Results 31 to 40 of about 2,454,151 (187)

Evaluation of Dried Plasma Spot-Based Quantification of Glial Fibrillary Acidic Protein as a Disease-Associated Biomarker in Neuromyelitis Optica Spectrum Disorder. [PDF]

Ann Clin Transl Neurol
ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Wohlrab F, Alvarez E, Hamdi R, Zhang B, Ji H, Jhaveri N, Schindler P, Sanchez P, Sperber PS, Schmitz-Hübsch T, Oertel FC, Vorasoot N, Kissani N, Böhringer F, Kuhle J, Pröbstel AK, Ma XJ, Körtvelyessy P, Waters P, Paul F.   +19 more
europepmc   +2 more sources

Multiple sclerosis or neuromyelitis optica? Re-evaluating an 18th-century illness using 21st-century software. [PDF]

, 2012
In this paper we report the application of an extensive database of symptoms, signs, laboratory findings and illnesses, to the diagnosis of an historical figure.
Garrard, P, Peters, TJ
core   +1 more source

Severe optic neuritis in a patient with combined neuromyelitis optica spectrum disease and primary Sjögren’s syndrome: a case report

Journal of Medical Case Reports, 2012
Introduction Optic neuritis, although uncommon, can be the initial presentation of Sjögren’s syndrome. Coexisting Sjögren’s syndrome has also been reported with neuromyelitis optica spectrum disorder.
Tan Petrina, Yu Wai, Umapathi Thirugnanam, Lim Su-Ann   +3 more
doaj   +1 more source

Aquaporin-4-IgG Positive Neuromyelitis Optica Spectrum Disorder from Ethiopia: A Case Report [PDF]

, 2020
BACKGROUND: Neuromyelitis Optica spectrum disorder is an inflammatory disorder affecting the central nervous system), most commonly attacking the spinal cord or optic nerves. Limited cases of neuromyelitis optica have been reported in east Africa.
Dereje Melka
core   +1 more source

Case Report: Interferon-Alpha-Induced Neuromyelitis Optica Spectrum Disorder

Frontiers in Neurology, 2022
Background and ObjectivesTo describe a new case of neuromyelitis optica spectrum disorder (NMOSD) induced by the administration of interferon-alpha (IFNα) and to raise awareness of this rare drug-induced disease of IFNα treatment.MethodsA single case ...
Jie Rao, Na Xu, Jing Sun, Yan Li, Fangwang Fu   +4 more
doaj   +1 more source

Biomarkers for neuromyelitis optica: a visual analysis of emerging research trends

Neural Regeneration Research
Neuromyelitis optica is an inflammatory demyelinating disease of the central nervous system that differs from multiple sclerosis. Over the past 20 years, the search for biomarkers for neuromyelitis optica has been ongoing.
Xiangjun Li, Jiandong Zhang, Siqi Zhang, Shengling Shi, Yi’an Lu, Ying Leng, Chunyan Li   +6 more
doaj   +1 more source

Treating multiple sclerosis and neuromyelitis optica spectrum disorder during the COVID-19 pandemic

, 2020
The emergence of novel Coronavirus 2019 (COVID-19)1 and the subsequent pandemic present a unique challenge to Neurologists managing patients with multiple sclerosis (MS) and related neuroinflammatory disorders, such as neuromyelitis spectrum disorder ...
Killestein, J, Brownlee, Wallace, Broadley, Simon, Ciccarelli, Olga, Bourdette, Dennis, Brownlee, W, Ciccarelli, O, Killestein, Joep, Bourdette, D, Broadley, S   +9 more
core   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Neuromyelitis Optica Spectrum Disorder: A Case Report

Journal of Nepal Medical Association
Neuromyelitis optica spectrum disorder also known as Devic's disease is an autoimmune condition where the body produces antibodies against Aquaporin-4 in the astrocytes.
Prakriti Karki, Sagar Pahari, Nayan Neupane, Kushal Poudel, Nehal Asharaf   +4 more
doaj   +3 more sources

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source