The effect of non-depolarizing neuromuscular blocking agents on the release of acetylcholine from the right atrium of the guinea pig. [PDF]
Acta medica Okayama, 1997 The effect of various non-depolarizing neuromuscular blocking agents (gallamine, pancuronium, vecuronium, d-tubocurarine, metocurine, atracurium and pipecuronium) on [3H]acetylcholine release in the response to field electrical stimulation was investigated in vitro in preparations of the guinea pig right atrium.
Manabe, Nobuki
openaire +4 more sources
Sugammadex administration in patients with end-stage renal disease: a narrative review with recommendations [PDF]
Anesthesia and Pain Medicine, 2023 Due to unknown safety concerns, sugammadex should not be administered to patients with end-stage renal disease (ESRD). However, because the supply of benzylisoquinolinium-type neuromuscular blocking agents (NMBAs) has been discontinued, rocuronium is the
Seok Kyeong Oh, Byung Gun Lim
doaj +1 more source
Sugammadex: clinical development and practical use [PDF]
Korean Journal of Anesthesiology, 2013 Sugammadex is belonging to a new class of drugs: the selective relaxant binding agents. Sugammadex can reverse residual paralysis by encapsulating free circulating non depolarizing muscle relaxants.
Thomas Fuchs-Buder +2 more
doaj +1 more source
Current clinical application of dantrolene sodium [PDF]
Anesthesia and Pain Medicine, 2023 Dantrolene sodium (DS) was first introduced as an oral antispasmodic drug. However, in 1975, DS was demonstrated to be effective for managing malignant hyperthermia (MH) and was adopted as the primary therapeutic drug after intravenous administration ...
Hong Seuk Yang +5 more
doaj +1 more source
Comparison of the neuromuscular effects of two infusion rates of rocuronium in anesthetized pigs
Acta Veterinaria Scandinavica, 2022 Background: Neuromuscular blocking agents are frequently administered to pigs used for research. In humans, administration of the drugs is not without risk and may result in accidental awareness under general anaesthesia and postoperative residual ...
Kamilla Pedersen +3 more
doaj +1 more source
Neuromuscular blockade management for intraoperative neural monitoring
Kaohsiung Journal of Medical Sciences, 2020 This article reviews the literature on development of neuromuscular blockade management in thyroid surgery with intraoperative neural monitoring (IONM) in the past decade.
I‐Cheng Lu +2 more
doaj +1 more source
Comparative Effectiveness of Calabadion and Sugammadex to Reverse Non-depolarizing Neuromuscular-blocking Agents [PDF]
Anesthesiology, 2015 AbstractAbstract Calabadion 2 rapidly reversed deep rocuronium-, vecuronium-, and cisatracurium-induced neuromuscular blockade in a dose-dependent manner. Calabadion 2 reversed rocuronium- and vecuronium-induced neuromuscularblockade with a 1:1 binding ratio, like sugammadex, but it had a higher in vitro binding affinity and a higher ...
Haerter, Friederike +11 more
openaire +2 more sources
Rocuronium-Sugammadex in Anesthesia for Electroconvulsive Therapy [PDF]
Psikiyatride Güncel Yaklaşımlar, 2016 Electroconvulsive therapy (ECT) is a form of treatment which is very effective in many psychiatric disorders. The administration of anesthesia plays a positive role in the success of ECT and improves the oxygenation of the body during the process ...
Nilay Tas, Esra Yancar Demir
doaj +1 more source
Pharmacodynamic interactions between muscle relaxants and other medications in practice of anesthesia [PDF]
Farmacja Polska, 2023 Knowledge of drug interactions is an essential element of medical practice. Along with the increasing occurrence of multimorbidity and the associated multi-drug use, the number of possible combinations of preparations is constantly rising.
Paweł Radkowski, Rafał Marek Okoński
doaj +1 more source
Neuromuscular blockers and their reversal: have we finally found the on-off switches?
Ain Shams Journal of Anesthesiology, 2021 Background A nondepolarizing neuromuscular blocking agent (NMBA) with a succinylcholine-like quick onset and offset has been the holy grail of the science of neuromuscular blockade.
Shagun Bhatia Shah +3 more
doaj +1 more source