Results 141 to 150 of about 180,995 (352)

Contribution of Addictovigilance data to assess adverse‐events linked to psychoactive substances in children and adolescents

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims We sought to characterize adverse events and deaths associated with the use of psychoactive substances in children and adolescents. Methods Two French Addictovigilance databases were analysed: spontaneous reports and deaths over the period 2016–2021, in subjects aged 10–<18 years. An unsupervised classification was implemented on consumption data (
Hélène Peyrière   +13 more
wiley   +1 more source

Neuropathic pain evaluation tools

open access: yesRevista Dor
BACKGROUND AND OBJECTIVES: Pain is a subjective symptom which may be measured by means of its several features, such as intensity, quality, location, duration and impact on daily activities.
Fabiola Dach Eckeli   +2 more
doaj   +1 more source

Impact of diclofenac risk minimization measures addressing cardiovascular risk on analgesic use in musculoskeletal disorders

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims In 2013, risk minimization measures (RMMs) were introduced in Europe to address the increased cardiovascular risk linked to diclofenac. This study aimed to assess the impact of those RMMs on analgesic use. Methods Primary care data from CPRD GOLD (UK) were used.
Tomas Lasys   +5 more
wiley   +1 more source

Trends in analgesia prescribing in primary care in Ireland and England between 2014 and 2022: A repeated cross‐sectional study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Analgesic medicines are an important component of pain management, with different medicines carrying different risks and benefits. The aim of this study was to examine trends in analgesic prescribing in Ireland and England between 2014 and 2022. Methods Monthly data on medicines prescribed and dispensed in primary care were used. For Ireland, data
Molly Mattsson   +8 more
wiley   +1 more source

Combination vs. single‐drug nonprescription analgesics for acute pain management: A narrative review

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Combining nonprescription analgesics with different mechanisms of action has been proposed as a rational strategy to optimize the management of acute pain. This review assessed the efficacy and safety of nonprescription analgesics, including paracetamol (acetaminophen), metamizole and nonsteroidal anti‐inflammatory drugs (NSAIDs) used in combination vs.
Ali Mobasheri   +5 more
wiley   +1 more source

3D bioprinting in oral and craniomaxillofacial tissue regeneration: Progress, challenges, and future directions

open access: yesBMEMat, EarlyView.
This paper summarized the application of 3D bioprinting in the regeneration of various tissues in the oral and craniomaxillofacial fields, including the required biomaterials and printing techniques. Abstract Oral and craniomaxillofacial tissues are essential for maintaining oral functions, including respiration, mastication, swallowing, and speech ...
Huilu Zhan   +7 more
wiley   +1 more source

Cannabinoids From Trema micranthum (L.) Blume (Cannabaceae): A Cannabinoid Profiling System

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Trema micranthum (L.) Blume is a species from the Cannabaceae botanical family, present all over the tropics. A recent study conducted by our group identified the presence of cannabidiol (CBD), Δ9‐tetrahydrocannabinol, cannabidiolic acid, and tetrahydrocannabinolic acid‐A in T. micranthum extracts.
Yasmin Cunha‐Silva   +7 more
wiley   +1 more source

Volatilome and Antinociceptive Activity of the Traditional Preparation and Compounds from Ageratina grandifolia (Regel) R.M. King & H. Rob.

open access: yesChemistry &Biodiversity, EarlyView.
Abstract An infusion of Ageratina grandifolia, a traditional preparation, and major compounds [3,5‐diprenyl‐4‐hydroxyacetophenone (1), O‐methylencecalinol (2), encecalin (3), and encecalinol (4)], tested at 10, 31.6, and 100 mg/kg, intragastrically administered, showed a significant antinociceptive effect in both phases of the formalin test in mice ...
José Alberto Gutiérrez‐González   +5 more
wiley   +1 more source

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