Results 71 to 80 of about 4,079,393 (363)

Is lower-dose sugammadex a cost-saving strategy for reversal of deep neuromuscular block? Facts and fiction

BMC Anesthesiology, 2018
Background Sugammadex, a γ-cyclodextrin derivative, belongs to a new class of selective relaxant binding agents. Sugammadex was approved 10-years ago by the European medicines agency and today is used in clinical anesthesia and emergency medicine ...
Hans D de Boer, Ricardo V Carlos, Sorin J Brull   +2 more
doaj   +1 more source

Neuromuscular monitoring and its importance in neuromuscular blockade☆

Colombian Journal of Anesthesiology, 2012
Introduction: The incorporation of new guidelines or strategies as part of good practices in the use of muscle relaxants is not a requirement at present in the practice of anesthesia. There are only action recommendations designed to persuade clinicians of the fact that neuromuscular monitoring is a very useful tool for the rational use of muscle ...
Fabregat López, Joaquín, Candia Arana, César Augusto, Castillo Monzón, Caridad Greta   +2 more
openaire   +1 more source

Neurohormonal modulation of the Limulus heart: amine actions on neuromuscular transmission and cardiac muscle [PDF]

, 1985
The responses of Limulus cardiac neuromuscular junctions and cardiac muscle cells to four endogenous amines were determined in order to identify the cellular targets underlying amine modulation of heartbeat amplitude.
Augustine, George J., Colburne, J., Hoshi, T., Watson, Winsor H., III   +3 more
core   +1 more source

Improving translational studies: lessons from rare neuromuscular diseases [PDF]

, 2015
Animal models play a key role in the development of novel treatments for human disease. This is particularly true for rare diseases – defined as disorders that affect less than 1 in 2000 people in the human population – for which, very often, there are ...
Wells, D J
core   +3 more sources

Methods for Clinical Monitoring of Neuromuscular Transmission in Anesthesiology – A Review

International Journal of General Medicine
The administration of general anesthesia is a crucial aspect of surgery. However, it can pose significant risks to patients, such as respiratory depression and prolonged neuromuscular blockade.
Paweł Radkowski, Agnieszka Barańska, M. Mieszkowski, Justyna Dawidowska-Fidrych, K. Podhorodecka   +4 more
semanticscholar   +1 more source

Neuromuscular Monitoring: Keep It Simple!

Anesthesia and Analgesia, 2019
The proposals by Biro et al, 1 which appear in this month’s “Open Mind,” address the future of perioperative neuromuscular monitoring. In essence, their article is an “opinion piece,” which clearly was well received by the peer-review experts of this ...
M. Naguib, A. Kopman
semanticscholar   +1 more source

Reduced Muscular Carnosine in Proximal Myotonic Myopathy—A Pilot 1H‐MRS Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Alexander Gussew, Maryam Kargaran, Maik Rothe, Andreas Deistung, Dietrich Stoevesandt, Walter A. Wohlgemuth, David Strube, Thomas Kendzierski, Anna Katharina Kölsch, Maurits Gerhard Abraham Heuschen, Markus Otto, Alexander Mensch   +11 more
wiley   +1 more source

Diaphragm ultrasonography as a monitor in assessing antagonistic effect of sugammadex on rocuronium in patients with Child-Pugh grades A and B

Frontiers in Medicine
BackgroundAlthough diaphragm ultrasound can be used for detecting residual neuromuscular blockade post-surgery, there exists notable dearth in contemporary research exploring the correlation between preoperative Child-Pugh classification and the ...
Yan Sun, Yan Sun, Yan Sun, Shujun Sun, Shujun Sun, Shujun Sun, Rui Chen, Rui Chen, Rui Chen, Jiwei Shen, Jiwei Shen, Jiwei Shen, Xiangdong Chen, Xiangdong Chen, Xiangdong Chen, Yun Lin, Yun Lin, Yun Lin, Shanglong Yao, Shanglong Yao, Shanglong Yao   +20 more
doaj   +1 more source

Falsely increased Bispectral Index™ due to neuromuscular transmission monitoring [PDF]

, 2023
Vasyl Katerenchuk, A. Calçada, Antônio Carlos Batista, Lisa Cordeiro   +3 more
openalex   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source