Results 41 to 50 of about 7,477 (215)

Functional Genomics and Immunologic Tools: The Impact of Viral and Host Genetic Variations on the Outcome of Zika Virus Infection

open access: yesViruses, 2018
Zika virus (ZIKV) causes no-to-mild symptoms or severe neurological disorders. To investigate the importance of viral and host genetic variations in determining ZIKV infection outcomes, we created three full-length infectious cDNA clones as bacterial ...
Sang-Im Yun   +8 more
doaj   +1 more source

Buprenorphine reverses neurocognitive impairment in EcoHIV infected mice: A potential therapy for HIV-NCI

open access: yesFrontiers in Immunology, 2022
Thirty-eight million people worldwide are living with HIV, PWH, a major public health problem. Antiretroviral therapy (ART) revolutionized HIV treatment and significantly increased the lifespan of PWH.
Aniella J. Murphy   +6 more
doaj   +1 more source

Feline Immunodeficiency Virus Neuropathogenesis: From Cats to Calcium

open access: yes, 2007
Invasion of human immunodeficiency virus (HIV) into the central and peripheral nervous system produces a wide range of neurological symptoms, which continue to persist even with adequate therapeutic suppression of the systemic viremia. The development of
Meeker, Rick B., Rick B. Meeker
core   +1 more source

SARS-CoV-2-Related Olfactory Dysfunction: Autopsy Findings, Histopathology, and Evaluation of Viral RNA and ACE2 Expression in Olfactory Bulbs

open access: yesBiomedicines
Background: The COVID-19 pandemic has been a health emergency with a significant impact on the world due to its high infectiousness. The disease, primarily identified in the lower respiratory tract, develops with numerous clinical symptoms affecting ...
Marco Dell’Aquila   +11 more
doaj   +1 more source

Global Gene Expression Analysis of the Brainstem in EV71- and CVA16-Infected Gerbils

open access: yesViruses, 2019
Enterovirus 71 (EV71) and coxsackievirus A16 (CVA16) are the two most important pathogens of hand, foot, and mouth disease (HFMD). However, the neuropathogenesis of EV71 and CVA16 has not been elucidated.
Yi-Sheng Sun   +8 more
doaj   +1 more source

Neuropathogenesis of naturally occurring encephalitis caused by Listeria monocytogenes in ruminants

open access: yes, 2010
Listeriosis is a serious food-borne disease with increasing frequency in humans and ruminants. Despite the facts that in both hosts, listeriosis can occur as rhombencephalitis and ruminants are a reservoir of Listeria monocytogenes (LM) strains ...
Zurbriggen, Andreas   +5 more
core   +1 more source

Neuropathogenesis of Human Rabies

open access: yesKESANS : International Journal of Health and Science, 2022
Rabies is an acute infection that occurs in the central nervous system caused by a virus from the Rhabdoviridae family and the Lyssavirus genus that can be transmitted by dogs, cats, monkeys, bats, civets, and wolves. The purpose of writing this literature review is to determine the definition, epidemiology, neuropathogenesis and the role of ...
Inas Hanan Farihah   +4 more
openaire   +2 more sources

Neural Stem Cells as Tools for Understanding Retroviral Neuropathogenesis

open access: yes, 2000
The discovery within the past decade that neural stem cells (NSCs) from the developing and adult mammalian brain can be propagated, cloned, and genetically manipulated ex vivo for ultimate transfer back into the CNS has opened the door to a novel means ...
Portis, John L., Lynch, William P.
core   +1 more source

Spread of Oropouche Virus into the Central Nervous System in Mouse

open access: yesViruses, 2014
Oropouche virus (OROV) is an important cause of arboviral illness in Brazil and other Latin American countries, with most cases clinically manifested as acute febrile illness referred to as Oropouche fever, including myalgia, headache, arthralgia and ...
Rodrigo I. Santos   +7 more
doaj   +1 more source

ZNF33B Promotes Japanese Encephalitis Virus Infection by Regulating the Stability of M6A‐Modified Trim25 to Control the Autophagy Process

open access: yesAdvanced Science, EarlyView.
Upon JEV infection, ZNF33B recruits METTL14 to stabilize the METTL3‐METTL14 m6A methyltransferase complex, leading to increased m6A modification of host transcripts, including Trim25 mRNA. ZNF33B selectively binds m6A‐modified sites on Trim25 mRNA and accelerates its decay, resulting in reduced TRIM25 protein abundance.
Jian Du   +9 more
wiley   +1 more source

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