Results 31 to 40 of about 458,086 (268)

Neurons other than motor neurons in motor neuron disease.

open access: yesHistology and histopathology, 2017
Amyotrophic lateral sclerosis (ALS) is typically defined by a loss of motor neurons in the central nervous system. Accordingly, morphological analysis for decades considered motor neurons (in the cortex, brainstem and spinal cord) as the neuronal population selectively involved in ALS.
Ruffoli R   +7 more
openaire   +5 more sources

Synaptic potentiation of anterior cingulate cortex contributes to chronic pain of Parkinson’s disease

open access: yesMolecular Brain, 2021
Parkinson’s disease (PD) is a multi-system neurodegenerative disorder. Patients with PD often suffer chronic pain. In the present study, we investigated motor, sensory and emotional changes in three different PD mice models.
Zhaoxiang Zhou   +13 more
doaj   +1 more source

Nucleolar reorganization after cellular stress is orchestrated by SMN shuttling between nuclear compartments

open access: yesNature Communications, 2023
Spinal muscular atrophy is an autosomal recessive neuromuscular disease caused by mutations in the multifunctional protein Survival of Motor Neuron, or SMN.
Shaqraa Musawi   +15 more
doaj   +1 more source

Flow cytometry allows rapid detection of protein aggregates in cellular and zebrafish models of spinocerebellar ataxia 3

open access: yesDisease Models & Mechanisms, 2021
Spinocerebellar ataxia 3 (SCA3, also known as Machado–Joseph disease) is a neurodegenerative disease caused by inheritance of a CAG repeat expansion within the ATXN3 gene, resulting in polyglutamine (polyQ) repeat expansion within the ataxin-3 protein ...
Katherine J. Robinson   +7 more
doaj   +1 more source

Multiset neurons

open access: yesPhysica A: Statistical Mechanics and its Applications, 2023
21 pages, 32 figures. A preprint of a work submitted to a scientific journal (first revision)
openaire   +3 more sources

Characterization of serotonin-induced inhibition of excitatory synaptic transmission in the anterior cingulate cortex

open access: yesMolecular Brain, 2017
Excitatory synaptic transmission in central synapses is modulated by serotonin (5-HT). The anterior cingulate cortex (ACC) is an important cortical region for pain perception and emotion.
Zhen Tian   +4 more
doaj   +1 more source

Dual roles of anterior cingulate cortex neurons in pain and pleasure in adult mice

open access: yesMolecular Brain, 2018
Human and animal studies indicate that some brain regions are activated during painful and pleasant situations, such as the anterior cingulate cortex (ACC).
Jing-Shan Lu   +4 more
doaj   +1 more source

Human iPSC co-culture model to investigate the interaction between microglia and motor neurons

open access: yesScientific Reports, 2022
Motor neuron diseases such as amyotrophic lateral sclerosis are primarily characterized by motor neuron degeneration with additional involvement of non-neuronal cells, in particular, microglia.
Björn F. Vahsen   +13 more
doaj   +1 more source

An open-source tool for automated analysis of breathing behaviors in common marmosets and rodents

open access: yeseLife, 2022
The respiratory system maintains homeostatic levels of oxygen (O2) and carbon dioxide (CO2) in the body through rapid and efficient regulation of breathing frequency and depth (tidal volume).
Mitchell Bishop   +4 more
doaj   +1 more source

The HIT Network for Children and Adolescents With CNS Tumors Facilitates Improvements of Diagnostic Assessments, Multimodal Treatments, Individual Counseling, and Research in Germany, Austria, and Switzerland

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background The HIT network was established in 2000 to create a population‐based structure aiming to improve survival rates and reduce late effects for children with central nervous system (CNS) tumors by conducting comprehensive clinical trials.
Stefan Rutkowski   +59 more
wiley   +1 more source

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