Results 141 to 150 of about 112,795 (235)

Effects of HMG CoA reductase (HMGCR) deficiency on skeletal muscle development

The FEBS Journal, EarlyView.
Three skeletal muscle diseases are linked to HMGCR, a key enzyme in cholesterol synthesis. These diseases include a muscular dystrophy associated with pathogenic variants in the HMGCR gene, statin‐associated myopathy, and autoimmune anti‐HMGCR myopathy.
Mekala Gunasekaran, Hannah R. Littel, Natalya M. Wells, Johnnie Turner, Gloriana Campos, Sree Venigalla, Elicia A. Estrella, Partha S. Ghosh, Audrey L. Daugherty, Seth A. Stafki, Louis M. Kunkel, A. Reghan Foley, Sandra Donkervoort, Carsten G. Bönnemann, Laura Toledo‐Bravo de Laguna, Andres Nascimento, Daniel Natera‐de Benito, Isabelle Draper, Christine C. Bruels, Christina A. Pacak, Peter B. Kang   +20 more
wiley   +1 more source

Socially Stable Matchings [PDF]

arXiv, 2013
In two-sided matching markets, the agents are partitioned into two sets. Each agent wishes to be matched to an agent in the other set and has a strict preference over these potential matches. A matching is stable if there are no blocking pairs, i.e., no pair of agents that prefer each other to their assigned matches. In this paper we study a variant of
arxiv  

AUTONOMIC/NEUROMUSCULAR DOSE-RATIOS AND HEMODYNAMIC EFFECTS OF BW785U, A SHORT-ACTING NONDEPOLARIZING ESTER NEUROMUSCULAR BLOCKING AGENT [PDF]

, 1979
William B. Wastila, John J. Savarese
openalex   +1 more source

Activating AMPK improves pathological phenotypes due to mtDNA depletion

The FEBS Journal, Volume 292, Issue 9, Page 2359-2380, May 2025.
In a cellular model of mitochondrial disease characterized by progressive mitochondrial DNA (mtDNA) depletion, we found that advancing mitochondrial dysfunction triggers the early and specific activation of the mitochondria‐associated pool of AMP‐activated protein kinase (AMPK), a master regulator of energy homeostasis.
Gustavo Carvalho, Tran V. H. Nguyen, Bruno Repolês, Josefin M. E. Forslund, W. M. Ruchitha Rukmal Wijethunga, Farahnaz Ranjbarian, Isabela C. Mendes, Choco Michael Gorospe, Namrata Chaudhari, Micol Falabella, Mara Doimo, Sjoerd Wanrooij, Robert D. S. Pitceathly, Anders Hofer, Paulina H. Wanrooij   +14 more
wiley   +1 more source

Aktuelni problemi u primeni mišićnih relaksanata u kliničkoj praksi [PDF]

Vojnosanitetski Pregled, 2003
Konstantinović Slavko, Balkanov Trajan
doaj   +1 more source

Mammalian TatD DNase domain containing 1 (TATDN1) is a proteostasis‐responsive gene with roles in ventricular structure and neuromuscular function

The FEBS Journal, EarlyView.
Twin‐arginine translocation D (TatD) homologs are found across all kingdoms, with debated roles in DNA degradation and protein quality control in unicellular organisms. We characterize TATDN1, the mammalian TatD orthologue, as a proteostatic stress‐responsive cytosolic protein dispensable for DNA degradation.
Gisel Barés, Aida Beà, Anna Sancho‐Balsells, Juan G Valero, David Aluja, Javier Inserte, Sandra García‐Carpi, Elisabet Miró‐Casas, Sara Borràs‐Pernas, Sara Hernández, Ana Martínez‐Val, Jesper V Olsen, Francesc Tebar, Xavier Cañas, Joan X. Comella, Patricia Pérez‐Galán, Marisol Ruiz‐Meana, Albert Giralt, Marta Llovera, Daniel Sanchis   +19 more
wiley   +1 more source

Wireless Silent Speech Interface Using Multi-Channel Textile EMG Sensors Integrated into Headphones [PDF]

arXiv
This paper presents a novel wireless silent speech interface (SSI) integrating multi-channel textile-based EMG electrodes into headphone earmuff for real-time, hands-free communication. Unlike conventional patch-based EMG systems, which require large-area electrodes on the face or neck, our approach ensures comfort, discretion, and wearability while ...
arxiv  

Molecular mechanism for transcriptional regulation of the parathyroid hormone gene by Epiprofin

The FEBS Journal, EarlyView.
The secretion of parathyroid hormone (PTH) from the chief cells in the parathyroid glands is regulated by the concentration of extracellular calcium. Epiprofin (Epfn) expression is induced by NFATc2 in response to elevated serum calcium, and Epfn negatively regulates PTH production.
Takashi Nakamura, Hannah M. Nakamura, Yasumasa Iwasaki, Motomi Enomoto‐Iwamoto, Noriaki Nakashima, Satoshi Fukumoto, Maurizio Pacifici, Masahiro Iwamoto, Minoru Wakamori   +8 more
wiley   +1 more source

Prolonged neuromuscular blockade by non-depolarizing neuromuscular blocking agents

JA Clinical Reports, 2019
Michiko Higashi, Takahiro Tamura, Yushi U. Adachi   +2 more
doaj   +1 more source

The dose response effect of long-acting nondepolarizing neuromuscular blocking agents in children [PDF]

, 1984
Nishan G. Goudsouzian, Jeevendra J. A. Martyn, Letty M. P. Liu, Hassan H. Ali   +3 more
openalex   +1 more source