An exploration of feature vector design using neuronal region or neuronal object.
, 2022 The recognition model was trained on C1 by using KNN and neuronal density as a concatenated input vector and tested on various benchmarks, from which the mean accuracy was calculated.
Shang Wu (7497509) +6 more
core +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Neuronal density in hippocampal subfields of Ctrl, MTLE and TLE-TD groups.
, 2012 MTLE (dark gray boxplots) had reduced neuronal density (showed as thousands of cells per cubic millimeter), when compared to Ctrl (white boxplots) and TLE-TD (light gray boxplots), in granule cell layer (GCL), CA4, CA3, CA1 and prosubiculum, and in CA2 ...
Orfa Yineth Galvis-Alonso (135720) +8 more
core +1 more source
Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease
FEBS Letters, EarlyView.Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim +4 more
wiley +1 more source
Estimating neuronal connectivity from axonal and dendritic density fields
Frontiers in Computational Neuroscience, 2013 Neurons innervate space by extending axonal and dendritic arborizations. When axons and dendrites come in close proximity of each other, synapses between neurons can be formed.
Jaap evan Pelt, Arjen evan Ooyen
doaj +1 more source
BACKGROUND: Fractures related to osteoporosis and low bone mineral density lead to substantial morbidity, mortality, and cost to individuals and health systems.
GBD 2021 Low Bone Mineral Density Collaborators
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Neuronal density of the various groups of neurons in the functional territories of the striatum.
, 2013 A, stack bar graph showing the global interneuronal density. The colors of the stacks indicate different chemospecific subsets of neurons. B, stack bar showing the density (cells/mm3) of large, medium and small CR-ir interneurons.
Lucía Prensa (82917) +2 more
core +1 more source
A Two-Immunoglobulin-Domain Transmembrane Protein Mediates an Epidermal-Neuronal Interaction to Maintain Synapse Density [PDF]
, 2016 Synaptic maintenance is essential for neural circuit function. In the C. elegans locomotor circuit, motor neurons are in direct contact with the epidermis.
Jin, Yishi, Cherra, Salvatore J
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source