Results 71 to 80 of about 77,782 (191)

Mitochondrial dysfunction: Related diseases, influencing factors, and detection

Interdisciplinary Medicine, EarlyView.
Mitochondrial dysfunction is implicated in the pathogenesis of numerous diseases, including neurological disorders, cancers, and cardiovascular conditions, through mechanisms such as mitochondrial DNA mutations, dysregulation of mitochondrial network dynamics, and impaired mitophagy.
Zhaojin Li, Shiyu Li, Wanying Chen, Ziyu Zhang, Chun Pan, Peng Lei, Cheng Cheng, Junyou Zhu, Hanxiao Sun, Zhenning Dai   +9 more
wiley   +1 more source

Neuro-Protection and Neuro-Therapy Effects of Acalypha Indica Linn. Water Extract Ex Vivo on Musculus Gastrocnemius Frog [PDF]

, 2008
The studies of neuro-protection and neuro-therapy effects of Acalypha indica Linn. water extract ex vivo on Musculus gastrocnemius frog have already done at three Departments in Faculty of Medicine, University of Indonesia.
Ibrahim, N. (Nurhadi), Purwaningsih, E. H. (Ernie), Tedjo, A. (Arjo), Zain, H. (Hamdani)   +3 more
core   +1 more source

Prenatal Diagnosis and Prognostic Factors in Fetuses With Arthrogryposis Multiplex Congenita—A Systematic Review

Journal of Clinical Ultrasound, EarlyView.
Arthrogryposis Multiplex Congenita (AMC) is characterized by the presence of multiple joint contractures in the fetus' body. The diagnosis of arthrogryposis is complex and often missed prenatally. This comprehensive review of the literature published over the last 20 years, with an emphasis on the role of prenatal ultrasound in predicting postnatal ...
Mario Brock Leao, Marianna Facchinetti Brock, Jorge Roberto Di Tommaso Leao, Gianpaolo Grisolia, Mario Lituania, Samantha Erin Neumann, Gabriele Tonni, Rodrigo Ruano   +7 more
wiley   +1 more source

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

Genetically‐targeted control of the spinal cord and peripheral nervous system

Journal of Intelligent Medicine, EarlyView.
Application of genetically‐targeted stimulation for treating diseases or injuries outside the brain. Optogenetic and chemogenetic systems have been developed for dysfunction in the cochlea, spinal cord, dorsal root ganglia (DRGs), peripheral nerves, lower urinary tract, and enteric nervous system (ENS). Created with Biorender.com.
Anakaren Romero Lozano, Victoria Koptelova, Zoya Ahmad, Huiliang (Evan) Wang   +3 more
wiley   +1 more source

Reference Values for Water‐Specific T1, Intermuscular and Intramuscular Fat Content in Skeletal Muscle at 2.89 T

Journal of Magnetic Resonance Imaging, EarlyView.
Background MRI offers quantification of proton density fat fraction (PDFF) and tissue characteristics with T1 mapping. The influence of age, sex, and the potential confounding effects of fat on T1 values in skeletal muscle in healthy adults are insufficiently known.
Stephen J. Foulkes, Mark J. Haykowsky, Rachel Sherrington, Amy A. Kirkham, Justin Grenier, Peter Seres, David I. Paterson, Richard B. Thompson   +7 more
wiley   +1 more source

Relaxin‐2 Ameliorates Spinal Cord Injury by Inhibiting Microglia Activation

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aims to assess the therapeutic effectiveness of Relaxin‐2 (RLN‐2) in promoting functional recovery and neuroprotection following spinal cord injury (SCI) in mice. Furthermore, continuous subcutaneous infusion of Serelaxin (0.5 mg/kg/day; human recombinant relaxin‐2) improved neurological recovery, as evidenced by higher Basso ...
Ji‐Huan Wang, Hong‐Biao Sheng, Jun‐Kun Li   +2 more
wiley   +1 more source

Laryngeal Reinnervation vs Type I Thyroplasty in Unilateral Vocal Fold Paralysis (VOCALIST): A Randomized Feasibility Study

The Laryngoscope, EarlyView.
VOCALIST feasibility study demonstrated that conducting a multi‐centre phase III randomized controlled trial comparing laryngeal reinnervation and type I thyroplasty for unilateral vocal fold paralysis (UVFP) in UK is achievable. Recruitment, randomization, and data collection were successful, and outcome measures for voice, swallowing, and quality of ...
Martin Birchall, Eleftheria Iliadou, Helen Blackshaw, Marcus Jepson, Paul Carding, Samantha Husbands, Kate Heathcote, Marina Mat Baki, Yakubu Karagama, Gareth Ambler   +9 more
wiley   +1 more source

Recent Advances in Stimuli‐Responsive Conductive Hydrogels for Smart Sensing and Actuation: Properties, Design Strategies, and Applications

Macromolecular Materials and Engineering, EarlyView.
Abstract Conductive hydrogels are a class of multifunctional composites constructed by introducing conductive components into a three‐dimensional polymer network, combining the high water‐content, stretchability, and biocompatibility of traditional hydrogels.
Lulu Li, Xidi Sun, Yuchen Guo, Wen Cheng, Yi Shi, Lijia Pan   +5 more
wiley   +1 more source

A comparative study of different induction techniques (Propofol-Placebo, Propofol-Ephedrine and Propofol- Placebo-Crystalloid) on intubating conditions after rocuronium administration [PDF]

, 2007
This was a prospective randomized double blind controlled study to compare intubating conditions at 60 seconds with rocuronium 0.6 mg/kg by using three different induction techniques: propofol-placebo (PP), propofol-ephedrine (PE) and propofol ...
Karis Misiran,, Muhd Helmi Azmi,
core