Results 11 to 20 of about 5,245,598 (349)

Genetic deficiency of GABA differentially regulates respiratory and non-respiratory motor neuron development. [PDF]

open access: yesPLoS ONE, 2013
Central nervous system GABAergic and glycinergic synaptic activity switches from postsynaptic excitation to inhibition during the stage when motor neuron numbers are being reduced, and when synaptic connections are being established onto and by motor ...
Matthew J Fogarty   +5 more
doaj   +1 more source

Hyperexcitable Parvalbumin Interneurons Render Hippocampal Circuitry Vulnerable to Amyloid Beta

open access: yesiScience, 2020
Summary: Parvalbumin (PV) interneuron dysfunction is associated with various brain disorders, including Alzheimer disease (AD). Here, we asked whether early PV neuron hyperexcitability primes the hippocampus for amyloid beta-induced functional impairment.
Sara Hijazi   +5 more
doaj   +1 more source

Transient Response and Firing Behaviors of Memristive Neuron Circuit

open access: yesFrontiers in Neuroscience, 2022
The signal transmission mechanism of the Resistor-Capacitor (RC) circuit is similar to the intracellular and extracellular signal propagating mechanism of the neuron.
Xiaoyan Fang   +4 more
doaj   +1 more source

Neuron devices: emerging prospects in neural interfaces and recognition

open access: yesMicrosystems & Nanoengineering, 2022
Neuron interface devices can be used to explore the relationships between neuron firing and synaptic transmission, as well as to diagnose and treat neurological disorders, such as epilepsy and Alzheimer’s disease.
Yang Wang   +4 more
doaj   +1 more source

The prion-like transmission of tau oligomers via exosomes

open access: yesFrontiers in Aging Neuroscience, 2022
The conversion and transmission of misfolded proteins established the basis for the prion concept. Neurodegenerative diseases are considered “prion-like” disorders that lack infectivity.
Noel A. Jackson   +2 more
doaj   +1 more source

Disrupted Association of Sensory Neurons With Enveloping Satellite Glial Cells in Fragile X Mouse Model

open access: yesFrontiers in Molecular Neuroscience, 2022
Among most prevalent deficits in individuals with Fragile X syndrome (FXS) is hypersensitivity to sensory stimuli and somatosensory alterations. Whether dysfunction in peripheral sensory system contributes to these deficits remains poorly understood ...
Oshri Avraham   +7 more
doaj   +1 more source

Outdoor performance of a motion-sensitive neuron in the blowfly [PDF]

open access: yes, 2001
Egelhaaf M, Grewe J, Kern R, Warzecha A-K. Outdoor performance of a motion-sensitive neuron in the blowfly. Vision research. 2001;41(27):3627-3637.We studied an identified motion-sensitive neuron of the blowfly under outdoor conditions.
Egelhaaf, Martin   +9 more
core   +1 more source

Chemoconnectomics: Mapping Chemical Transmission in Drosophila.

open access: yesNeuron, 2019
We define the chemoconnectome (CCT) as the entire set of neurotransmitters, neuromodulators, neuropeptides, and their receptors underlying chemotransmission in an animal.
Bowen Deng   +11 more
semanticscholar   +1 more source

Behavioral simulation and synthesis of biological neuron systems using synthesizable VHDL [PDF]

open access: yes, 2011
Neurons are complex biological entities which form the basis of nervous systems. Insight can be gained into neuron behavior through the use of computer models and as a result many such models have been developed. However, there exists a trade-off between
Wilson, P.R.   +7 more
core   +1 more source

Glutamate-Releasing SWELL1 Channel in Astrocytes Modulates Synaptic Transmission and Promotes Brain Damage in Stroke

open access: yesNeuron, 2019
Summary By releasing glutamate, astrocytes actively regulate synaptic transmission and also contribute to excitotoxicity in neurological diseases. However, the mechanisms of astrocytic glutamate release have been debated.
Junhua Yang   +5 more
semanticscholar   +1 more source

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