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Mental Retardation and Developmental Disabilities Research Reviews, 2001
AbstractNeuronal migration disorders are a category of developmental brain disorders leading to cortical dysplasia. This group of disorders is characterized by defective movement of neurons from the place of origin along the lining of the lateral ventricle, to the eventual place of residence in the correct laminar position within the cerebral cortex ...
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AbstractNeuronal migration disorders are a category of developmental brain disorders leading to cortical dysplasia. This group of disorders is characterized by defective movement of neurons from the place of origin along the lining of the lateral ventricle, to the eventual place of residence in the correct laminar position within the cerebral cortex ...
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Journal of Child Neurology, 2005
Improvement in imaging techniques has provided new classifications of neuronal migration disorders and their diagnosis in the developing or adult brain. Control of neuronal migration involves different cell populations, including Cajal-Retzius neurons, subplate neurons, neuronal precursors, or radial glia.
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Improvement in imaging techniques has provided new classifications of neuronal migration disorders and their diagnosis in the developing or adult brain. Control of neuronal migration involves different cell populations, including Cajal-Retzius neurons, subplate neurons, neuronal precursors, or radial glia.
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Neuronal growth cone migration
Experientia, 1990The neuronal growth cone is a semi-autonomous portion of the developing neuron that is highly specialized for motile activity. Migrating neurons may share some features with neuronal growth cones. I review some of what has been learned about growth cone initiation, the differentiation of axons and dendrites, the role of the cytoskeleton in motility ...
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Science Signaling, 2011
VEGF enhances NMDAR signaling to promote granule cell migration in the developing cerebellum.
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VEGF enhances NMDAR signaling to promote granule cell migration in the developing cerebellum.
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Neuritin 1 promotes neuronal migration
Brain Structure and Function, 2012Neuritin 1 (Nrn1 or cpg15-1) is an activity-dependent protein involved in synaptic plasticity during brain development, a process that relies upon neuronal migration. By analyzing Nrn1 expression, we found that it is highly expressed in a mouse model of migrating immortalized neurons (GN11 cells), but not in a mouse model of non-migrating neurons (GT1 ...
A. Zito +7 more
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Gonadotropin-Releasing Hormone Neuronal Migration
Seminars in Reproductive Medicine, 2007Neurons that synthesize and secrete the decapeptide gonadotropin-releasing hormone-1 (GnRH-1) to control the reproductive axis originate in the olfactory placode/vomeronasal organ of the olfactory system of mammals and migrate along vomeronasal nerves to the cribriform plate, which marks the boundary between the peripheral olfactory system and the ...
Schwarting, Gerald A. +2 more
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2006
Abstract During the development of the mammalian central nervous system (CNS), neurons are commonly generated at sites far from their final locations. They migrate to an anlage before differentiating into their final morphology and making synaptic connections.
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Abstract During the development of the mammalian central nervous system (CNS), neurons are commonly generated at sites far from their final locations. They migrate to an anlage before differentiating into their final morphology and making synaptic connections.
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Endocannabinoid signalling in neuronal migration
The International Journal of Biochemistry & Cell Biology, 2014The endocannabinoid (eCB) system consists of several endogenous lipids, their target CB1 and CB2 receptors and enzymes responsible for their synthesis and degradation. The most abundant eCB in the central nervous system (CNS), 2-arachidonoyl glycerol (2-AG), triggers a broad range of signalling events by acting on CB1, the most abundant G protein ...
Zhou, Ya +2 more
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Neuronal Migration Disorders in Man
European Journal of Morphology, 2000A classification of neuronal migration disorders based on the gross morphology of the disorder with subclassifications according to the cause of the underlying disorder as far as that is known is presented. Emphasis is on disorders of the neocortex.
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New Directions in Neuronal Migration
Science, 2002Over the past decade, genetic analyses have yielded a more molecular view of neuronal migration and its role in central nervous system development. We now realize that many of the molecular mechanisms that guide migrations in invertebrates are recapitulated in the vertebrate nervous system.
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