Results 131 to 140 of about 2,199 (172)

Neuropathogenesis of AIDS

Molecular Medicine Today, 1996
Neurological disease directly attributable to HIV-1 infection (HIV dementia) is one of the most frequent disorders in persons with AIDS. HIV-1 dementia is associated with neuronal loss, but occurs in the absence of direct viral infection of neurons, suggesting that neurological damage occurs by an indirect mechanism.
S, Dewhurst, H A, Gelbard, S M, Fine
openaire   +2 more sources

Understanding Perspectives and Research Trends in Down Syndrome Neuropathogenesis: A Bibliometric Analysis

Journal of Intellectual Disabilities
Down syndrome (DS), characterised by compromised brain development and intellectual challenges, often manifests Alzheimer's disease (AD) -like symptoms. Utilising the Web of Science Core Collection (WOSCC) database from January 1, 2000, to July 31, 2023,
Sharida Fakurazi, King Hwa Ling, Pike See Cheah   +2 more
exaly   +2 more sources

Developments in HIV Neuropathogenesis

Current Pharmaceutical Design, 2006
Despite the fact that neurons are rarely infected by the human immunodeficiency virus (HIV), neuronal loss is common in patients with HIV infection, likely due to the effects of viral proteins and inflammatory mediators on these cells. Despite the widespread use of highly active antiretroviral therapy (HAART), at least in developed nations, cognitive ...
Jeffrey A, Rumbaugh, Avindra, Nath
openaire   +2 more sources

HERVs in Neuropathogenesis

Journal of Neuroimmune Pharmacology, 2010
In humans, exogenous retroviruses are known to cause immunodeficiency and neurological disease. While endogenous retroviruses are firmly established pathogens in other species, the human endogenous retroviruses (HERVs) may well be considered as emerging pathogens.
openaire   +3 more sources

Update on the Neuropathogenesis of Delirium

Dementia and Geriatric Cognitive Disorders, 1999
Delirium has been considered a syndrome of generalized dysfunction of higher cortical functions due to its breadth of symptoms and associated diffuse slowing on electroencephalogram. Advances in neuropsychiatry have revealed differences between brain regions, including the hemispheres, which may underlie the constellation of symptoms among different ...
openaire   +2 more sources

Delirium: Diagnosis, Neuropathogenesis, and Treatment

Journal of Psychiatric Practice, 2001
Delirium affects more than 2 million patients in the United States each year. The onset of delirium often occurs after hospitalization and in many cases is due to medications or procedures performed during the hospitalization. Unfortunately, delirium remains unrecognized in the majority of patients for several reasons.
G L, Clary, K R, Krishnan
openaire   +2 more sources

The neuropathogenesis of delirium

Aging Clinical and Experimental Research, 1997
Delirium is a common and serious complication of acute illness in people admitted to hospital. Recent evidence suggests that delirium is associated with an increased subsequent risk of developing dementia, although it is unclear whether delirium merely serves as a marker of a preexisting risk or whether it may of itself provoke or facilitate ...
openaire   +1 more source

The neuropathogenesis of delirium

Reviews in Clinical Gerontology, 2002
Delirium is a common disorder in ill older patients, characterized by a fluctuating disturbance of consciousness and changes in cognition that develop over a short period of time. Studies have shown that delirium is an independent predictor of increased length of hospital stay, and is associated with increased dependency and mortality, as well as being
openaire   +1 more source

Unravelling the neuropathogenesis of Japanese encephalitis

Transactions of the Royal Society of Tropical Medicine and Hygiene, 2007
Japanese encephalitis is a devastating disease that causes a frequently fatal encephalitis and is a major health problem throughout much of Asia. Mortality rates can be as high as 30%, with one-third of survivors suffering severe neurological sequelae.
Khin Saw Aye, Myint, Robert V, Gibbons, Guey Chuen, Perng, Tom, Solomon   +3 more
openaire   +2 more sources

Neuropathogenesis of Japanese Encephalitis Virus

Journal of Neurovirology, 2002
In the central nervous system, the Japanese encephalitis virus can replicate only in neurons. The mechanism of the type of neurotropism was analyzed. The susceptibility to Japanese encephalitis virus infection in the rat brain was closely associated with neuronal immaturity.
openaire   +2 more sources