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The tree shrew, as a primate-like animal model, has been used for studying high brain functions such as social emotion and spatial learning memory. However, little is known about the excitatory synaptic transmission in cortical brain areas of the tree ...
Xu-Hui Li +5 more
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Neurons are highly polarized cells with structurally and functionally distinct processes called axons and dendrites. This polarization underlies the directional flow of information in the central nervous system, so the establishment and maintenance of neuronal polarization is crucial for correct development and function.
Tetsuya, Takano +4 more
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Neurons other than motor neurons in motor neuron disease.
Amyotrophic lateral sclerosis (ALS) is typically defined by a loss of motor neurons in the central nervous system. Accordingly, morphological analysis for decades considered motor neurons (in the cortex, brainstem and spinal cord) as the neuronal population selectively involved in ALS.
Ruffoli R +7 more
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Transcriptional Reprogramming of Distinct Peripheral Sensory Neuron Subtypes after Axonal Injury
Primary somatosensory neurons are specialized to transmit specific types of sensory information through differences in cell size, myelination, and the expression of distinct receptors and ion channels, which together define their transcriptional and ...
William Renthal +7 more
semanticscholar +1 more source
Spinocerebellar ataxia 3 (SCA3, also known as Machado–Joseph disease) is a neurodegenerative disease caused by inheritance of a CAG repeat expansion within the ATXN3 gene, resulting in polyglutamine (polyQ) repeat expansion within the ataxin-3 protein ...
Katherine J. Robinson +7 more
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21 pages, 32 figures. A preprint of a work submitted to a scientific journal (first revision)
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Excitatory synaptic transmission in central synapses is modulated by serotonin (5-HT). The anterior cingulate cortex (ACC) is an important cortical region for pain perception and emotion.
Zhen Tian +4 more
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An open-source tool for automated analysis of breathing behaviors in common marmosets and rodents
The respiratory system maintains homeostatic levels of oxygen (O2) and carbon dioxide (CO2) in the body through rapid and efficient regulation of breathing frequency and depth (tidal volume).
Mitchell Bishop +4 more
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Human iPSC co-culture model to investigate the interaction between microglia and motor neurons
Motor neuron diseases such as amyotrophic lateral sclerosis are primarily characterized by motor neuron degeneration with additional involvement of non-neuronal cells, in particular, microglia.
Björn F. Vahsen +13 more
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Dual roles of anterior cingulate cortex neurons in pain and pleasure in adult mice
Human and animal studies indicate that some brain regions are activated during painful and pleasant situations, such as the anterior cingulate cortex (ACC).
Jing-Shan Lu +4 more
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