Results 51 to 60 of about 257,577 (143)
Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration
EMBO Molecular Medicine, 2015 Retinitis pigmentosa, caused predominantly by mutations in photoreceptor genes, currently lacks comprehensive treatment. We discover that retinal microglia contribute non‐cell autonomously to rod photoreceptor degeneration by primary phagocytosis of ...
Lian Zhao +9 more
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Inference based method for realignment of single trial neuronal responses [PDF]
arXiv, 2015 Neuronal responses to sensory stimuli or neuronal responses related to behaviour are often extracted by averaging neuronal activity over large number of experimental trials. Such trial-averaging is carried out to reduce noise and to reduce the influence of other signals unrelated to the corresponding stimulus or behaviour.
arxiv
The Regulatory Machinery of Neurodegeneration in In Vitro Models of Amyotrophic Lateral Sclerosis
Cell Reports, 2015 Neurodegenerative phenotypes reflect complex, time-dependent molecular processes whose elucidation may reveal neuronal class-specific therapeutic targets. The current focus in neurodegeneration has been on individual genes and pathways.
Burcin Ikiz +13 more
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Unsupervised learning by a nonlinear network with Hebbian excitatory and anti-Hebbian inhibitory neurons [PDF]
arXiv, 2018 This paper introduces a rate-based nonlinear neural network in which excitatory (E) neurons receive feedforward excitation from sensory (S) neurons, and inhibit each other through disynaptic pathways mediated by inhibitory (I) interneurons. Correlation-based plasticity of disynaptic inhibition serves to incompletely decorrelate E neuron activity ...
arxiv
Biology Open, 2013 Summary Amyotrophic Lateral Sclerosis (ALS) is a motor neuron degenerative disease characterized by a progressive, and ultimately fatal, muscle paralysis. The human VAMP-Associated Protein B (hVAPB) is the causative gene of ALS type 8.
Mario Sanhueza +3 more
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ON THE ROLE OF THE SPINAL AFFERENT NEURON AS A GENERATOR OF EXTRACELLULAR CURRENT [PDF]
, 1954 Donald O. Rudin, George Eisenman
openalex +1 more source
Neuron Platonic Intrinsic Representation From Dynamics Using Contrastive Learning [PDF]
arXivThe Platonic Representation Hypothesis suggests a universal, modality-independent reality representation behind different data modalities. Inspired by this, we view each neuron as a system and detect its multi-segment activity data under various peripheral conditions. We assume there's a time-invariant representation for the same neuron, reflecting its
arxiv
Subthreshold signal encoding in coupled FitzHugh-Nagumo neurons [PDF]
arXiv, 2017 Despite intensive research, the mechanisms underlying how neurons encode external inputs remain poorly understood. Recent work has focused on the response of a single neuron to a weak, subthreshold periodic signal. By simulating the FitzHugh-Nagumo stochastic model and then using a symbolic method to analyze the firing activity of the neuron, preferred
arxiv
"Reticular" and "Areticular" Nissl Bodies in Sympathetic Neurons of a Lizard [PDF]
, 1959 Stuart W. Smith
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Molecular BrainAdenylyl cyclase 1 (AC1) is a selective subtype of ACs, which is selectively expressed in neurons. The activation of AC1 is activity-dependent, and AC1 plays an important role in cortical excitation that contributes to chronic pain and related emotional ...
Wantong Shi +5 more
doaj +1 more source