Results 41 to 50 of about 1,818,525 (389)
Neuron-Specific HuR-Deficient Mice Spontaneously Develop Motor Neuron Disease [PDF]
, 2018 Human Ag R (HuR) is an RNA binding protein in the ELAVL protein family. To study the neuron-specific function of HuR, we generated inducible, neuron-specific HuR-deficient mice of both sexes.
Bai, Ying +10 more
core +1 more source
Transcriptional Reprogramming of Distinct Peripheral Sensory Neuron Subtypes after Axonal Injury
Neuron, 2019 Primary somatosensory neurons are specialized to transmit specific types of sensory information through differences in cell size, myelination, and the expression of distinct receptors and ion channels, which together define their transcriptional and ...
William Renthal +7 more
semanticscholar +1 more source
Physica A: Statistical Mechanics and its Applications, 2023 21 pages, 32 figures. A preprint of a work submitted to a scientific journal (first revision)
openaire +2 more sources
Nature Communications, 2023 Spinal muscular atrophy is an autosomal recessive neuromuscular disease caused by mutations in the multifunctional protein Survival of Motor Neuron, or SMN.
Shaqraa Musawi +15 more
doaj +1 more source
Geometry-based finite-element modeling of the electrical contact between a cultured neuron and a microelectrode [PDF]
, 2003 The electrical contact between a substrate embedded microelectrode and a cultured neuron depends on the geometry of the neuron-electrode interface. Interpretation and improvement of these contacts requires proper modeling of all coupling mechanisms.
Buitenweg, Jan Reinoud +2 more
core +2 more sources
Disease Models & Mechanisms, 2021 Spinocerebellar ataxia 3 (SCA3, also known as Machado–Joseph disease) is a neurodegenerative disease caused by inheritance of a CAG repeat expansion within the ATXN3 gene, resulting in polyglutamine (polyQ) repeat expansion within the ataxin-3 protein ...
Katherine J. Robinson +7 more
doaj +1 more source
Leader neurons in leaky integrate and fire neural network simulations
, 2010 Several experimental studies show the existence of leader neurons in population bursts of 2D living neural networks. A leader neuron is, basically, a neuron which fires at the beginning of a burst (respectively network spike) more often that we expect by
Zbinden, Cyrille
core +1 more source
The Effect of a Refractory Period on the Power Spectrum of Neuronal Discharge [PDF]
, 1995 The interspike intervals in steady-state neuron firing are assumed to be independently and identically distributed random variables. In the simplest model discussed, each interval is assumed to be the sum of a random neuron refractory period and a ...
Bair, Wyeth, Franklin, Joel
core +2 more sources
Neurons other than motor neurons in motor neuron disease.
Histology and histopathology, 2017 Amyotrophic lateral sclerosis (ALS) is typically defined by a loss of motor neurons in the central nervous system. Accordingly, morphological analysis for decades considered motor neurons (in the cortex, brainstem and spinal cord) as the neuronal population selectively involved in ALS.
Ruffoli R +7 more
openaire +6 more sources