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The NEURON simulation program now allows Python to be used, alone or in combination with NEURON's traditional Hoc interpreter. Adding Python to NEURON has the immediate benefit of making available a very extensive suite of analysis tools written for engineering and science.
Hines, Michael L+2 more
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Creativity generates novel solutions to tasks by processing information. Imagination and mental representations are part of the creative process; we can mull over ideas of our own making, and construct algorithms or scenarios from them. Social scenario-building can be viewed as a human cognitive “super-power” that involves abstraction, meta ...
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Stochastic mechanism for improving selectivity of olfactory projection neurons [PDF]
A mechanism is proposed for increasing selectivity of olfactory bulb projection neurons as compared to the olfactory receptor neurons, which could operate under low odor concentration, when the lateral inhibition mechanism becomes inefficient. The mechanism proposed is based on the threshold-type reaction to stimuli a projection neuron receives from ...
arxiv +1 more source
Which Neurons Will Be the Engram - Activated Neurons and/or More Excitable Neurons? [PDF]
During past decades, the formation and storage principle of memory have received much attention in the neuroscience field. Although some studies have attempted to demonstrate the nature of the engram, elucidating the memory engram allocation mechanism was not possible because of the limitations of existing methods, which cannot specifically modulate ...
Ji-il Kim+3 more
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Error correction and fast detectors implemented by ultra-fast neuronal plasticity [PDF]
We experimentally show that the neuron functions as a precise time-integrator, where the accumulated changes in neuronal response latencies, under complex and random stimulation patterns, are solely a function of a global quantity, the average time-lag between stimulations.
arxiv +1 more source
Neuron-to-neuron α-synuclein propagation in vivo is independent of neuronal injury [PDF]
Interneuronal propagation of α-synuclein has been demonstrated in a variety of experimental models and may be involved in disease progression during the course of human synucleinopathies. The aim of this study was to assess the role that neuronal injury or, vice versa, cell integrity could have in facilitating interneuronal α-synuclein transfer and ...
Ulusoy, Ayse+6 more
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Two distinct desynchronization processes caused by lesions in globally coupled neurons [PDF]
To accomplish a task, the brain works like a synchronized neuronal network where all the involved neurons work together. When a lesion spreads in the brain, depending on its evolution, it can reach a significant portion of relevant area. As a consequence, a phase transition might occur: the neurons desynchronize and cannot perform a certain task ...
arxiv +1 more source
21 pages, 32 figures. A preprint of a work submitted to a scientific journal (first revision)
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Neurons other than motor neurons in motor neuron disease.
Amyotrophic lateral sclerosis (ALS) is typically defined by a loss of motor neurons in the central nervous system. Accordingly, morphological analysis for decades considered motor neurons (in the cortex, brainstem and spinal cord) as the neuronal population selectively involved in ALS.
Ruffoli R+7 more
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