Results 21 to 30 of about 6,482 (100)

MOG Antibody‐Associated Optic Neuritis Masquerading as Traumatic Optic Neuropathy Following Cranial Trauma: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) is an autoimmune disorder characterized by demyelination of the central nervous system. It can impact the optic nerves, spinal cord, brain parenchyma, and brainstem, resulting in various clinical presentations such as acute disseminated encephalomyelitis (ADEM), optic ...
Yuxian Shi   +5 more
wiley   +1 more source

Optic Neuritis in the Puerperium Mimicking Severe Preeclampsia: A Neurological Differential Diagnosis in the Obstetric Emergency Setting

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Optic neuritis is an acute inflammatory disease that can cause acute visual loss. We present a case of a 22‐year‐old female in postpartum with acute headache, retroocular pain, and bilateral amaurosis. Orbit MRI revealed inflammatory changes in both neurovascular optical bundles.
Jose Luis Rojas‐Oviedo   +5 more
wiley   +1 more source

Neuromyelitis Optica Spectrum Disorder Following Pituitary Tumor Resection: A Rare but Critical Differential in Neurosurgical Practice

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Neuromyelitis optica spectrum disorder (NMOSD) is a rare, immune‐mediated astrocytopathy disorder that predominantly affects adults. Postoperative cases are scarcely reported. A 75‐year‐old woman underwent uncomplicated endoscopic resection of a nonfunctional pituitary macro‐adenoma.
Arad Iranmehr   +6 more
wiley   +1 more source

Synergistic Interaction Between MALAT1/miR‐30b‐5p/BAFF Axis and Inflammatory Cytokines Underlies Rituximab‐Refractory NMOSD

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
The MALAT1/miR‐30b‐5p/BAFF axis is activated in monocytes during NMOSD onset and relapse. The MALAT1/miR‐30b‐5p/BAFF axis is activated in monocytes, thereby facilitating the release of BAFF and inflammatory cytokines (including IL‐1, IL‐6, IL‐8, and TNF‐α).
Meiqun Deng   +8 more
wiley   +1 more source

Shifting From Systemic to Precision‐Targeted Complement Therapies: Opportunities and Hurdles

open access: yesEuropean Journal of Immunology, Volume 56, Issue 6, June 2026.
Complement therapeutics have expanded considerably, but systemic inhibitors remain limited by infection risks, breakthrough events, and loss of physiological functions. Emerging targeted approaches aim for organ‐, tissue‐, or cell‐specific modulation of complement activity, potentially offering greater precision while reducing treatment burden and ...
Marco Mannes   +2 more
wiley   +1 more source

Multifaceted Role of Extracellular Vesicles: Intercellular Messengers to Therapeutic Applications: A Narrative Review

open access: yesHealth Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims Extracellular vesicles (EVs) are nanoscale carriers, including exosomes, microvesicles, and apoptotic bodies, that mediate intercellular communication by transporting proteins, nucleic acids, lipids, and metabolites. They regulate immunity, tissue repair, and cell differentiation.
Kajal Kamra   +7 more
wiley   +1 more source

Pediatric Therapeutic Plasma Exchange: Characterization of Practice, Epidemiology, and Safety Profile at a Children's Hospital in the United States

open access: yesJournal of Clinical Apheresis, Volume 41, Issue 3, June 2026.
ABSTRACT There is a need to better understand the indications and safety profiles for therapeutic plasma exchange (TPE) in children. We aimed to assess pediatric TPE practice at a large academic center by retrospective chart review from 2011 to 2022. Patient demographics and clinical information including American Society for Apheresis (ASFA) category ...
Benjamin C. Lee   +4 more
wiley   +1 more source

The Association Between MOG‐IgG Positivity and mRNA SARS‐CoV‐2 Vaccination in Denmark: A Self‐Controlled Case Series Study

open access: yesPharmacoepidemiology and Drug Safety, Volume 35, Issue 6, June 2026.
ABSTRACT Purpose Spontaneous reporting of a possible link between myelin oligodendrocyte glycoprotein (MOG) antibody‐associated disease (MOGAD) and mRNA SARS‐CoV‐2 vaccination warrants further examination. Hence, the objective of this study was to investigate the association between MOG‐IgG positivity as a proxy for MOGAD and mRNA SARS‐CoV‐2 ...
Tine Iskov Kopp   +9 more
wiley   +1 more source

Differences in Income Growth Between People With Multiple Sclerosis and Controls: A Norwegian Cohort Study

open access: yesEuropean Journal of Neurology, Volume 33, Issue 6, June 2026.
Income growth was significantly lower for people with MS compared to controls, and men with MS lost income at a younger age than women with MS (49 vs. 55 years). Men also lost income earlier in the disease course than women (2 vs. 5 years post‐diagnosis).
Anne Høgset   +6 more
wiley   +1 more source

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