Results 91 to 100 of about 112,795 (235)

Mitochondrial dysfunction: Related diseases, influencing factors, and detection

Interdisciplinary Medicine, EarlyView.
Mitochondrial dysfunction is implicated in the pathogenesis of numerous diseases, including neurological disorders, cancers, and cardiovascular conditions, through mechanisms such as mitochondrial DNA mutations, dysregulation of mitochondrial network dynamics, and impaired mitophagy.
Zhaojin Li, Shiyu Li, Wanying Chen, Ziyu Zhang, Chun Pan, Peng Lei, Cheng Cheng, Junyou Zhu, Hanxiao Sun, Zhenning Dai   +9 more
wiley   +1 more source

Suramin inhibits the early effects of PLA(2) neurotoxins at mouse neuromuscular junctions: a twitch tension study [PDF]

, 2011
Several phospholipase A(2) (PLA(2)) neurotoxins from snake venoms can affect acetylcholine release at the neuromuscular junction. In isolated nerve-muscle preparations three distinct phases have been described for this phenomenon: An initial transient ...
Fathi, Behrooz, Harvey, Alan L, Rowan, Edward G   +2 more
core   +1 more source

Ultrasound-guided paravertebral block for pyloromyotomy in 3 neonates with congenital hypertrophic pyloric stenosis [PDF]

, 2015
Background and objectivesHypertrophic pyloric stenosis is a relatively common affection of gastrointestinal tract in childhood that results in symptoms, such as projectile vomiting and metabolic disorders that imply a high risk of aspiration during ...
García-Santigosa, Marta, Guerrero-Domínguez, Rosana, Mata-Gómez, Javier, Ontanilla, Antonio   +3 more
core   +4 more sources

Relaxin‐2 Ameliorates Spinal Cord Injury by Inhibiting Microglia Activation

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aims to assess the therapeutic effectiveness of Relaxin‐2 (RLN‐2) in promoting functional recovery and neuroprotection following spinal cord injury (SCI) in mice. Furthermore, continuous subcutaneous infusion of Serelaxin (0.5 mg/kg/day; human recombinant relaxin‐2) improved neurological recovery, as evidenced by higher Basso ...
Ji‐Huan Wang, Hong‐Biao Sheng, Jun‐Kun Li   +2 more
wiley   +1 more source

Considerations in Neuromuscular Blockade in the ICU: A Case Report and Review of the Literature

Case Reports in Critical Care, 2020
Neuromuscular blocking agents are regularly used in the intensive care unit (ICU) to facilitate mechanical ventilation in patients with acute respiratory distress syndrome and patient-ventilator dyssynchronies.
Jessica D. Workum, Stephanie H.V. Janssen, Hugo R.W. Touw   +2 more
doaj   +1 more source

Light‐Activated Pharmacological Tools for Exploring the Cholinergic System

Medicinal Research Reviews, EarlyView.
ABSTRACT Cholinergic transmission plays a critical role in both the central and peripheral nervous systems, affecting processes such as learning, memory, and inflammation. Conventional cholinergic drugs generally suffer from poor selectivity and temporal precision, leading to undesired effects and limited therapeutic efficacy. Photopharmacology aims to
Alessio Colleoni, Giulia Galli, Clelia Dallanoce, Marco De Amici, Pau Gorostiza, Carlo Matera   +5 more
wiley   +1 more source

Association Between Intermediate-Acting Neuromuscular-Blocking Agents and Short-Term Postoperative Outcomes in Patients with Gastric Cancer

Cancer Management and Research, 2020
Lingxia Niu,1,* Chunlin Yao,1,* Yu Wang,1 Yan Sun,1 Juan Xu,2 Yun Lin,1 Shanglong Yao1 1Department of Anesthesiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei, People’s Republic of ...
Niu L, Yao C, Wang Y, Sun Y, Xu J, Lin Y, Yao S   +6 more
doaj  

Neuromuscular blockade management for intraoperative neural monitoring

Kaohsiung Journal of Medical Sciences, 2020
This article reviews the literature on development of neuromuscular blockade management in thyroid surgery with intraoperative neural monitoring (IONM) in the past decade.
I‐Cheng Lu, Sheng‐Hua Wu, Che‐Wei Wu   +2 more
doaj   +1 more source

Rule Based Expert System for Diagnosis of Neuromuscular Disorders [PDF]

arXiv, 2012
In this paper, we discuss the implementation of a rule based expert system for diagnosing neuromuscular diseases. The proposed system is implemented as a rule based expert system in JESS for the diagnosis of Cerebral Palsy, Multiple Sclerosis, Muscular Dystrophy and Parkinson's disease. In the system, the user is presented with a list of questionnaires
arxiv  

Anesthesia in the surgery of strabismus: role of anesthetic agents in the ocular deviation and surgical outcome [PDF]

, 2015
Purpose: To determine whether the changes in the ocular alignment following general anesthesia, maintained with two different inhalational anesthetic agents, sevoflurane and desflurane, can be used as a predictor for surgical outcomes in children with ...
Arrico, Loredana, Cannata, Riccardo, Collini, Saul, Malagola, Romualdo, Migliorini, Raffaele, Servidio, Annalisa   +5 more
core   +1 more source