Results 61 to 70 of about 16,696 (258)

Newer Neuromuscular Blocking Agents [PDF]

Pharmacology & Toxicology, 1994
Four neuromuscular blocking drugs, doxacurium, mivacurium, pipecuronium, and rocuronium have been or are about to be introduced into clinical practice. The purpose of this MiniReview is to describe their pharmacology, to consider their place in clinical anaesthetic practice, and to examine whether the needs of the clinican have been met.
openaire   +3 more sources

Focus on the agents most frequently responsible for perioperative anaphylaxis

Clinical and Molecular Allergy, 2018
Adverse reactions (ARs) to drugs administered during general anesthesia may be very severe and life-threatening, with a mortality rate ranging from 3 to 9%. The adverse reactions to drugs may be IgE and non-IgE-mediated.
E. Di Leo, P. Delle Donne, G. F. Calogiuri, L. Macchia, E. Nettis   +4 more
doaj   +1 more source

Managing Persistent Radial Artery Spasm During Coronary Catheterization: A Complex Case Study

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT This case report details the management of persistent radial artery spasm during coronary catheterization, unresponsive to standard pharmacotherapy. After conventional methods failed, deep sedation, neuromuscular blockade, and orotracheal intubation proved essential.
Riccardo Mager, Carlo Gaspardone, Rosaria Sofia, Cosmo Godino   +3 more
wiley   +1 more source

NSAIDS AS MODULATORS OF CATION CHANNELS: FENAMATES REPURPOSING IN CHANNELOPATHIES

ChemMedChem, Accepted Article.
Cationic ion channels are transmembrane proteins that regulate the flux of cations (potassium, sodium, and calcium) across cell membrane, playing a pivotal role in many cellular functions. Disruptions of their activity can lead to the so‐called genetic or acquired channelopathies, a heterogeneous group of diseases that affect multiple human systems ...
Paola Laghetti, Concetta Altamura, Simone Dell’Atti, Jean-François Desaphy, Ilaria Saltarella   +4 more
wiley   +1 more source

Electromyographic Study of Differential Sensitivity to Succinylcholine of the Diaphragm, Laryngeal and Somatic Muscles: A Swine Model

Kaohsiung Journal of Medical Sciences, 2010
Neuromuscular blocking agents (NMBAs) might diminish the electromyography signal of the vocalis muscles during intraoperative neuromonitoring of the recurrent laryngeal nerve.
I-Cheng Lu, Hsun-Mo Wang, Yi-Wei Kuo, Chia-Fang Shieh, Feng-Yu Chiang, Che-Wei Wu, Cheng-Jing Tsai   +6 more
doaj   +1 more source

The endocannabinoid system regulates both ependymoglial and neuronal cell responses to a tail amputation in the axolotl

Developmental Dynamics, EarlyView.
Abstract Background The endocannabinoid system is a neuromodulatory system implicated in cellular processes during both development and regeneration. The Mexican axolotl, one of only a few vertebrates capable of central nervous system regeneration, was used to examine the role of the endocannabinoid system in the regeneration of the tail and spinal ...
Michael Tolentino, Sarah E. Walker, Gaynor E. Spencer, Robert Carlone   +3 more
wiley   +1 more source

Role of selenium in the pathophysiology of cardiorenal anaemia syndrome

ESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai, Minoru Yasukawa, Shigeru Shibata   +2 more
wiley   +1 more source

Diagnostic value of computed tomography‐based muscle quality and metabolic signatures in heart failure with sarcopenia

ESC Heart Failure, EarlyView.
Abstract Aims Sarcopenia is a major comorbidity in heart failure (HF) patients, but its comprehensive evaluation remains challenging due to resource limitations. Computed tomography (CT) imaging allows opportunistic assessment of both muscle quantity and quality; however, its diagnostic utility and relationships with physical performance and underlying
Wataru Kawaharata, Hidemichi Kouzu, Keishi Ogura, Toshiyuki Yano, Satoshi Katano, Ryo Numazawa, Ryohei Nagaoka, Hiroki Aida, Katsuhiko Ohori, Ryo Nishikawa, Takefumi Fujito, Nobutaka Nagano, Marenao Tanaka, Masato Furuhashi   +13 more
wiley   +1 more source

Genotype‐guided cardiac device intervention in LMNA‐related cardiac conduction disorder: The need for timely genetic testing

European Journal of Heart Failure, EarlyView.
Sudden cardiac death is a catastrophic event, making its prevention important. However, patient selection for primary prevention remains controversial. We report two cases of cardiac conduction disorder initially treated with permanent pacemaker implantation.
Shunsuke Inoue, Zhehao Dai, Tsukasa Oshima, Seitaro Nomura, Takashi Hiruma, Ryo Abe, Kanna Fujita, Manami Katoh, Toshiyuki Ko, Yu Shimizu, Masamichi Ito, Kenichiro Yamagata, Junichi Ishida, Eisuke Amiya, Masaru Hatano, Norifumi Takeda, Hiroyuki Morita, Katsuhito Fujiu, Norihiko Takeda, Issei Komuro   +19 more
wiley   +1 more source

BILE SALTS AND NEUROMUSCULAR BLOCKING AGENTS

British Journal of Anaesthesia, 1981
The influence of the primary bile salts taurocholate and chenodeoxycholate on the neuromuscular blockade of the non-depolarizing drugs Org 6368, pancuronium, Org NC 45 and hexafluorenium was studied in cats. An increase in the effects of these agents, all possessing widely varying molecular structures, was found following administration of the bile ...
D.K.F. Meijer, M. C. Houwertjes, P Westra, H. Wesseling   +3 more
openaire   +4 more sources