Results 51 to 60 of about 23,891 (203)

Cromakalim (BRL 34915) restores in vitro the membrane potential of depolarized human skeletal muscle fibres [PDF]

, 1989
The purpose of the present study was to analyze the effects of cromakalim (BRL 34915), a potent drug from a new class of drugs characterized as K+ channel openers, on the electrical activity of human skeletal muscle.
Grafe, Peter, Lehmann-Horn, Frank, Spuler, A.   +2 more
core   +1 more source

Effect of ropivacaine combined with pancuronium on neuromuscular transmission and effectiveness of neostigmine and 4-aminopyridine for blockade reversal: experimental study

Revista Brasileira de Anestesiologia, 2015
BACKGROUND AND OBJECTIVES: The local anesthetic effects on neuromuscular junction and its influence on blockade produced by nondepolarizing neuromuscular blockers are still under-investigated; however, this interaction has been described in experimental ...
Angélica de Fátima Braga, Vanessa Henriques Carvalho, Franklin Sarmento Braga, Gloria Maria Braga Potério, Filipe Nadir Caparica Santos   +4 more
doaj   +3 more sources

A covalently bound photoisomerizable agonist. Comparison with reversibly bound agonists at electrophorus electroplaques [PDF]

, 1980
After disulphide bonds are reduced with dithiothreitol, trans-3-(alpha-bromomethyl)-3’-[alpha-(trimethylammonium)methyl]azobenzene (trans-QBr) alkylates a sulfhydryl group on receptors.
Erlanger, Bernard F., Krouse, Mauri E., Lester, Henry A., Nass, Menasche M., Wassermann, Norbert H.   +4 more
core   +2 more sources

Mechanism-Based Modeling of Neuromuscular Monitoring Measures During General Anesthesia

IEEE Access
This study presents a mechanism-based model of neuromuscular transmission that incorporates the effects of Non-depolarizing Neuromuscular Blockers (NDNBs) used in general anesthesia. NDNBs act on acetylcholine receptors at both the pre- and post-synaptic
Hikaru Hoshino, Hiroki Miyaguchi, Eiko Furutani, Tomonori Sugawara, Toshihiro Takeda, Gotaro Shirakami   +5 more
doaj   +1 more source

Peri-Operative Anaphylaxis—An Investigational Challenge

Frontiers in Immunology, 2019
Patients with suspected peri-operative anaphylaxis (POP) require thorough investigation to identify underlying trigger(s) and enable safe anesthesia for subsequent surgery. The changing epidemiology of POP has been striking.
Siraj A. Misbah, Mamidipudi Thirumala Krishna, Mamidipudi Thirumala Krishna   +2 more
doaj   +1 more source

The relationship between apamin binding and channel block in KCa2 potassium channels. [PDF]

, 2013
Small conductance calcium-activated potassium channels (KCa2.1,2.2,2.3) are widely distributed throughout the body and are involved in diverse physiological processes including the regulation of neuronal firing and smooth muscle contraction.
Benton, DCH, Garbarg, M, Jenkinson, DH, Moss, GWJ   +3 more
core  

Non-compaction cardiomyopathy – brief review [PDF]

, 2017
Left ventricular non-compaction cardiomyopathy is a genetic disorder characterized by the presence of two myocardial layers with numerous prominent trabeculations and deep inter-trabecular recesses that communicate with the ventricular cavity.
Berceanu, Mihaela, Constantin, Anca, Donoiu, Ionuț, Istrătoaie, Octavian, Militaru, Constantin, Mirea, Oana, Mănescu, Mirela, Târtea, Georgică Costinel   +7 more
core   +3 more sources

A clinician’s guide to management of intra-abdominal hypertension and abdominal compartment syndrome in critically ill patients [PDF]

, 2020
This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2020. Other selected articles can be found online at .
A Beurton, A Regli, A Regli, A Reintam Blaser, A Umgelter, A Umgelter, AR Blaser, AW Kirkpatrick, AZ Al-Bahrani, B Keulenaer De, BA Latenser, BL Keulenaer De, CC Petro, CG Ball, EE Frezza, FH Verbrugge, GL Gupte, H Thai, I laet De, I Laet De, I Laet De, IE Laet De, IL Kron, J Bunni, J Oda, JC Duchesne, JJ Waele De, JJ Waele De, JJ Waele De, JJ Waele De, JJL Chionh, KH Kyoung, L Dalfino, L Damme Van, M Tasdogan, MF Struck, MJ Lozada, ML Cheatham, ML Cheatham, ML Cheatham, ML Cheatham, ML Malbrain, ML Malbrain, ML Malbrain, ML Malbrain, ML Malbrain, ML Malbrain, MLNG Malbrain, PRAM Depauw, S Ahmadi-Noorbakhsh   +49 more
core   +1 more source

Long-term use of neuromuscular blockers associated with increased 90-day mortality in mechanically ventilated patients in the ICU: a retrospective cohort study

Zhongguo linchuang yanjiu
Objective To analyze the safety and efficacy of neuromuscular blockers (NMBAs) in mechanically ventilated patients in the ICU. Methods A retrospective analysis was conducted on data from adult patients admitted to the ICU of Deyang People's Hospital ...
LIAO Jian*, LU Dingyu, WU Zhixuan, ZHANG Lian, XIE Hong, WANG Maojuan
doaj   +1 more source

Bloqueio neuromuscular residual após o uso de rocurônio ou cisatracúrio Bloqueo neuromuscular residual después del uso de rocuronio o cisatracúrio Residual neuromuscular block after rocuronium or cisatracurium

Revista Brasileira de Anestesiologia, 2005
JUSTIFICATIVA E OBJETIVOS: O bloqueio neuromuscular residual na sala de recuperação pós-anestésica (SRPA) é um fenômeno que pode aumentar a morbidade pós-operatória, com incidência variando entre 0% e 93%. O objetivo deste estudo foi avaliar a incidência
Bruno Salomé de Morais, Carlos Henrique Viana de Castro, Vera Coelho Teixeira, Alexandre Silva Pinto   +3 more
doaj   +1 more source