Results 31 to 40 of about 1,601,842 (182)
(1) Background: Pancuronium bromide is a neuromuscular blocker used for immobilizing crocodiles that can be reversed with neostigmine. A recommended drug dose has only been established for saltwater crocodiles (Crocodylus porosus), mostly based on trials
Lionel Schilliger +6 more
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Sugammadex, a selective antagonist of steroidal non‐depolarizing neuromuscular blocking agents, has been used in children in limited circumstances. However, neither pharmacokinetics (PKs) nor recovery profile of sugammadex for intense neuromuscular ...
Sang‐Hwan Ji +8 more
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Sugammadex, a modified gamma-cyclodextrin, has changed clinical practice of neuromuscular reversal dramatically. With the introduction of this selective relaxant binding agent, rapid and reliable neuromuscular reversal from any depth of block became ...
Hajime Iwasaki +3 more
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INFLUENCE OF “PRIMING” ON THE POTENCY OF NON-DEPOLARIZING NEUROMUSCULAR BLOCKING AGENTS
Dose-response curves have been constructed to determine the ED50 and ED95 (doses required to produce a 50% and a 95% block, respectively) following administration of a small "priming" dose of atracurium 50 micrograms kg-1, vecuronium 10 micrograms kg-1 or pancuronium 10 micrograms kg-1.
M M, Brady, R K, Mirakhur, F M, Gibson
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Are non-depolarizing neuromuscular blocking agents innocuous for the neonates? [PDF]
tions and for the initial injection when a continuous infusion is used (for continuous plexus nerve block analgesia). Unfortunately, the labelled syringe used for continuous infusion is not a dedicated one (30 mL is too small: too frequent changes are needed). We use dedicated coiled lines as well (Figure, Vygon laboratories, Ecouen, France).
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Function and distribution of three types of rectifying channel in rat spinal root myelinated axons [PDF]
1. The nature, distribution and function of rectifying channels in rat spinal root myelinated axons has been assessed with selective blocking agents and a variety of intracellular and extracellular recording techniques. 2.
Baker, M. +3 more
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Background: Sugammadex is known to reverse neuromuscular blockade induced by non-depolarizing agents. In children, the recommended dose for reversal of moderate neuromuscular blockade is 2 mg/kg.
Sang-Hwan Ji +17 more
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Studies on fazadinium bromide (AH 8165): A new non-depolarizing neuromuscular blocking agent [PDF]
Intravenous dose-response relationships were used to correlate neuromuscular paralysis with the effects of fazadinium (AH 8165) on autonomic mechanisms in anaesthetized cats and rhesus monkeys and with cardiovascular effects in man. In cats and monkeys neuromuscular paralysis of the twitch responses of the gastrocnemius muscle by fazadinium was ...
R, Hughes, J P, Payne, N, Sugai
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THE NATURE OF ACETYLCHOLINE RECEPTOR [PDF]
The present work with consideratlon to the autoradiographic pictures, suggests that cholinergic receptors are located at the gate of a channel originating from synaptic cleft coming to lie within the muscle fibre. AChE molecules stand at the gate of this
M.E. TASHAYOD
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Malignant hyperthermia – state of knowledge
Malignant hyperthermia (MH) is a relatively rare, but potentially lethal genetic disorder. That disease is characterized by hypermetabolic response of the skeletal muscles caused by exposure to triggering agents e.g. volatile anesthetics or depolarizing
Michał Perszke +6 more
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