Results 61 to 70 of about 1,037,185 (302)

Overexpression of lncRNA TCTN2 protects neurons from apoptosis by enhancing cell autophagy in spinal cord injury

FEBS Open Bio, 2019
Neuronal apoptosis is the main pathological feature of spinal cord injury (SCI), while autophagy contributes to ameliorating neuronal damage via inhibition of apoptosis.
Xiao‐dong Ren, Chun‐xiao Wan, Ya‐li Niu   +2 more
doaj   +1 more source

Impact of aging : sporadic, and genetic risk factors on vulnerability to apoptosis in Alzheimer's disease [PDF]

, 2003
The identification of specific genetic (presenilin-1 [PS1] and amyloid precursor protein [APP] mutations) and environmental factors responsible for Alzheimer's disease (AD) has revealed evidence for a shared pathway of neuronal death.
Steiner, Barbara, Maurer, Konrad, Czech, Christian, Schindowski, Katharina, Leutner, Silke, Frölich, Lutz, Eckert, Anne, Pradier, Laurent, Kratzsch, Tilmann, Peters, Jürgen, Touchet, Natalie, Müller, Walter E.   +11 more
core  

Apoptosis Neuronal pada Penyakit Neurodegeneratif

, 2007
Abstrak Selama dekade terakhir, penelitian mengenai mekanisme apoptosis yang kompleks pada kerusakan sel saraf akut maupun kronik telah mengalami banyak kemajuan.
Sutanto, Sigit
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

CTL-Derived Granzyme B Participates in Hippocampal Neuronal Apoptosis Induced by Cardiac Arrest and Resuscitation in Rats

Frontiers in Neurology, 2019
Hippocampal neuronal apoptosis is a devastating consequence of cardiac arrest (CA) and subsequent cardiopulmonary resuscitation (CPR). In this study, we assessed the contribution of cytotoxic T lymphocyte (CTL)-derived toxic mediator granzyme B (Gra-b ...
Ning-Ning Ji, Liang Wu, Liang Wu, Bo-Ming Shao, Qing-Xiang Meng, Jin-Nan Xu, Hao-Wen Zhu, Yong-Mei Zhang, Yong-Mei Zhang   +8 more
doaj   +1 more source

An investigation into the mechanisms by which bim gene expression is regulated in sympathetic neurons [PDF]

, 2010
Neuronal apoptosis plays a critical role in development and disease. Developing sympathetic neurons require nerve growth factor (NGF) for their survival and die by apoptosis in its absence.
Hughes, R.
core  

Inhibition of apoptosis prevents West Nile virus induced cell death. [PDF]

, 2007
We found that WNV infection induces cell death in the brain-derived tumour cell line T98G by apoptosis under involvement of constituents of the extrinsic as well as the intrinsic apoptotic pathways.
Michaelis, Martin, Cinatl, Jindrich, Martin Michaelis, Hans-Wilhelm Doerr, Jindrich Cinatl, Henry Ogbomo, Kleinschmidt, Malte C, Ogbomo, Henry, Doerr, Hans Wilhelm, Malte C Kleinschmidt, Kleinschmidt, Malte Christian   +10 more
core   +1 more source

Developmental Attenuation of Neuronal Apoptosis by Neural-Specific Splicing of Bak1 Microexon. [PDF]

, 2020
Continuous neuronal survival is vital for mammals because mammalian brains have limited regeneration capability. After neurogenesis, suppression of apoptosis is needed to ensure a neurons long-term survival. Here we describe a robust genetic program that
Stoilov, Peter, Lin, Lin, Chen, Liang, Zhang, Min, Zheng, Sika   +4 more
core   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Neuronal MD2 induces long-term mental impairments in septic mice by facilitating necroptosis and apoptosis

Frontiers in Pharmacology, 2022
Sepsis-associated encephalopathy (SAE) is a complication of sepsis with high morbidity rates. Long-lasting mental health issues in patients with SAE result in a substantial decrease in quality of life.
Zhongmin Fan, Hongwei Ma, Yi Li, You Wu, Jiajia Wang, Lize Xiong, Lize Xiong, Zongping Fang, Xijing Zhang   +8 more
doaj   +1 more source