Results 41 to 50 of about 32,201 (250)

Immunotherapy of Neuromyelitis Optica [PDF]

open access: yesAutoimmune Diseases, 2013
Neuromyelitis optica (NMO) is a chronic inflammatory disease of the central nervous system that affects the optic nerves and spinal cord resulting in visual impairment and myelopathy. There is a growing body of evidence that immunotherapeutic agents targeting T and B cell functions, as well as active elimination of proinflammatory molecules from the ...
Benjamin Bienia, Roumen Balabanov
openaire   +3 more sources

Low-Density Granulocytes Are a Novel Immunopathological Feature in Both Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder [PDF]

open access: yes, 2019
Objective: To investigate whether low-density granulocytes (LDGs) are an immunophenotypic feature of patients with multiple sclerosis (MS) or neuromyelitis optica spectrum disorder (NMOSD).
Alexander, Tobias   +11 more
core   +3 more sources

The efficacy of rituximab in the therapy of neuromyelitis optica in a patient with Sjogren's syndrome: case-report and literature review [PDF]

open access: yesТерапевтический архив, 2018
This case is the first description of the successful anti-B-cell therapy with rituximab in a patient with Sjogrenʼs syndrome and neuromyelitis optica spectrum disorder in Russia.
A V Torgashina, V I Vasilyev
doaj   +1 more source

Imaging markers of disability in aquaporin-4 immunoglobulin G seropositive neuromyelitis optica: a graph theory study [PDF]

open access: yes, 2019
Neuromyelitis optica spectrum disorders lack imaging biomarkers associated with disease course and supporting prognosis. This complex and heterogeneous set of disorders affects many regions of the central nervous system, including the spinal cord and ...
Asseyer, Susanna   +10 more
core   +2 more sources

The Treatment of Neuromyelitis Optica [PDF]

open access: yesJournal of Neuro-Ophthalmology, 2014
Neuromyelitis optica (NMO) is an autoimmune disorder of the central nervous system directed against astrocytes. Initially diagnosed in individuals with monophasic or relapsing optic neuritis and transverse myelitis, NMO is now recognized as a demyelinating disorder with pleiotropic presentations due to the identification of a specific autoantibody ...
Jeffrey Bennett   +2 more
openaire   +2 more sources

Pacientes com neuromielite óptica apresentam doença mais incapacitante que pacientes com esclerose múltipla, incluindo maior chance de falecerem de uma doença desmielinizante [PDF]

open access: yes, 2013
Although neuromyelitis optica (NMO) is known to be a more severe disease than relapsing-remitting multiple sclerosis (RRMS), few studies comparing both conditions in a single center have been done.Methods: Comparison of our previously published cohort of
Bichuetti, Denis Bernardi   +4 more
core   +6 more sources

Biomarkers for neuromyelitis optica: a visual analysis of emerging research trends

open access: yesNeural Regeneration Research
Neuromyelitis optica is an inflammatory demyelinating disease of the central nervous system that differs from multiple sclerosis. Over the past 20 years, the search for biomarkers for neuromyelitis optica has been ongoing.
Xiangjun Li   +6 more
doaj   +1 more source

Neuromyelitis optica spectrum disorder with increased aquaporin-4 microparticles prior to autoantibodies in cerebrospinal fluid: a case report

open access: yesJournal of Medical Case Reports, 2019
Background Neuromyelitis optica spectrum disorders are severe autoimmune inflammatory diseases of the central nervous system associated with the presence of immunoglobulin G antibodies against the water channel protein aquaporin-4.
Susanne Bejerot   +6 more
doaj   +1 more source

Electrical muscle stimulation intervention in the acute phase of neuromyelitis optica: Two case reports

open access: yesSAGE Open Medical Case Reports, 2020
The aim of this study was to examine the effect of electrical muscle stimulation on muscle atrophy caused by neuromyelitis optica. Two neuromyelitis optica patients with flaccid paralysis participated.
Kana Michiue, Yuichi Nishikawa
doaj   +1 more source

Neuromyelitis Optica in a Nepalese Man

open access: yesCase Reports in Neurological Medicine, 2017
Background. Neuromyelitis optica is a severely disabling inflammatory disorder of the central nervous system of autoimmune etiology that mainly affects the optic nerves and spinal cord. Here, we present a case report detailing a patient with tingling and
Yogesh Subedi   +4 more
doaj   +1 more source

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