Results 81 to 90 of about 16,378 (224)
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source
Neuromyelitis optica spectrum disorder in pediatrics. Case report
Introduction: Neuromyelitis optica is an inflammatory disorder of the central nervous system that accounts for 5% of demyelinating diseases in pediatrics.
Jhon Camacho +4 more
doaj +1 more source
Attack adjudication in neuromyelitis optica spectrum disorder: Substantiation of criteria by magnetic resonance imaging and biomarkers in N-MOmentum [PDF]
Brian G. Weinshenker +18 more
openalex +1 more source
ABSTRACT Background and Objectives Neuromyelitis optica spectrum disorder (NMOSD) is a chronic disorder with a relapsing–remitting disease course that impacts patients' quality of life. Oral glucocorticoids (OGCs) have been the standard of care for NMOSD in Japan; however, their chronic use is associated with adverse events (AEs).
Yuko Shimizu +7 more
wiley +1 more source
Neuromyelitis optica spectrum disorder-related optic neuritis (NMOSD-ON) is an autoimmune disease that affects the astrocytes. NMOSD-ON is one of the core clinical phenotypes of neuromyelitis optica spectrum disorder and its most-common initial symptom ...
Yao Qiu, Ting Shen, Wei Qiu, Hui Yang
doaj +1 more source
Recurrent longitudinally extensive transversal myelitis in a patient with Sjögren’s syndrome [PDF]
Introduction. Longitudinally extensive transverse myelitis (LETM) is a transversal myelitis that extends through three or more vertebral segments in length. Case report.
Gvozdenović Slobodan +7 more
core +1 more source
ABSTRACT Objectives Although satralizumab, an interleukin‐6 receptor inhibitor, effectively prevents relapses in neuromyelitis optica spectrum disorder (NMOSD), infections are reported to be the most common adverse reactions. To support Japanese patients receiving satralizumab, “Circle”—a 1‐year patient support program—was developed.
Kazuo Fujihara +3 more
wiley +1 more source
Functional characterization of reappearing B cells after anti-CD20 treatment of CNS autoimmune disease. [PDF]
The anti-CD20 antibody ocrelizumab, approved for treatment of multiple sclerosis, leads to rapid elimination of B cells from the blood. The extent of B cell depletion and kinetics of their recovery in different immune compartments is largely unknown ...
Bernard, Claude CA +9 more
core +1 more source
ABSTRACT Painful muscle spasms are characterized by sudden onset of involuntary muscle contractions accompanying severe pain. The occurrence of painful muscle spasms after total hip arthroplasty (THA) is extremely rare in clinical practice. We report a case in which a patient developed painful muscle spasms after THA, and symptoms were controlled by ...
Youhan Yang +3 more
wiley +1 more source
A Rare Case of Neuromyelitis Optica Spectrum Disorder in Patient with Sjogren’s Syndrome
We report a 48-year-old female with the history of Sjogren’s syndrome who presented with 3-week history of tingling, numbness, and shooting back, waist, and bilateral leg pain and numbness in the pelvic region with urinary and bowel incontinence ...
Supat Thongpooswan +2 more
doaj +1 more source

