Results 61 to 70 of about 3,896,599 (361)

Relationship between first-twitch depression and train-of-four ratio during sugammadex reversal of rocuronium-induced neuromuscular blockade [PDF]

Korean Journal of Anesthesiology, 2016
BackgroundThe primary outcome of sugammadex reversal for rocuronium-induced neuromuscular block (NMB) is a train-of-four ratio (TOFR) of 0.9, not first twitch (T1) height.
Kyo Sang Kim, You Na Oh, Tae Yeon Kim, Song Yee Oh, Yeong Hun Sin   +4 more
doaj   +1 more source

Diaphragm ultrasonography as a monitor in assessing antagonistic effect of sugammadex on rocuronium in patients with Child-Pugh grades A and B

Frontiers in Medicine
BackgroundAlthough diaphragm ultrasound can be used for detecting residual neuromuscular blockade post-surgery, there exists notable dearth in contemporary research exploring the correlation between preoperative Child-Pugh classification and the ...
Yan Sun, Yan Sun, Yan Sun, Shujun Sun, Shujun Sun, Shujun Sun, Rui Chen, Rui Chen, Rui Chen, Jiwei Shen, Jiwei Shen, Jiwei Shen, Xiangdong Chen, Xiangdong Chen, Xiangdong Chen, Yun Lin, Yun Lin, Yun Lin, Shanglong Yao, Shanglong Yao, Shanglong Yao   +20 more
doaj   +1 more source

Is lower-dose sugammadex a cost-saving strategy for reversal of deep neuromuscular block? Facts and fiction

BMC Anesthesiology, 2018
Background Sugammadex, a γ-cyclodextrin derivative, belongs to a new class of selective relaxant binding agents. Sugammadex was approved 10-years ago by the European medicines agency and today is used in clinical anesthesia and emergency medicine ...
Hans D de Boer, Ricardo V Carlos, Sorin J Brull   +2 more
doaj   +1 more source

Isolated forearm technique: a meta-analysis of connected consciousness during different general anaesthesia regimens [PDF]

, 2018
BACKGROUND: General anaesthesia should prevent patients from experiencing surgery, defined as connected consciousness. The isolated forearm technique (IFT) is the current gold standard for connected consciousness monitoring.
Carron, Michele, Linassi, Federico, Ori, Carlo, Tellaroli, Paola, Zanatta, P   +4 more
core   +1 more source

Factors that affect the onset of action of non-depolarizing neuromuscular blocking agents [PDF]

Korean Journal of Anesthesiology, 2017
Neuromuscular blockade plays an important role in the safe management of patient airways, surgical field improvement, and respiratory care. Rapid-sequence induction of anesthesia is indispensable to emergency surgery and obstetric anesthesia, and its ...
Yong Byum Kim, Tae-Yun Sung, Hong Seuk Yang   +2 more
doaj   +1 more source

Methods for Clinical Monitoring of Neuromuscular Transmission in Anesthesiology – A Review

International Journal of General Medicine
The administration of general anesthesia is a crucial aspect of surgery. However, it can pose significant risks to patients, such as respiratory depression and prolonged neuromuscular blockade.
Paweł Radkowski, Agnieszka Barańska, M. Mieszkowski, Justyna Dawidowska-Fidrych, K. Podhorodecka   +4 more
semanticscholar   +1 more source

Neuromuscular monitoring during anesthesia [PDF]

, 2007
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Open í sviðinuObjective: Muscle relaxants are very important in anesthetic practice but must be used with great care.
Erla G. Sveinsdóttir, Kristinn Sigvaldason   +1 more
core  

Compound Heterozygous MRPS14 Variants Associated With Leigh Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT MRPS14 (uS14m) is a nuclear‐encoded ribosomal protein important for mitochondria‐specific translation. To date, only a single individual with a recessive MRPS14‐related disorder (also known as COXPD38) has been reported. We report an additional subject possessing novel compound heterozygous MRPS14 variants (p.Asp37Asn, p.Asn60Asp). The subject
Maria Gabriela Otero, Christina Freeman, Ruchi Shah, Renkui Bai, Hong Cui, Marian Castro, Zachary Myers, Eric Choy, Derek Chan, Molly Easter, Sophia Y. Zhao, Madeline Babros, Ruchi Garg, Matthew Deardorff, Franklin Moser, Tyler Mark Pierson   +15 more
wiley   +1 more source

Deep Neuromuscular Blockade During General Anesthesia: Advantages, Challenges, and Future Directions

Anesthesia Research
Background: Neuromuscular blocking agents play an important role in modern anesthesia by facilitating optimal surgical conditions through deep muscle relaxation.
Jacob Rosenberg, Thomas Fuchs-Buder
doaj   +1 more source

The TREAT-NMD advisory committee for therapeutics (TACT): an innovative de-risking model to foster orphan drug development [PDF]

, 2015
Despite multiple publications on potential therapies for neuromuscular diseases (NMD) in cell and animal models only a handful reach clinical trials. The ability to prioritise drug development according to objective criteria is particularly critical in ...
Allen, Hugh, Bourke, John, Burghes, Arthur, Bushby, Kate, Buyse, Gunnar, Caizergues, Didier, Catlin, Nick, Clemens, Paula, Cnaan, Avital, Comi, Giacomo, Connor, Edward, Csimma, Cristina, Day, Simon, de Luca, Annamaria, de Montleau, Béatrice, de Visser, Marianne, Dittrich, Sven, Dubrosky, Alberto, Eagle, Michelle, Finkel, Richard, Fishbeck, Kenneth, Flanigan, Kevin M., Furlong, Patricia, Grounds, Miranda, Hauschke, Dieter, Heslop, Emma, Hesterlee, Sharon, Hoffman, Eric, Irwin, Joseph, Jarecki, Jill, Kaufmann, Petra, Kelly, Michael, Korinthenberg, Rudolf, Laforêt, Pascal, Larkindale, Jane, Lovering, Richard, Mayer, Henry, McCall, John, McDonald, Robert, McNally, Elizabeth, McNeil, Dawn Elizabeth, McNeil, Elizabeth, Mendell, Jerry, Miller, Debra, Nagaraju, Kanneboyina, North, Kathryn, Ouillade, Marie-Christine, Straub, Volker, Wagner, Kathryn R., Wells, Dominic J.   +49 more
core   +4 more sources