Pietro Comi, Giorgio Tasca, Isabelle Richard, Jan L. De Bleecker, Jana Haberlová, Jesper Helbo Storgaard, Johanna Palmio, John Vissing, Juan Carlos de Leon‐Hernández, Kinga Hadzsiev, Laura Costa‐Comellas, Lea Leonardis, Leroy ten Dam, Lidia González‐Quereda, Luca Bello, Luisa Politano, Manuela Santos, Marianne de Visser, Marie Rohlenová, Matteo Garibaldi, Michela Guglieri, Nicolas Deconinck, Nicoline Løkken, Omar Abdel‐Mannan, Pia Gallano, Roberto Fernández‐Torrón, Ulrike Schara‐Schmidt, Vincenzo Nigro, Vittoria Zangaro   +72 more
wiley   +1 more source