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Neuropathic Pain in the Elderly [PDF]
Neuropathic pain due to a lesion or a disease of the somatosensory system often affects older people presenting several comorbidities. Moreover, elderly patients are often poly-medicated, hospitalized and treated in a nursing home with a growing risk of drug interaction and recurrent hospitalization. Neuropathic pain in the elderly has to be managed by
Roberto Bernabei+16 more
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Neuropathic pain is caused by a lesion or disease of the somatosensory system, including peripheral fibres (Aβ, Aδ and C fibres) and central neurons, and affects 7-10% of the general population. Multiple causes of neuropathic pain have been described and its incidence is likely to increase owing to the ageing global population, increased incidence of ...
Colloca+15 more
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Central neuropathic pain [PDF]
Central neuropathic pain arises from a lesion or disease of the central somatosensory nervous system such as brain injury, spinal cord injury, stroke, multiple sclerosis or related neuroinflammatory conditions. The incidence of central neuropathic pain differs based on its underlying cause.
Rosner, Jan+6 more
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AbstractBackground and purpose: Neuropathic pain (NP) is often refractory to pharmacologic and non-interventional treatment. Neuropathic pain can be distinguished from non-neuropathic pain by two factors. In neuropathic pain there is no transduction (conversion of a nociceptive stimulus into an electrical impulse).
Amanda, Macone, James A D, Otis
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Diagnosing neuropathic pain and distinguishing it from nociceptive pain can be challenging, but is essential because both forms of pain require different treatment strategies. The diagnosis of neuropathic pain is primarily based on clinical findings.
Janne, Gierthmühlen, Ralf, Baron
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A neuropathic pain scale is effective in identifying neuropathic pain. [PDF]
To explore the application value of a Neuropathic Pain Questionnaire (NPQ) in screening for neuropathic pain (NP).Using a prospective study approach, patients with chronic pain treated and hospitalized in Quanzhou First Hospital between September 2020 and December 2023 were chosen as study subjects. Participants were screened using NPQ and then divided
Zhou J, Yao X, Zhao J, Li J.
europepmc +3 more sources
Single-Blind Placebo-Controlled Response Test with Phenytoin 10% Cream in Neuropathic Pain Patients
Background: Phenytoin cream applied topically has been explored in neuropathic pain conditions. In several case series, phenytoin 5% and 10% cream could reduce pain in a clinically relevant way with a fast onset of action within 30 min, and with positive
David J. Kopsky+1 more
doaj +1 more source
Analgesic effectiveness and tolerability of oral oxycodone/naloxone and pregabalin in patients with lung cancer and neuropathic pain. An observational analysis [PDF]
INTRODUCTION: Cancer-related pain has a severe negative impact on quality of life. Combination analgesic therapy with oxycodone and pregabalin is effective for treating neuropathic cancer pain.
Borghesi, Cristina+6 more
core +2 more sources
NEUROPATHIC PAIN AS A CHALLENGING CLINICAL ENTITY IN OLDER ADULTS
Neuropathic pain is a challenging clinical entity in older adults. Certain clinical conditions such as diabetes mellitus, cerebrovascular diseases and infections may lead to neuropathic pain in the elderly.
Ilke Coskun Benlidayi
doaj +1 more source
Key Clinical Message Acute paraplegia after treatment with intrathecal methotrexate requires a complete spinal cord neuroimaging as well as electrodiagnostic examination.
Carmen Montejo+4 more
doaj +1 more source