Dynamic m<sup>6</sup>A Methylation in Neurodevelopmental and Neurodegenerative Disorders. [PDF]
Ngo AL +5 more
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Cross-disease LC-MS/MS plasma proteomics identifies reproducible shared and disease-enriched biomarker signatures in neurodegenerative disorders. [PDF]
Choi Y +9 more
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NeuN, a neuronal specific nuclear protein in vertebratesxs
Development, 1992ABSTRACT A battery of monoclonal antibodies (mAbs) against brain cell nuclei has been generated by repeated immunizations. One of these, mAb A60, recognizes a vertebrate nervous systemand neuron-specific nuclear protein that we have named NeuN (Neuronal Nuclei). The expression of NeuN is observed in most neuronal cell types throughout
R J, Mullen, C R, Buck, A M, Smith
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Intracellular dynamics of calcyon, a neuron-specific vesicular protein
NeuroReport, 2007Calcyon is a brain-specific protein, implicated in clathrin-mediated endocytosis. In this descriptive study we show that calcyon is exclusively expressed in neurons, and localized in moving vesicles. The movement of calcyon-containing vesicles was dependent on temperature and on intact microtubules, in addition these vesicles were colocalized with a ...
Markus, Kruusmägi +3 more
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Neuron-specific protein expression at striatal excitatory synapses
2023Abstract Combinatorial expression of postsynaptic proteins underlies synapse diversity within and between neuron types 1-5 . Thus, characterization of neuron-type-specific postsynaptic proteomes is key to obtaining a deeper understanding of discrete synaptic properties and how ...
Yi-Zhi Wang +3 more
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Human neurone-specific Hsj1 proteins
1997Abstract Human neurone-specific DnaJ-like proteins Hsj1 proteins were initially identified by immunoscreening an Alzheimer’s disease brain expression cDNA library using a polyclonal antiserum raised to a preparation of paired helical filaments (PHF), one of the pathological hallmarks of Alzheimer’s disease.
M E Cheetham, M Tighe
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Neuron specific protein (NSP) in neuroblastoma cells: Relation to differentiation
Brain Research, 1978The spectrum of enolase enzyme forms has been examined in several lines of neuroblastoma cells and compared to those present in whole brain. The neuron specific enolase (NSP) is greatly decreased in the cultured cells as judged by activity profiles and radioimmunoassay.
P J, Marangos +4 more
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Molecular Characterization of a Neuronal‐Specific Protein that Stimulates the Activity of Cdk5
Journal of Neurochemistry, 1995Abstract: Cyclin‐dependent kinase, Cdk5, has been identified in neural tissue in connection with neurofilament and τ protein phosphorylation. This report describes the characterization of a 62‐kDa protein that copurifies with Cdk5 from rat spinal cord homogenates.
K T, Shetty +7 more
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Neuron-specific enolase and neurofilament protein as markers of differentiation in medulloblastoma
Surgical Neurology, 1985Immunocytochemical localization of neuron-specific enolase was performed attempting evaluation for neuronal cell differentiation in medulloblastoma. Twenty-seven cases of human medulloblastomas were stained with anti-neuron-specific enolase and antineurofilament protein serum using the peroxidase-antiperoxidase technique.
M E, Velasco, M W, Ghobrial, E R, Ross
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