Results 91 to 100 of about 59,488 (252)

Status and future of recombinant adeno‐associated virus vector manufacturing

Biotechnology Progress, EarlyView.
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley   +1 more source

Effect of Intraoperative Low-Dose Lidocaine Administration on the Consumption of Mivacurium During Gynecological Laparoscopic Surgery: A Prospective Clinical Study

Drug Design, Development and Therapy
Jin-Peng Fu,1,2 Yan-Hong Zhou,2 Shu-Xi Li,2 Ying-Jie Yang,2 Qian Wang,2,3 Wan Lei,2,4 Jian-Jun Shen,5 Yuan-Liang Chen,1 Li-Li Xu2 1Department of Anesthesia, Jinhua Municipal Central Hospital, Jinhua, Zhejiang, People’s Republic of China; 2Department of ...
Fu JP, Zhou YH, Li SX, Yang YJ, Wang Q, Lei W, Shen JJ, Chen YL, Xu LL   +8 more
doaj  

Neuromuscular Monitoring and Wake-Up Test During Scoliosis Surgery. [PDF]

Cureus, 2023
Paunikar S, Paul A, Wanjari D, Alaspurkar NR.   +3 more
europepmc   +1 more source

Development of a Zebrafish Embryo‐Based Test System for Thyroid Hormone System Disruption: 3Rs in Ecotoxicological Research

Environmental Toxicology and Chemistry, EarlyView.
Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz, Melanie Blanc‐Legendre, Maximilian Rinderknecht, Laura Behnstedt, Sara Coordes, Luisa Reger, Sacha Sire, Xavier Cousin, Thomas Braunbeck, Lisa Baumann   +9 more
wiley   +1 more source

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

Equine Veterinary Journal, EarlyView.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska, Jowita Grzędzicka‐Agko, Paula Kiełbik, Michał Trela, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Similar locomotor patterns across Quarter Horse disciplines inform lameness assessment

Equine Veterinary Journal, EarlyView.
Abstract Background Lineage‐based selection is central to the Quarter Horse industry and is often justified by the assumption that morphology determines locomotor function. However, objective evidence linking static conformation to discipline‐specific locomotor behaviour under standardised conditions remains limited.
Renata Farinelli de Siqueira, Lavínia Andressa Brito, Isabela Marques de Figueiredo, Ana Clara Rocha dos Santos, Larissa Santos dos Anjos   +4 more
wiley   +1 more source

Neuromuscular blockade in cardiac surgery: An update for clinicians

Annals of Cardiac Anaesthesia, 2008
There have been great advancements in cardiac surgery over the last two decades; the widespread use of off-pump aortocoronary bypass surgery, minimally invasive cardiac surgery, and robotic surgery have also changed the face of cardiac anaesthesia.
Hemmerling Thomas, Russo Gianluca, Bracco David   +2 more
doaj  

Effects of flow‐controlled expiration on oxygenation and early recovery in horses undergoing general anaesthesia

Equine Veterinary Journal, EarlyView.
Abstract Background FLow‐controlled EXpiration (FLEX) has been shown to significantly enhance oxygenation in horses under clinical and experimental conditions. Objectives To compare pulmonary gas exchange during early recovery following general anaesthesia in horses ventilated with FLEX compared with conventional intermittent positive pressure ...
Allison Mika, Jerrianne Brandly, Alycia Frampton, Hope Douglas, Miranda Starr, Henry Benchimol, Klaus Hopster   +6 more
wiley   +1 more source

Reversal of Rocuronium Induced Muscle Relaxation with Sugammadex versus Neostigmine in Patients Undergoing General Anaesthesia: A Randomised Controlled Trial

Journal of Clinical and Diagnostic Research
Introduction: Prolonged effects of neuromuscular blocking medications can lead to complications after surgery or the risk of Postoperative Residual Curarisation (PORC) in the postanaesthesia care unit, which may increase morbidity in surgical patients ...
Ankur Garg, Kirti Gupta, Richa Chandra, Jyoti Pathania, Malti Agrawal   +4 more
doaj   +1 more source

Monitoring Neuromuscular Blockade

International Anesthesiology Clinics, 2004
Glenn S, Murphy, Joseph W, Szokol
openaire   +2 more sources