Statistical Applications in Pain Management: A Review [PDF]
arXiv, 2023 Chronic pain is a widespread and debilitating condition that affects millions of individuals worldwide. Recent research has unveiled a connection between chronic pain and epigenetic processes, shedding light on the complex interplay between genetics, environment, and pain perception.
arxiv
Multicenter assessment of quantitative sensory testing (QST) for the detection of neuropathic-like pain responses using the topical capsaicin model [PDF]
, 2018 Background: The use of quantitative sensory testing (QST) in multicenter studies has been quite limited, due in part to lack of standardized procedures among centers. Aim: The aim of this study was to assess the application of the capsaicin pain model
Bushnell, M. Catherine +13 more
core +1 more source
Microfluidic Spinning of PEDOT:PSS Microfibers for Nerve Guidance Conduits
Advanced Materials Technologies, EarlyView.This publication explores the fabrication of microfluidically spun PEDOT:PSS microfibers for conductive nerve guidance conduits (NGCs). It details the spinning process, fiber characterization, and biocompatibility assessment. The study highlights the fibers' mechanical and electrical properties, non‐cytotoxicity, and potential for nerve regeneration or
Matthias Geiger +8 more
wiley +1 more source
Automatic pain recognition from Blood Volume Pulse (BVP) signal using machine learning techniques [PDF]
arXiv, 2023 Physiological responses to pain have received increasing attention among researchers for developing an automated pain recognition sensing system. Though less explored, Blood Volume Pulse (BVP) is one of the candidate physiological measures that could help objective pain assessment. In this study, we applied machine learning techniques on BVP signals to
arxiv
Advanced Science, EarlyView.Annexin A3 (ANXA3) plays an endogenous protective role in endothelial dysfunction in sepsis by stabilizing the actin cytoskeleton, modulating cell permeability, and inhibiting pATF2/CD62E inflammatory signaling. Abstract Increased endothelial permeability and a dysregulated inflammatory response play key roles in organ damage in sepsis.
Manyu Xing +4 more
wiley +1 more source
Equine Pain Behavior Classification via Self-Supervised Disentangled Pose Representation [PDF]
arXiv, 2021 Timely detection of horse pain is important for equine welfare. Horses express pain through their facial and body behavior, but may hide signs of pain from unfamiliar human observers. In addition, collecting visual data with detailed annotation of horse behavior and pain state is both cumbersome and not scalable.
arxiv
Bidirectional association between disturbed sleep and neuropathic pain symptoms : a prospective cohort study in post-total joint replacement participants [PDF]
, 2017 Background Disturbed sleep is strongly correlated with chronic pain. The aim of this study was to examine the association between sleep disturbance and incident joint pain focusing on neuropathic-like pain symptoms.
Abhishek, Abhishek +8 more
core +2 more sources
MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer
Advanced Science, EarlyView.This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang +9 more
wiley +1 more source
Neuropathic Pain in Elderly Patients with Chronic Low Back Painand Effects of Pregabalin: A Preliminary Study [PDF]
Asian Spine Journal, 2015 Study DesignPreliminary study.PurposeTo assess the association of neuropathic pain with chronic low back pain (LBP) and the effect of pregabalin on neuropathic pain in the elderly.Overview of LiteratureOf those with chronic LBP, 37% were predominantly ...
Yoshihito Sakai +4 more
doaj +1 more source
Temporal changes in the expression of the translocator protein TSPO and the steroidogenic enzyme 5a-reductase in the dorsal spinal cord of animals with neuropathic pain: effects of progesterone administration [PDF]
, 2016 Neuropathic pain is a frequent complication of spinal cord injury (SCI), still refractory to conventional treatment. The presence and biological activity of steroidogenic regulatory proteins and enzymes in the spinal cord suggests that neurosteroids ...
Adler, Natalia Sol +6 more
core +2 more sources