Results 241 to 250 of about 9,342,488 (306)

Presymptomatic Amyotrophic Lateral Sclerosis: From Early Biomarker Detection to Phenoconversion Prediction. [PDF]

Diagnostics (Basel)
Chen M, Li H, Jin Q.
europepmc   +1 more source

Advances in Bio‐Integrated Edge Computing Systems for Smart and Connected Health

Advanced Materials, EarlyView.
This review explores advances in bio‐integrated edge computing for healthcare, focusing on co‐designing computing, sensing, and energy strategies to overcome integration and power challenges for optimized, decentralized operation. ABSTRACT Recent advances in bio‐integrated healthcare technologies have enabled continuous, high‐resolution monitoring and ...
Gyuwon Kim, Seungwon Yoo, Tae Woog Kang, Yunuo Huang, Woon‐Hong Yeo   +4 more
wiley   +1 more source

The TNKS/PI31-proteasome axis as a central node in TDP-43 neuropathies. [PDF]

J Biomed Sci
Bubphachat P, Majumder P, Wang IF, Huang JK, Kao TJ, Lee YC, Shen CJ, Chen GC, Chen PC, Huang CS.   +9 more
europepmc   +1 more source

Biomass DNA: An Emerging Building Block for Advanced Materials

Advanced Materials, EarlyView.
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley   +1 more source

Why are some neurons spared in neurodegeneration? Cellular subtype identity maintenance as a candidate threshold-setting mechanism. [PDF]

PLoS Biol
Kim DW.
europepmc   +1 more source

A Retinal Matrix Stiffening Model Reveals FAK‐Dependent Mechanotransduction in Pericytes Underlies Vascular Destabilization

Advanced Materials, EarlyView.
In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren, Alex Wu, Lucas Ramirez, Yaqing Huang, Connor Amelung, Sophia Saxonhouse, Sharon Gerecht   +6 more
wiley   +1 more source

Hyperfunction of PSD-95 leads to hyperexcitability and cognitive abnormalities in MEF2C haploinsufficiency. [PDF]

Proc Natl Acad Sci U S A
Pan M, Acharya A, Lee KY, Rhodes JS, Tsai NP.   +4 more
europepmc   +1 more source

LEM-3/ANKLE1 nuclease prevents the formation of abnormal syncytium to safeguard neuronal differentiation. [PDF]

PLoS Biol
Deng S, Zheng C.
europepmc   +1 more source

Exosomes: emerging biomarkers and therapeutic potential in postoperative delirium and postoperative cognitive dysfunction. [PDF]

Front Cell Dev Biol
Li X, Xu L, Song Q, Chu Q.
europepmc   +1 more source

Serotonergic Dysfunction and the Interacting Role of TAR DNA-Binding Protein 43 in the Progression of Amyotrophic Lateral Sclerosis: A Scoping Review. [PDF]

Biomolecules
Hutchison LL, Parkes MM, Pioro EP.
europepmc   +1 more source