Results 21 to 30 of about 7,477 (215)
The neuropathogenesis of AIDS [PDF]
Nature Reviews Immunology, 2005 HIV-associated dementia (HAD) is an important complication of the central nervous system in patients who are infected with HIV-1. Although the incidence of HAD has markedly decreased since it has become possible to effectively control viral replication in the blood by administering highly active antiretroviral therapy, a less severe form of HAD ...
González-Scarano, Francisco +1 more
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Characterization of HIV-1 Infection in Microglia-Containing Human Cerebral Organoids
Viruses, 2022 The achievement of an HIV cure is dependent on the eradication or permanent silencing of HIV-latent viral reservoirs, including the understudied central nervous system (CNS) reservoir. This requires a deep understanding of the molecular mechanisms of HIV’
Stephanie B. H. Gumbs +9 more
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The neuropathogenesis of highly pathogenic avian influenza H5Nx viruses in mammalian species including humans [PDF]
, 2023 Circulation of highly pathogenic avian influenza (HPAI) H5Nx viruses of the A/Goose/Guangdong/1/96 lineage in birds regularly causes infections of mammals, including humans.
Debby van Riel +9 more
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Viruses, 2020 Dengue is an arboviral disease caused by dengue virus (DENV), which is transmitted to humans by Aedes aegypti mosquitoes. Infection by DENV most commonly results in a mild flu-like illness; however, the disease has been increasingly associated with ...
Natália Salomão +9 more
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Elimination of False Positives Generated Through PCR Re-amplification of Differential Display cDNA
BioTechniques, 1998 Differential display (DD) is a powerful molecular tool that allows the identification and subsequent isolation of transcripts differentially expressed between biological samples, for example, between undifferentiated and differentiated cells, between ...
G. Miele +4 more
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Advances and new insights in the neuropathogenesis of dengue infection [PDF]
, 2015 Dengue virus (DENV) infects approximately 390 million persons every year in more than 100 countries. Reports of neurological complications are more frequently.
Marzia Puccioni-Sohler, Carolina Rosadas
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Viral Determinants of Virulence in Tick-Borne Flaviviruses
Viruses, 2018 Tick-borne flaviviruses have a global distribution and cause significant human disease, including encephalitis and hemorrhagic fever, and often result in neurologic sequelae.
Eliza M. Kellman +3 more
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Viruses, 2022 Combined in silico, in vitro, and in vivo comparative studies between isogenic-recombinant Mouse-Hepatitis-Virus-RSA59 and its proline deletion mutant, revealed a remarkable contribution of centrally located two consecutive prolines (PP) from Spike ...
Abass Alao Safiriyu +8 more
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Return of the Neurotropic Enteroviruses: Co-Opting Cellular Pathways for Infection
Viruses, 2021 Enteroviruses are among the most common human infectious agents. While infections are often mild, the severe neuropathogenesis associated with recent outbreaks of emerging non-polio enteroviruses, such as EV-A71 and EV-D68, highlights their continuing ...
Christine E. Peters, Jan E. Carette
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The role of catecholamines in HIV neuropathogenesis [PDF]
Brain Research, 2019 The success of anti-retroviral therapy has improved the quality of life and lifespan of HIV + individuals, transforming HIV infection into a chronic condition. These improvements have come with a cost, as chronic HIV infection and long-term therapy have resulted in the emergence of a number of new pathologies.
R, Nolan, P J, Gaskill
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