Depolarization-activated potentiation of the T fiber synapse in the blue crab [PDF]
The blue crab T fiber synapse, associated with the stretch receptor of the swimming leg, has a nonspiking presynaptic element that mediates tonic transmission.
Lin, J.-W., Llinas, R.
core
Altered Function of the DnaJ Family Cochaperone DNJ-17 Modulates Locomotor Circuit Activity in a Caenorhabditis elegans Seizure Model. [PDF]
The highly conserved cochaperone DnaJ/Hsp40 family proteins are known to interact with molecular chaperone Hsp70, and can regulate many cellular processes including protein folding, translocation, and degradation.
Jin, Yishi, Takayanagi-Kiya, Seika
core +2 more sources
Electrophysiological study in neuromuscular junction disorders
This review is on ultrastructure and subcellular physiology at normal and abnormal neuromuscular junctions. The clinical and electrophysiological findings in myasthenia gravis, Lambert-Eaton myasthenic syndrome (LEMS), congenital myasthenic syndromes ...
Ajith Cherian +2 more
doaj +1 more source
Objectives Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies. To help patients and providers in the decision‐making process, we developed
Anahita Deboo +19 more
wiley +1 more source
Motoneuron Wnts regulate neuromuscular junction development
The neuromuscular junction (NMJ) is a synapse between motoneurons and skeletal muscles to control motor behavior. Unlike extensively investigated postsynaptic differentiation, less is known about mechanisms of presynaptic assembly.
Chengyong Shen +14 more
doaj +1 more source
Liquid Crystal Elastomers Under Confinement: A Review of Template‐Based Fabrication and Applications
Template‐assisted confinement offers powerful ways to control the alignment, structure, and function of liquid crystal elastomers. This review highlights several templating strategies and details how geometry and interfaces shape material responses.
Meng Zhang +7 more
wiley +1 more source
Mathematical modeling of the Drosophila neuromuscular junction [PDF]
Poster presentation: An important challenge in neuroscience is understanding how networks of neurons go about processing information. Synapses are thought to play an essential role in cellular information processing however quantitative and mathematical ...
Bucher, Daniel +4 more
core +1 more source
Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim +4 more
wiley +1 more source
SnapShot: Neuromuscular Junction
Agrin MuSK Dok-7Rapsyn AChR AChE ChAT Nav1.4Auto-antibodiesto AChRsAuto-antibodiesto MuSKHypomorphic mutations in thesegenes impair postsynaptic differentiation. The number of AChRs at synapses is reduced, which compromises the reliability of synaptic transmission and leads to muscle weakness and fatigue.
openaire +2 more sources
Sexually Dimorphic Neurotransmitter Release at the Neuromuscular Junction in Adult Caenorhabditis elegans [PDF]
Zhenzhen Yan +5 more
openalex +1 more source

