Results 61 to 70 of about 115,229 (304)

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein   +13 more
wiley   +1 more source

Improving translational studies: lessons from rare neuromuscular diseases [PDF]

open access: yes, 2015
Animal models play a key role in the development of novel treatments for human disease. This is particularly true for rare diseases – defined as disorders that affect less than 1 in 2000 people in the human population – for which, very often, there are ...
Wells, D J
core   +3 more sources

Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas   +39 more
wiley   +1 more source

Mechanism-Based Modeling of Neuromuscular Monitoring Measures During General Anesthesia

open access: yesIEEE Access
This study presents a mechanism-based model of neuromuscular transmission that incorporates the effects of Non-depolarizing Neuromuscular Blockers (NDNBs) used in general anesthesia. NDNBs act on acetylcholine receptors at both the pre- and post-synaptic
Hikaru Hoshino   +5 more
doaj   +1 more source

Effect of plyometric training on swimming block start performance in adolescents [PDF]

open access: yes, 2009
This study aimed to identify the effect of plyometric training (PT), when added to habitual training (HT) regimes, on swim start performance. After the completion of a baseline competitive swim start, 22 adolescent swimmers were randomly assigned to ...
  +10 more
core   +1 more source

Muscle fiber typology substantially influences time to recover from high-intensity exercise [PDF]

open access: yes, 2020
Human fast-twitch muscle fi- bers generate high power in a short amount of time but are easily fatigued, whereas slow-twitch fibers are more fatigue resistant.
Bex, Tine   +3 more
core   +2 more sources

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu   +10 more
wiley   +1 more source

Dose–Response Evaluation of Sugammadex for Reversal of Deep Rocuronium-Induced Neuromuscular Block in Cats

open access: yesVeterinary Sciences
Background: Sugammadex is a selective γ-cyclodextrin compound that encapsulates steroidal neuromuscular blocking agents such as rocuronium, allowing rapid and predictable recovery from neuromuscular block (NMB).
Natália Mesquita Cesnik   +6 more
doaj   +1 more source

Comparison of velocity-based and traditional 1RM-percent-based prescription on acute kinetic and kinematic variables [PDF]

open access: yes, 2018
Purpose: This study compared kinetic and kinematic data from three different velocity-based training (VBT) sessions and a 1-repetition maximum (1RM) percent-based training (PBT) session using full-depth, free-weight back squats with maximal concentric
Banyard, Harry G.   +4 more
core   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane   +43 more
wiley   +1 more source

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