Results 41 to 50 of about 2,607,777 (388)
Single-protein detection in crowded molecular environments in cryo-EM images
eLife, 2017 We present an approach to study macromolecular assemblies by detecting component proteins’ characteristic high-resolution projection patterns, calculated from their known 3D structures, in single electron cryo-micrographs.
J Peter Rickgauer +2 more
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Coiled-Coil Motifs of RNA-Binding Proteins: Dynamicity in RNA Regulation
Frontiers in Cell and Developmental Biology, 2020 Neuronal granules are biomolecular condensates that concentrate high quantities of RNAs and RNA-related proteins within neurons. These dense packets of information are trafficked from the soma to distal sites rich in polysomes, where local protein ...
Lenzie K. Ford, Luana Fioriti
doaj +1 more source
The Tumor Suppressor HHEX Inhibits Axon Growth when Prematurely Expressed in Developing Central Nervous System Neurons [PDF]
, 2015 Neurons in the embryonic and peripheral nervoussystem respond to injury by activating transcriptional programs supportive of axon growth, ultimately resulting in functional recovery.
Blackmore, Murray G. +9 more
core +2 more sources
Frontiers in Behavioral Neuroscience, 2018 Deep brain stimulation (DBS) is a widely used treatment for neurodegenerative disorders like Parkinson’s disease. Recently, several studies have used preclinical animal models to suggest that DBS has a potential to improve emotional symptoms in mental ...
Yamini Bhaskar +2 more
doaj +1 more source
Neuroprotective Role of Akt in Hypoxia Adaptation in Andeans
Frontiers in Neuroscience, 2021 Chronic mountain sickness (CMS) is a disease that potentially threatens a large segment of high-altitude populations during extended living at altitudes above 2,500 m.
Helen Zhao +7 more
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Direct conversion of fibroblasts to functional neurons by defined factors
Nature, 2010 Cellular differentiation and lineage commitment are considered to be robust and irreversible processes during development. Recent work has shown that mouse and human fibroblasts can be reprogrammed to a pluripotent state with a combination of four ...
Thomas Vierbuchen +5 more
semanticscholar +1 more source
Healthy mitochondria for stroke cells
Brain Circulation, 2018 Stroke is a debilitating disease that remains as a significant unmet need. Although our understanding of the disease pathology has advanced over the years, treatment options for stroke are limited.
Eleonora Russo +2 more
doaj +1 more source
Cell Adhesion Molecules and Protein Synthesis Regulation in Neurons
Frontiers in Molecular Neuroscience, 2020 Cell adhesion molecules (CAMs) mediate interactions of neurons with the extracellular environment by forming adhesive bonds with CAMs on adjacent membranes or via binding to proteins of the extracellular matrix.
Irina Kozlova +5 more
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Responses of substantia gelatinosa neurons to putative neurotransmitters in an in vitro preparation of the adult rat spinal cord [PDF]
, 1983 Extracellular recordings were performed from neurons of the substantia gelatinosa (SG) in an in vitro preparation obtained from the spinal cord of adult rats. About 40% of neurons were spontaneously active.
B. Sutor +29 more
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