Results 31 to 40 of about 1,209,467 (344)
21 pages, 32 figures. A preprint of a work submitted to a scientific journal (first revision)
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Neuronal progenitor cells (NPC) play an essential role in homeostasis of the central nervous system (CNS). Considering their ability to differentiate into specific lineages, their manipulation and control could have a major therapeutic impact for those ...
Matteo Manzati +3 more
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Human iPSC co-culture model to investigate the interaction between microglia and motor neurons
Motor neuron diseases such as amyotrophic lateral sclerosis are primarily characterized by motor neuron degeneration with additional involvement of non-neuronal cells, in particular, microglia.
Björn F. Vahsen +13 more
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Modeled channel distributions explain extracellular recordings from cultured neurons sealed to microelectrodes [PDF]
Amplitudes and shapes of extracellular recordings from single neurons cultured on a substrate embedded microelectrode depend not only on the volume conducting properties of the neuron-electrode interface, but might also depend on the distribution of ...
Buitenweg, Jan Reinoud +2 more
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Excitatory synaptic transmission in central synapses is modulated by serotonin (5-HT). The anterior cingulate cortex (ACC) is an important cortical region for pain perception and emotion.
Zhen Tian +4 more
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Neuron-Specific HuR-Deficient Mice Spontaneously Develop Motor Neuron Disease [PDF]
Human Ag R (HuR) is an RNA binding protein in the ELAVL protein family. To study the neuron-specific function of HuR, we generated inducible, neuron-specific HuR-deficient mice of both sexes.
Bai, Ying +10 more
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An open-source tool for automated analysis of breathing behaviors in common marmosets and rodents
The respiratory system maintains homeostatic levels of oxygen (O2) and carbon dioxide (CO2) in the body through rapid and efficient regulation of breathing frequency and depth (tidal volume).
Mitchell Bishop +4 more
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Leader neurons in leaky integrate and fire neural network simulations
Several experimental studies show the existence of leader neurons in population bursts of 2D living neural networks. A leader neuron is, basically, a neuron which fires at the beginning of a burst (respectively network spike) more often that we expect by
Zbinden, Cyrille
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Neurons other than motor neurons in motor neuron disease.
Amyotrophic lateral sclerosis (ALS) is typically defined by a loss of motor neurons in the central nervous system. Accordingly, morphological analysis for decades considered motor neurons (in the cortex, brainstem and spinal cord) as the neuronal population selectively involved in ALS.
Ruffoli R +7 more
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A compact aVLSI conductance-based silicon neuron
We present an analogue Very Large Scale Integration (aVLSI) implementation that uses first-order lowpass filters to implement a conductance-based silicon neuron for high-speed neuromorphic systems.
Hamilton, Tara Julia +4 more
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