Results 181 to 190 of about 17,482 (208)
Some of the next articles are maybe not open access.
2010
Neuromuscular blocking agents have, perhaps, the most fascinating history among the drugs used in anesthesiology and intensive care. For centuries, South American aborigines had used curare to hunt animals before Claude Bernard showed in 1850 that these drugs act peripherally, blocking conduction where motor nerves meet the muscle.1 These historical ...
Gerardo Rodríguez +2 more
openaire +1 more source
Neuromuscular blocking agents have, perhaps, the most fascinating history among the drugs used in anesthesiology and intensive care. For centuries, South American aborigines had used curare to hunt animals before Claude Bernard showed in 1850 that these drugs act peripherally, blocking conduction where motor nerves meet the muscle.1 These historical ...
Gerardo Rodríguez +2 more
openaire +1 more source
Reactions Weekly, 2012
The effect of different antiepileptic drugs on the pharmacokinetics of various neuromuscular blocking agents including atracurium, cisatracurium, doxacurium, mivacurium, pancuronium, pipecuronium, rapacuronium, rocuronium and vecuronium are described. Also, potential pharmacodynamic interactions are highlighted.
openaire +2 more sources
The effect of different antiepileptic drugs on the pharmacokinetics of various neuromuscular blocking agents including atracurium, cisatracurium, doxacurium, mivacurium, pancuronium, pipecuronium, rapacuronium, rocuronium and vecuronium are described. Also, potential pharmacodynamic interactions are highlighted.
openaire +2 more sources
2017
Neuromuscular blockade is used in the operating room and in the intensive care unit. While in the operating room, almost every patient undergoing general anesthesia receives neuromuscular blocking agents, in the intensive care unit setting, curarization is reserved only to some patients.
Bignami E., Saglietti F.
openaire +3 more sources
Neuromuscular blockade is used in the operating room and in the intensive care unit. While in the operating room, almost every patient undergoing general anesthesia receives neuromuscular blocking agents, in the intensive care unit setting, curarization is reserved only to some patients.
Bignami E., Saglietti F.
openaire +3 more sources
Journal of Pharmacy Practice, 1994
Neuromuscular blocking (NMB) agents are frequently used in the operating room (OR) as well as the intensive care units. The number of NMB agents available for use in these areas continues to increase. The clinician currently has 10 agents from which to choose, with another (rocuronium) soon to be available.
openaire +1 more source
Neuromuscular blocking (NMB) agents are frequently used in the operating room (OR) as well as the intensive care units. The number of NMB agents available for use in these areas continues to increase. The clinician currently has 10 agents from which to choose, with another (rocuronium) soon to be available.
openaire +1 more source
Isomeric Carborane Neuromuscular Blocking Agents
ChemMedChem, 2019AbstractWe synthesized a family of neuromuscular blocking agents (NMB) based on decamethonium, but containing a carborane cluster in the methylene chain between the two quaternary ammonium groups. The carborane cluster isomers o‐NMB, m‐NMB, and p‐NMB were tested in animals for neuromuscular block and compared with agents used clinically: rocuronium and
Lalit N. Goswami +8 more
openaire +2 more sources
LITHIUM CARBONATE AND NEUROMUSCULAR BLOCKING AGENTS
Survey of Anesthesiology, 1977The effects of lithium carbonate on the responses to five neuromuscular blocking agents were evaluated in dogs anesthetized with halothane (1 per cent) and N2O (60 per cent) in O2. Latency (time from first twitch-height depression to maximal blockade), maximal twitch-height depression, and times to return to 50 per cent and 100 per cent control twitch ...
G E, Hill, K C, Wong, M R, Hodges
openaire +2 more sources
1990
In animal experiments succinylcholine increases ICP (Cottrell et al. 1983, Lanier et al. 1986). The increase in ICP is also observed after pre-treatment with thiopentone (Thiagarajah et al. 1988). In dogs subjected to succinylcholine injection, CBF increases within a few minutes and this hyperperfusion is accompanied by EEG activation (Mori et al. 1973,
Jörn Bo Madsen, Georg Emil Cold
openaire +1 more source
In animal experiments succinylcholine increases ICP (Cottrell et al. 1983, Lanier et al. 1986). The increase in ICP is also observed after pre-treatment with thiopentone (Thiagarajah et al. 1988). In dogs subjected to succinylcholine injection, CBF increases within a few minutes and this hyperperfusion is accompanied by EEG activation (Mori et al. 1973,
Jörn Bo Madsen, Georg Emil Cold
openaire +1 more source
Disadvantages of Neuromuscular Blocking Agents
Veterinary Clinics of North America: Small Animal Practice, 1992Neuromuscular blocking agents have few indications and significant contraindications or problems associated with their use. The need for controlled ventilation and the difficulties of monitoring anesthetic depth when using neuromuscular blocking agents are overriding factors that mitigate against their routine use.
openaire +2 more sources
Neuromuscular Blocking Agents in ARDS
New England Journal of Medicine, 2010In this issue of the Journal, Papazian and colleagues1 present intriguing results of their study examining neuromuscular blockade in patients with severe, early acute respiratory distress syndrome (ARDS). The investigators randomly assigned 340 patients to receive the neuromuscular blocking agent cisatracurium or placebo for a period of 48 hours.
openaire +2 more sources