Results 121 to 130 of about 3,371 (156)
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DEPOLARIZING NEUROMUSCULAR BLOCKING AGENTS AND INTRAOCULAR PRESSURE IN VIVO
Anesthesiology, 1957J B Dillon, D B Taylor, Dillon John B
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Anesthesiology, 2001
Background Newborn neuromuscular junctions are more sensitive to d-tubocurarine than more mature preparations. It is unclear whether the same modifications occur with newer nondepolarizing agents and depolarizing agent succinylcholine.
F Donati +2 more
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Background Newborn neuromuscular junctions are more sensitive to d-tubocurarine than more mature preparations. It is unclear whether the same modifications occur with newer nondepolarizing agents and depolarizing agent succinylcholine.
F Donati +2 more
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Interactions between ORG9426 and other non-depolarizing neuromuscular blocking agents in ratsin vivo
Journal of Anesthesia, 1992In this study, combined neuromuscular blocking effects of ORG9426 with other non-depolarizing neuromuscular blocking agents were investigated. About 20% steady state neuromuscular block was established by a continuous infusion of one of 6 neuromuscular blocking agents (ORG9426, vecuronium, pancuronium, pipecuronium, d-tubocurarine and metocurine). Then
Kazuhiko Watanabe
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Two new short-acting non-depolarizing neuromuscular blocking agents
Experientia, 1972Le chlorure de 1,1′-octamethylene et le methylsulfate de 5,5′-octamethylenebis ont chez le chat un effet de blocage neuro-musculaire non depolarisant, de courte duree. Les comparaisons faites avec des analogues voisins suggerent que l'activite de ces composes est influencee par le degre d'empechement sterique autour des atomes d'azote quaternaire.
F C, Copp +4 more
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Depolarizing Neuromuscular Blocking Agents
2017Succinylcholine was first introduced into clinical practice in the 1950s, and is currently the only depolarizing neuromuscular blocker in use. It is unique among the drugs used for muscle relaxation in its rapid onset and short duration of action. These characteristics account for its extensive use in scenarios requiring emergency control of the airway.
Caroline S. Gross, Zhiling Xiong
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A study in vitro of new short-acting, non-depolarizing neuromuscular blocking agents
Biochemical Pharmacology, 1969Abstract Presently available short-acting, depolarizing myoneural blocking agents have significant side effects such as increased intraocular tension, cardiac arrhythmias desensitization of the postjunctional membrane, skeletal muscle injury and muscle pains. Non-depolarizing blocking drugs do not produce profound blocks of short duration.
S Ginsburg, R J Kitz
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Identification and Quantitation of Six Non-Depolarizing Neuromuscular Blocking Agents by LC-MS in Biological Fluids [PDF]
Journal of Analytical Toxicology, 2004 A liquid chromatography-electrospray-mass spectrometry technique for the screening and determination of five non-depolarizing neuromuscular blocking agents (NDBAs), atracurium and its product of degradation/metabolite laudanosine, rocuronium, pancuronium, vecuronium, and mivacurium has been developed using ambenonium as the internal standard (I.S ...
Pierre Marquet +2 more
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THE MECHANISMS UNDERLYING NEUROMUSCULAR BLOCK FOLLOWING PROLONGED EXPOSURE TO DEPOLARIZING AGENTS
Annals of the New York Academy of Sciences, 1966A J, Gissen, W L, Nastuk
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Clinical pharmacology of ORG 7617, a short-acting non-depolarizing neuromuscular blocking agent
European Journal of Clinical Pharmacology, 1994The dose-response relationship and the time course of action of Org 7617, a short acting non-depolarizing neuromuscular blocking agent, were evaluated during thiopentone, fentanyl, halothane and N2O anaesthesia. Neuromuscular transmission was monitored mechanomyographically. The ED50 and ED90 were calculated after single bolus doses of the drug. Twelve,
van den Broek, L +4 more
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Acta Anaesthesiologica Scandinavica, 1984
The effect of lignocaine on the depolarization and contracture responses produced by acetylcholine (ACh) or tetraethylammonium (TEA) was studied in the isolated chick biventer cervicis (BVC) nerve‐muscle preparation using the moving fluid electrode technique.
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The effect of lignocaine on the depolarization and contracture responses produced by acetylcholine (ACh) or tetraethylammonium (TEA) was studied in the isolated chick biventer cervicis (BVC) nerve‐muscle preparation using the moving fluid electrode technique.
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