Results 21 to 30 of about 6,482 (100)
ABSTRACT Myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) is an autoimmune disorder characterized by demyelination of the central nervous system. It can impact the optic nerves, spinal cord, brain parenchyma, and brainstem, resulting in various clinical presentations such as acute disseminated encephalomyelitis (ADEM), optic ...
Yuxian Shi +5 more
wiley +1 more source
ABSTRACT Optic neuritis is an acute inflammatory disease that can cause acute visual loss. We present a case of a 22‐year‐old female in postpartum with acute headache, retroocular pain, and bilateral amaurosis. Orbit MRI revealed inflammatory changes in both neurovascular optical bundles.
Jose Luis Rojas‐Oviedo +5 more
wiley +1 more source
ABSTRACT Neuromyelitis optica spectrum disorder (NMOSD) is a rare, immune‐mediated astrocytopathy disorder that predominantly affects adults. Postoperative cases are scarcely reported. A 75‐year‐old woman underwent uncomplicated endoscopic resection of a nonfunctional pituitary macro‐adenoma.
Arad Iranmehr +6 more
wiley +1 more source
The MALAT1/miR‐30b‐5p/BAFF axis is activated in monocytes during NMOSD onset and relapse. The MALAT1/miR‐30b‐5p/BAFF axis is activated in monocytes, thereby facilitating the release of BAFF and inflammatory cytokines (including IL‐1, IL‐6, IL‐8, and TNF‐α).
Meiqun Deng +8 more
wiley +1 more source
Shifting From Systemic to Precision‐Targeted Complement Therapies: Opportunities and Hurdles
Complement therapeutics have expanded considerably, but systemic inhibitors remain limited by infection risks, breakthrough events, and loss of physiological functions. Emerging targeted approaches aim for organ‐, tissue‐, or cell‐specific modulation of complement activity, potentially offering greater precision while reducing treatment burden and ...
Marco Mannes +2 more
wiley +1 more source
Annals of Clinical and Translational Neurology, Volume 13, Issue 6, Page 1303-1304, June 2026.
Lea Gerischer +3 more
wiley +1 more source
ABSTRACT Background and Aims Extracellular vesicles (EVs) are nanoscale carriers, including exosomes, microvesicles, and apoptotic bodies, that mediate intercellular communication by transporting proteins, nucleic acids, lipids, and metabolites. They regulate immunity, tissue repair, and cell differentiation.
Kajal Kamra +7 more
wiley +1 more source
ABSTRACT There is a need to better understand the indications and safety profiles for therapeutic plasma exchange (TPE) in children. We aimed to assess pediatric TPE practice at a large academic center by retrospective chart review from 2011 to 2022. Patient demographics and clinical information including American Society for Apheresis (ASFA) category ...
Benjamin C. Lee +4 more
wiley +1 more source
ABSTRACT Purpose Spontaneous reporting of a possible link between myelin oligodendrocyte glycoprotein (MOG) antibody‐associated disease (MOGAD) and mRNA SARS‐CoV‐2 vaccination warrants further examination. Hence, the objective of this study was to investigate the association between MOG‐IgG positivity as a proxy for MOGAD and mRNA SARS‐CoV‐2 ...
Tine Iskov Kopp +9 more
wiley +1 more source
Income growth was significantly lower for people with MS compared to controls, and men with MS lost income at a younger age than women with MS (49 vs. 55 years). Men also lost income earlier in the disease course than women (2 vs. 5 years post‐diagnosis).
Anne Høgset +6 more
wiley +1 more source

