Results 11 to 20 of about 2,597,556 (387)

Ghrelin Decreases Firing Activity of Gonadotropin-Releasing Hormone (GnRH) Neurons in an Estrous Cycle and Endocannabinoid Signaling Dependent Manner. [PDF]

, 2013
The orexigenic peptide, ghrelin is known to influence function of GnRH neurons, however, the direct effects of the hormone upon these neurons have not been explored, yet.
Farkas, Imre, Liposits, Zsolt, Sárvári, Miklós, Vastagh, Csaba   +3 more
core   +10 more sources

NEURON and Python [PDF]

Frontiers in Neuroinformatics, 2009
The NEURON simulation program now allows Python to be used, alone or in combination with NEURON's traditional Hoc interpreter. Adding Python to NEURON has the immediate benefit of making available a very extensive suite of analysis tools written for engineering and science.
Hines, Michael L, Davison, Andrew P., Muller, Eilif   +2 more
openaire   +4 more sources

Scientific Validation of Human Neurosphere Assays for Developmental Neurotoxicity Evaluation

Frontiers in Toxicology, 2022
There is a call for a paradigm shift in developmental neurotoxicity (DNT) evaluation, which demands the implementation of faster, more cost-efficient, and human-relevant test systems than current in vivo guideline studies.
Katharina Koch, Kristina Bartmann, Julia Hartmann, Julia Kapr, Jördis Klose, Eliška Kuchovská, Melanie Pahl, Kevin Schlüppmann, Etta Zühr, Ellen Fritsche, Ellen Fritsche   +10 more
doaj   +1 more source

Calcium Increase and Substance P Release Induced by the Neurotoxin Brevetoxin-1 in Sensory Neurons: Involvement of PAR2 Activation through Both Cathepsin S and Canonical Signaling

Cells, 2020
Red tides involving Karenia brevis expose humans to brevetoxins (PbTxs). Oral exposition triggers neurotoxic shellfish poisoning, whereas inhalation induces a respiratory syndrome and sensory disturbances.
Ophélie Pierre, Maxime Fouchard, Paul Buscaglia, Nelig Le Goux, Raphaël Leschiera, Olivier Mignen, Joachim W. Fluhr, Laurent Misery, Raphaële Le Garrec   +8 more
doaj   +1 more source

Machine Learning Identifies Cellular and Exosomal MicroRNA Signatures of Lyssavirus Infection in Human Stem Cell-Derived Neurons

Frontiers in Cellular and Infection Microbiology, 2021
Despite being vaccine preventable, rabies (lyssavirus) still has a significant impact on global mortality, disproportionally affecting children under 15 years of age.
Ryan J. Farr, Nathan Godde, Christopher Cowled, Vinod Sundaramoorthy, Diane Green, Cameron Stewart, John Bingham, Carmel M. O’Brien, Carmel M. O’Brien, Megan Dearnley   +9 more
doaj   +1 more source

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

Journal of Neuroscience, 2014
The major cell classes of the brain differ in their developmental processes, metabolism, signaling, and function. To better understand the functions and interactions of the cell types that comprise these classes, we acutely purified representative ...
Ye Zhang, Kenian Chen, S. Sloan, Mariko L. Bennett, A. Scholze, S. O’Keeffe, H. Phatnani, P. Guarnieri, Christine Caneda, N. Ruderisch, Shuyun Deng, S. A. Liddelow, Chaolin Zhang, R. Daneman, T. Maniatis, B. Barres, Jian Wu   +16 more
semanticscholar   +1 more source

TRPV1 and TRPA1 in cutaneous neurogenic and chronic inflammation: pro-inflammatory response induced by their activation and their sensitization

Protein & Cell, 2017
Cutaneous neurogenic inflammation (CNI) is inflammation that is induced (or enhanced) in the skin by the release of neuropeptides from sensory nerve endings. Clinical manifestations are mainly sensory and vascular disorders such as pruritus and erythema.
Olivier Gouin, Killian L’Herondelle, Nicolas Lebonvallet, Christelle Le Gall-Ianotto, Mehdi Sakka, Virginie Buhé, Emmanuelle Plée-Gautier, Jean-Luc Carré, Luc Lefeuvre, Laurent Misery, Raphaele Le Garrec   +10 more
doaj   +1 more source

Production of glycoprotein-deleted rabies viruses for monosynaptic tracing and high-level gene expression in neurons

Nature Protocols, 2010
Recombinant rabies viruses rendered replication-deficient by the deletion of their envelope glycoprotein gene are useful tools for neuroscientists, permitting (1) extraordinarily high transgene expression levels within neurons, (2) retrograde infection ...
Citation Wickersham, Ian R, Heather A Sullivan, H. Sebastian   +3 more
semanticscholar   +1 more source

Overexpression of Sox11 Promotes Corticospinal Tract Regeneration after Spinal Injury While Interfering with Functional Recovery [PDF]

, 2015
Embryonic neurons, peripheral neurons, and CNS neurons in zebrafish respond to axon injury by initiating pro-regenerative transcriptional programs that enable axons to extend, locate appropriate targets, and ultimately contribute to behavioral recovery ...
Blackmore, Murray G., Kirry, Adam, Nienhaus, Christopher, Reynolds, Ashley, Wang, Zimei   +4 more
core   +2 more sources

The Creative Neurons [PDF]

Frontiers in Psychology, 2021
Creativity generates novel solutions to tasks by processing information. Imagination and mental representations are part of the creative process; we can mull over ideas of our own making, and construct algorithms or scenarios from them. Social scenario-building can be viewed as a human cognitive “super-power” that involves abstraction, meta ...
openaire   +4 more sources