Results 41 to 50 of about 2,639,581 (370)
Neurons other than motor neurons in motor neuron disease.
Amyotrophic lateral sclerosis (ALS) is typically defined by a loss of motor neurons in the central nervous system. Accordingly, morphological analysis for decades considered motor neurons (in the cortex, brainstem and spinal cord) as the neuronal population selectively involved in ALS.
Ruffoli R+7 more
openaire +6 more sources
The Tumor Suppressor HHEX Inhibits Axon Growth when Prematurely Expressed in Developing Central Nervous System Neurons [PDF]
Neurons in the embryonic and peripheral nervoussystem respond to injury by activating transcriptional programs supportive of axon growth, ultimately resulting in functional recovery.
Blackmore, Murray G.+9 more
core +2 more sources
Studies have shown that exercise interventions can improve functional recovery after spinal cord injury, but the mechanism of action remains unclear. To investigate the mechanism, we established a unilateral corticospinal tract injury model in rats by ...
Ting-ting Hou+5 more
doaj +1 more source
Exciting inhibition in primates
A new genetic marker enables precise control over a group of inhibitory neurons in monkeys.
Wim Vanduffel, Xiaolian Li
doaj +1 more source
Post-transcriptional mechanisms play critical roles in the control of gene expression during neuronal development and maturation as they allow for faster responses to environmental cues and provide spatially-restricted compartments for local control of ...
Amy S. Gardiner+2 more
doaj +1 more source
The assembly of functional neuronal networks in the developing animal relies on the polarization of neurons, i.e., the formation of a single axon and multiple dendrites. Breaking the symmetry of neurons depends on cytoskeletal rearrangements. In particular, axon specification requires local dynamic instability of actin and stabilization of microtubules.
Tahirovic, S., Bradke, F.
openaire +3 more sources
Origins of choice-related activity in mouse somatosensory cortex. [PDF]
During perceptual decisions about faint or ambiguous sensory stimuli, even identical stimuli can produce different choices. Spike trains from sensory cortex neurons can predict trial-to-trial variability in choice.
Kwon, Sung E+3 more
core +2 more sources
Graphene-Derived Materials Interfacing the Spinal Cord: Outstanding in Vitro and in Vivo Findings
The attractiveness of graphene-derived materials (GDMs) for neural applications has fueled their exploration as components of biomaterial interfaces contacting the brain and the spinal cord.
Ana Domínguez-Bajo+6 more
doaj +1 more source
Responses of substantia gelatinosa neurons to putative neurotransmitters in an in vitro preparation of the adult rat spinal cord [PDF]
Extracellular recordings were performed from neurons of the substantia gelatinosa (SG) in an in vitro preparation obtained from the spinal cord of adult rats. About 40% of neurons were spontaneously active.
B. Sutor+29 more
core +1 more source
Lamina-specific AMPA receptor dynamics following visual deprivation in vivo. [PDF]
Regulation of AMPA receptor (AMPAR) expression is central to synaptic plasticity and brain function, but how these changes occur in vivo remains elusive.
Cudmore, Robert H+4 more
core +2 more sources