Results 131 to 140 of about 3,371 (156)
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Acta Anaesthesiologica Scandinavica, 1980
We describe the clinical use, for intubation purposes, of Org‐NC45, a new non‐depolarizing neuromuscular blocking agent. Administration of 50 and 72 μg/kg of this drug allowed good to excellent endotracheal intubation conditions within 3 and 2 min, respectively. In none of the cases was a signifcant change in blood pressure or heart rate seen after the
N, Krieg +3 more
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We describe the clinical use, for intubation purposes, of Org‐NC45, a new non‐depolarizing neuromuscular blocking agent. Administration of 50 and 72 μg/kg of this drug allowed good to excellent endotracheal intubation conditions within 3 and 2 min, respectively. In none of the cases was a signifcant change in blood pressure or heart rate seen after the
N, Krieg +3 more
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Colombian Journal of Anesthesiology, 2012 Abstract Objectives To describe the prevalence of use of non-depolarizing neuromuscular blockers/relaxants by anesthesiologists in our area, and the perception of anesthesiologists in the Valle del Cauca region with regards to monitoring. Methodology A descriptive, cross-sectional study including 258 anesthesiologists, and a review of the data ...
Lema Flórez, Eduardo +2 more
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Combining non-depolarizing neuromuscular blocking agents: synergism, addition or antagonism?
Current Opinion in Anaesthesiology, 1999As the quality of currently available relaxants has improved, the need to combine relaxants to minimize the incidence and severity of their side-effects has decreased. Little work has been done in the past year characterizing the effects of combining different non-depolarizing neuromuscular blocking agents.
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Interactions of Volatile Anesthetics with Non-Depolarizing Neuromuscular Blocking Agents
1995Drug interactions involving neuromuscular blocking agents are divided into two classes: one is interaction between neuromuscular blocking drugs and other classes of drug.The second is interactions with neuromuscular blocking agents each other.
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General Pharmacology: The Vascular System, 1999
Pancuronium, vecuronium, and rocuronium produce different cardiac effects. Using spontaneously beating right and electrically stimulated left rat atria, while measuring developed force, effective refractory period, and heart rate, we determined and compared the concentration-dependent cardiac effects of the compounds.
A L, Melnikov +3 more
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Pancuronium, vecuronium, and rocuronium produce different cardiac effects. Using spontaneously beating right and electrically stimulated left rat atria, while measuring developed force, effective refractory period, and heart rate, we determined and compared the concentration-dependent cardiac effects of the compounds.
A L, Melnikov +3 more
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An analytical pharmacodynamic model for nondepolarizing neuromuscular blocking agents
Journal of Pharmacokinetics and Biopharmaceutics, 1981A pharmacodynamic model for nondepolarizing neuromuscular blocking agents (NMBA) is developed and tested with different sets of data (NMBA plasma concentration and time evolution of muscular paralysis). This model takes into account the binding of NMBA to the cholinergic motor endplate receptors and thus permits estimation of the apparent equilibrium ...
D'Hollander, Alain, Delcroix, Claude
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Arzneimittel-Forschung, 1982
The pharmacokinetics of 2 beta, 16 beta-bis-(4'-dimethyl-1'-piperazino)-3 alpha, 17 beta-diacetoxy-5 alpha-androstane dibromide (pipecurium bromide, Arduan), a new non-depolarizing neuromuscular blocking agent, was studied in surgical patients. Plasma concentration-time curves of pipecurium bromide were evaluated by fitting the data to a bi-exponential
E, Tassonyi, G, Szabó, L, Vereczkey
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The pharmacokinetics of 2 beta, 16 beta-bis-(4'-dimethyl-1'-piperazino)-3 alpha, 17 beta-diacetoxy-5 alpha-androstane dibromide (pipecurium bromide, Arduan), a new non-depolarizing neuromuscular blocking agent, was studied in surgical patients. Plasma concentration-time curves of pipecurium bromide were evaluated by fitting the data to a bi-exponential
E, Tassonyi, G, Szabó, L, Vereczkey
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Acta anaesthesiologica Sinica, 1998
Rocuronium is a new nondepolarizing muscle relaxant. It features a rapid onset and lack of histamine release: It has an intermediate onset of action as vecuronium. The purpose of this study was to compare the neuromuscular action and condition of intubation after a bolus dose of rocuronium or vecuronium (2 x ED90).
P L, Lin +5 more
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Rocuronium is a new nondepolarizing muscle relaxant. It features a rapid onset and lack of histamine release: It has an intermediate onset of action as vecuronium. The purpose of this study was to compare the neuromuscular action and condition of intubation after a bolus dose of rocuronium or vecuronium (2 x ED90).
P L, Lin +5 more
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Arzneimittel-Forschung, 1981
A method for the determination of 2 beta, 16 beta-bis (4'dimethyl-1'-piperazino)-3a, 17 beta-diacetoxy-5 alpha-androstane is described. After deproteinization a pipecurium bromide Rose Bengal complex is formed and extracted with chloroform from a mildly basic medium.
G, Szabó, E, Tassonyi
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A method for the determination of 2 beta, 16 beta-bis (4'dimethyl-1'-piperazino)-3a, 17 beta-diacetoxy-5 alpha-androstane is described. After deproteinization a pipecurium bromide Rose Bengal complex is formed and extracted with chloroform from a mildly basic medium.
G, Szabó, E, Tassonyi
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