Results 51 to 60 of about 5,245,598 (349)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Descending Control of Itch Transmission by the Serotonergic System via 5-HT1A-Facilitated GRP-GRPR Signaling

Neuron, 2014
SUMMARY Central serotonin (5-HT) modulates somatosensory transduction, but how it achieves sensory modality-specific modulation remains unclear. Here we report that enhancing serotonergic tone via administration of 5-hydroxytryptophan potentiates itch ...
Zhong-Qiu Zhao, Xian-Yu Liu, Joseph A. Jeffry, W. K. Ajith Karunarathne, Jin-Lian Li, Admire Munanairi, Xuan-Yi Zhou, Hui Li, Yan-Gang Sun, L. Wan, Zhen-Yu Wu, Seungil Kim, F. Huo, Ping Mo, Devin M. Barry, Chun-Kui Zhang, Ji-Young Kim, N. Gautam, K. Renner, Yun-Qing Li, Zhou-Feng Chen   +20 more
semanticscholar   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Dimensional reduction in networks of non-Markovian spiking neurons: Equivalence of synaptic filtering and heterogeneous propagation delays.

PLoS Computational Biology, 2019
Message passing between components of a distributed physical system is non-instantaneous and contributes to determine the time scales of the emerging collective dynamics.
Maurizio Mattia, Matteo Biggio, Andrea Galluzzi, Marco Storace   +3 more
doaj   +1 more source

TREM2 and microglia exosomes: a potential highway for pathological tau

Molecular Neurodegeneration, 2022
Tau pathology appears to spread along neuronal networks via the template misfolding of tau by pathological tau conformations. The mechanisms underlying neuron-to-neuron transmission of tau are unclear and recent work demonstrates a role for microglia in ...
Nimansha Jain, Jason D. Ulrich
doaj   +1 more source

Single-nucleus transcriptome analysis reveals transcriptional profiles of circadian clock and pain related genes in human and mouse trigeminal ganglion

Frontiers in Neuroscience, 2023
IntroductionClinical studies have revealed the existence of circadian rhythms in pain intensity and treatment response for chronic pain, including orofacial pain.
Yanhao Chu, Yanhao Chu, Yanhao Chu, Yaqi Wu, Yaqi Wu, Yaqi Wu, Shilin Jia, Shilin Jia, Shilin Jia, Ke Xu, Ke Xu, Ke Xu, Jinyue Liu, Jinyue Liu, Jinyue Liu, Lijia Mai, Lijia Mai, Lijia Mai, Wenguo Fan, Wenguo Fan, Wenguo Fan, Fang Huang, Fang Huang, Fang Huang   +23 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

BLOCKING OF WEAK SIGNAL PROPAGATION VIA AUTAPTIC TRANSMISSION IN SCALE-FREE NETWORKS

Electrica, 2019
In this paper, the effects of autapse, a kind of synapse formed between the axon or soma of a neuron and its own dendrite, on the transmission of weak signal are investigated in scale-free neuronal networks. In the study, we consider that each neuron has
Veli BAYSAL, Ergin YILMAZ, Mahmut ÖZER
doaj   +2 more sources

Spreading of Neurodegenerative Pathology via Neuron-to-Neuron Transmission of  -Amyloid [PDF]

Journal of Neuroscience, 2012
Alzheimer's disease (AD) is the major cause of dementia. During the development of AD, neurofibrillary tangles progress in a fixed pattern, starting in the transentorhinal cortex followed by the hippocampus and cortical areas. In contrast, the deposition of β-amyloid (Aβ) plaques, which are the other histological hallmark of AD, does not follow the ...
Sangeeta, Nath, Lotta, Agholme, Firoz Roshan, Kurudenkandy, Björn, Granseth, Jan, Marcusson, Martin, Hallbeck   +5 more
openaire   +2 more sources

Function of a Fly Motion-Sensitive Neuron Matches Eye Movements during Free Flight [PDF]

, 2005
Sensing is often implicitly assumed to be the passive acquisition of information. However, part of the sensory information is generated actively when animals move.
Roland Kern (108), J. H van Hateren (275094), Kern Roland, Lindemann Jens Peter, Egelhaaf Martin, Roland Kern, Jens Peter Lindemann, Christian Michaelis (110), Hateren, J.H. van, Hateren, J.H. van,, Martin Egelhaaf (112), Michaelis, Christian, Michaelis, Christian,, J. H. Van Hateren, Michaelis, C, Egelhaaf, Martin, van Hateren, JH, Kern, Roland,, Kern, Roland, Egelhaaf, Martin,, Jens Peter Lindemann (111), Michaelis Christian, Lindemann, Jens Peter ; https://orcid.org/, Lindemann, Jens Peter,, Lindemann, Jens Peter, Egelhaaf, Martin ; https://orcid.org/, Martin Egelhaaf, Kern, Roland ; https://orcid.org/, Christian Michaelis, J H van Hateren, van Hateren J. H   +30 more
core   +3 more sources