Results 91 to 100 of about 16,378 (224)
Neuromyelitis optica spectrum disorder: a pediatric case report
Medicine Science, 2017 Neuromyelitis optica spectrum disorder(NMOSD) is an autoimmune demyelinating disorder of the central nervous system that predominantly affects the optic nerves and the spinal cord.
Mujgan Arslan +3 more
doaj +1 more source
Serum neurofilament light chain levels at attack predict post-attack disability worsening and are mitigated by inebilizumab: analysis of four potential biomarkers in neuromyelitis optica spectrum disorder [PDF]
, 2023 Orhan Aktaş +17 more
openalex +1 more source
Experimental mouse model of optic neuritis with inflammatory demyelination produced by passive transfer of neuromyelitis optica-immunoglobulin G. [PDF]
, 2014 Background Although optic neuritis (ON) is a defining feature of neuromyelitis optica (NMO), appropriate animal models of NMO ON are lacking. Most NMO patients are seropositive for immunoglobulin G autoantibodies (NMO-IgG) against the astrocyte water ...
Asavapanumas, N +6 more
core +2 more sources
CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.Astrocyte‐derived CHI3L1 is elevated in both a mouse model and pediatric patients with anti‐NMDAR encephalitis, coinciding with impaired hippocampal neurogenesis and cognitive deficits. CHI3L1 may serve as a potential biomarker for long‐term cognitive dysfunction in anti‐NMDAR encephalitis. ABSTRACT Background Anti‐N‐methyl‐D‐aspartate receptor (NMDAR)
Yuhang Li +11 more
wiley +1 more source
Aquaporin modulators: a patent review (2010-2015) [PDF]
, 2016 Introduction: Since the discovery of aquaporin-1 (AQP1) as a water channel, more than 2,000 articles, reviews and chapters have been published.
Casini, Angela, Soveral, Graça
core +1 more source
Nano Select, Volume 7, Issue 1, January 2026.Nanoparticle‐driven nose‐to‐brain drug delivery offers a noninvasive approach to bypass the blood–brain barrier (BBB) and directly modulate reactive astrocytes in CNS disorders. This review highlights biodegradable nanoparticles for astrocyte modulation, enhancing drug bioavailability, sustained release, and neuroinflammation control.
Senamile M. Dlamini +3 more
wiley +1 more source
Nature Communications, 2020 Type I IFN has apposing effects in neuromyelitis optica spectrum disorder (NMOSD) and multiple sclerosis (MS). Here the authors perform molecular profiling of NMOSD patients and mouse mechanistic experiments of neuro-inflammation to show that IFN-I ...
Agnieshka M. Agasing +13 more
doaj +1 more source
Cerebrospinal fluid aquaporin-4-immunoglobulin G disrupts blood brain barrier [PDF]
, 2015 To clarify the significance of immunoglobulin G autoantibody specific for the astrocyte water channel aquaporin-4 in cerebrospinal fluid, aquaporin-4-immunoglobulin G from a neuromyelitis optica patient was administered intrathecally to naïve mice, and ...
Asgari, Nasrin +4 more
core +2 more sources
Immunopathological Effects Of Aquaporin-4 Ig G In Neuromyelitis Optica Spectrum Disorders [PDF]
, 2017 published_or_final_versio
Chan, KH, Ng, CL, Yick, LW
core +1 more source