Results 201 to 210 of about 8,587 (262)

Exercise during 14 days of head down tilt bedrest attenuates motor unit impairments in older humans

Experimental Physiology, EarlyView.
Abstract Head‐down tilt bedrest (HDBR) models the effects of mechanical unloading on neuromuscular function. The efficacy of exercise in preserving motor unit (MU) function in older adults during HDBR remains unclear. This study investigated the effects of 14‐day HDBR on MU properties in older adults and the protective role of exercise.
Philippe St‐Martin, Jean‐Christophe Lagacé, Mathil Ruel, Ahmed Ghachem, Guillaume Léonard, Eleonor Riesco, Mathew Piasecki, Jamie S. McPhee, Isabelle J. Dionne   +8 more
wiley   +1 more source

Neuroprotective roles of klotho: Molecular pathways and therapeutic implications for cognitive health in neurological and psychiatric diseases

Experimental Physiology, EarlyView.
Abstract Klotho, a pleiotropic protein initially identified for its role in kidney function, has garnered significant attention for its neuroprotective properties in various neurodegenerative diseases. It regulates key processes, such as oxidative stress, neuroinflammation, synaptic plasticity and myelination, all crucial for maintaining neuronal ...
Amir Arsalan Ghahari, Leylinaz Safaeihavadaragh, Mehrdad Nourizadeh, Shaghayegh Davari, Saba Safaei, Farshad Zare, Safa Alkayyat, Erfan Kamali Far   +7 more
wiley   +1 more source

Hyper‐buoyancy flotation increases cervical disc height and reduces vertebral stiffness, with only partial reversal after acute 1 g axial loading

Experimental Physiology, EarlyView.
Abstract Exposure to microgravity is associated with stature increases, moderate‐to‐severe back/neck pain and elevated lumbar and cervical intervertebral disc (IVD) herniation risk post‐flight. Whilst lumbar pathophysiology has been investigated, little attention has been placed on the cervical spine.
D. Marcos‐Lorenzo, P. Hernández Bernal, R. Fernández Corujo, A. Gil Martínez, J. Swanenburg, D. A. Green   +5 more
wiley   +1 more source

A comparison of the neuromuscular, cardiopulmonary and muscle oxygenation responses to single‐ and double‐leg cycling in older adults

Experimental Physiology, EarlyView.
Abstract Previous work in younger adults has shown that during small muscle mass exercise, the tolerable degree of neuromuscular impairment at task failure is greater than during large muscle mass exercise. However, no study has compared the neuromuscular responses to small and large muscle mass exercise whilst matching exercise modality in older ...
Emily Dodd, Callum G. Brownstein
wiley   +1 more source

(Poly)phenols: Mechanisms of action and efficacy of contemporary supplements for exercise recovery and performance

Experimental Physiology, EarlyView.
Abstract (Poly)phenols are a diverse group of bioactive chemical compounds present in a wide range of plant‐ and animal‐based foods. Several thousands of (poly)phenols exist; many have potent biological effects, most notably antioxidant, anti‐inflammatory and vasodilatory.
Glyn Howatson, Tom Clifford
wiley   +1 more source

Reviewer #3 (Public Review): Depletion of SMN protein in mesenchymal progenitors impairs the development of bone and neuromuscular junction in spinal muscular atrophy

openalex   +1 more source

From Earth to orbit: How to preserve muscle health in space and bed rest

Experimental Physiology, EarlyView.
Antonios Matsakas, Colleen Deane
wiley   +1 more source

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Autonomic neuromuscular junctions

Autonomic Neuroscience, 2021
This review traces the history of the discovery and subsequent understanding of smooth muscle cells and their motor innervation. Smooth muscle tissue is made up of thousands of very small, individual, electrically connected, muscle cells. Each axon that enters a smooth muscle tissue branches extensively to form a terminal arbour that comes close to ...
Madeleine R, Di Natale, Martin J, Stebbing, John B, Furness   +2 more
openaire   +2 more sources

Cholinesterases of neuromuscular junction

Neurochemistry International, 1980
The ultrastructural localization of AChE and BuChE was studied in motor endplates of the rat and mouse diaphragms, using the CNS(?) modification of the one-step Cu-thiocholine procedure. AChE activity was observed on pre- and postsynaptic membranes, in the basal lamina and in the Schwann cell-nerve terminal interspace.
M, Brzin, J, Sketelj, Z, Grubi, T, Kiauta   +3 more
openaire   +2 more sources

Neuromuscular Junction Disorders

PM&R, 2013
AbstractDisorders of the neuromuscular junction, such as myasthenia gravis and Lambert‐Eaton myasthenic syndrome, constitute an important and treatable class of diseases. Both disorders are typically caused by an immunologically mediated attack on discrete components of the neuromuscular junction, compromise the efficacy of neurotransmitter ...
Chiawen Lucy, Liang, Steve, Han
openaire   +2 more sources