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BBB dynamics: the lifespan perspective [PDF]
Scientific ReportsRecent advances have shifted our understanding of the blood–brain barrier (BBB) not as a static wall, but as a dynamic and evolving system whose property is variable across the lifespan: acquisitive in early development, heterogeneous in adulthood, and ...
Xuefang Sophie Ren
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Liver X Receptor as a Possible Drug Target for Blood-Brain Barrier Integrity [PDF]
Advanced Pharmaceutical Bulletin, 2022 Purpose: blood-brain barrier (BBB) is made of specialized cells that are responsible for theselective passage of substances directed to the brain. The integrated BBB is essential for precisecontrolling of the different substances passage as well as ...
Mahsa Eskandari, Ali Awsat Mellati
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Effect of Endurance Exercise and Methamphetamine Administration on the Expression of Blood-Brain Barrier Related Factors and BDNF in Hippocampus of Male Sprague-Dawley Rat [PDF]
운동과학, 2022 PURPOSE This study aimed to investigate the effect of short-term endurance exercise and methamphetamine administration on bloodbrain barrier (BBB)-related marker and brain-derived neurotrophic factor (BDNF) in the hippocampus of male Sprague-Dawley (SD ...
Su-Ryun Jung
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Developmental Cell, 2018 In this issue of Developmental Cell, Anbalagan et al. demonstrate that pituicytes, a subtype of astroglia, drive endothelial cell permeability in the zebrafish embryo neurohypophysis. This occurs via secretion of Vegfa/Tgfβ3 permeability factors that promote formation of fenestrae and the repression of anti-inflammatory retinoic acid signaling that ...
Thomas, Jean-Léon, Eichmann, Anne
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Triolein emulsion enhances temozolomide brain delivery: an experimental study in rats
Drug Delivery, 2021 Purpose To evaluate the enhancement of temozolomide (TMZ) delivery in the rat brain using a triolein emulsion. Materials and Methods Rats were divided into the five groups as following: group 1 (negative control), group 2 (treated with triolein emulsion ...
Won-Bae Seung +10 more
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On bornological semi-abelian algebras [PDF]
Categories and General Algebraic Structures with Applications, 2021 If $\Bbb T$ is a semi-abelian algebraic theory, we prove that the category ${\rm Born}^{\Bbb T}$ of bornological $\Bbb T$-algebras is homological with semi-direct products.
Francis Borceux, Maria Manuel Clementino
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Purinergic signaling: A gatekeeper of blood-brain barrier permeation
Frontiers in Pharmacology, 2023 This review outlined evidence that purinergic signaling is involved in the modulation of blood-brain barrier (BBB) permeability. The functional and structural integrity of the BBB is critical for maintaining the homeostasis of the brain microenvironment.
Yuemei Wang +6 more
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Applied Sciences, 2019 Managing blood cholesterol levels is important for the treatment and prevention of diabetes, cardiovascular disease, and obesity. An easy-to-use, portable cholesterol blood test could accelerate more frequent testing by patients and at-risk populations ...
Kyongsik Yun +3 more
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