Results 41 to 50 of about 1,866,496 (373)
Identifying specific prefrontal neurons that contribute to autism-associated abnormalities in physiology and social behavior. [PDF]
, 2017 Functional imaging and gene expression studies both implicate the medial prefrontal cortex (mPFC), particularly deep-layer projection neurons, as a potential locus for autism pathology.
Brumback, AC +9 more
core +1 more source
Single-protein detection in crowded molecular environments in cryo-EM images
eLife, 2017 We present an approach to study macromolecular assemblies by detecting component proteins’ characteristic high-resolution projection patterns, calculated from their known 3D structures, in single electron cryo-micrographs.
J Peter Rickgauer +2 more
doaj +1 more source
Coiled-Coil Motifs of RNA-Binding Proteins: Dynamicity in RNA Regulation
Frontiers in Cell and Developmental Biology, 2020 Neuronal granules are biomolecular condensates that concentrate high quantities of RNAs and RNA-related proteins within neurons. These dense packets of information are trafficked from the soma to distal sites rich in polysomes, where local protein ...
Lenzie K. Ford, Luana Fioriti
doaj +1 more source
Frontiers in Behavioral Neuroscience, 2018 Deep brain stimulation (DBS) is a widely used treatment for neurodegenerative disorders like Parkinson’s disease. Recently, several studies have used preclinical animal models to suggest that DBS has a potential to improve emotional symptoms in mental ...
Yamini Bhaskar +2 more
doaj +1 more source
Neuroprotective Role of Akt in Hypoxia Adaptation in Andeans
Frontiers in Neuroscience, 2021 Chronic mountain sickness (CMS) is a disease that potentially threatens a large segment of high-altitude populations during extended living at altitudes above 2,500 m.
Helen Zhao +7 more
doaj +1 more source
Synaptophysin and synaptoporin expression in the developing rat olfactory system [PDF]
, 1993 The expressions of two closely related synaptic vesicle antigens synaptophysin and synaptoporin were examined in the olfactory system of the adult rat and during pre- and postnatal development.
Bayer +50 more
core +1 more source
Healthy mitochondria for stroke cells
Brain Circulation, 2018 Stroke is a debilitating disease that remains as a significant unmet need. Although our understanding of the disease pathology has advanced over the years, treatment options for stroke are limited.
Eleonora Russo +2 more
doaj +1 more source
Cell Adhesion Molecules and Protein Synthesis Regulation in Neurons
Frontiers in Molecular Neuroscience, 2020 Cell adhesion molecules (CAMs) mediate interactions of neurons with the extracellular environment by forming adhesive bonds with CAMs on adjacent membranes or via binding to proteins of the extracellular matrix.
Irina Kozlova +5 more
doaj +1 more source
Impact of adaptation currents on synchronization of coupled exponential integrate-and-fire neurons [PDF]
PLOS Computational Biology 8(4), e1002478 (2012), 2013 Author summary: Synchronization of neuronal spiking in the brain is related to cognitive functions, such as perception, attention, and memory. It is therefore important to determine which properties of neurons influence their collective behavior in a network and to understand how.
arxiv +1 more source