Results 41 to 50 of about 8,002 (210)

Functional Genomics and Immunologic Tools: The Impact of Viral and Host Genetic Variations on the Outcome of Zika Virus Infection

open access: yesViruses, 2018
Zika virus (ZIKV) causes no-to-mild symptoms or severe neurological disorders. To investigate the importance of viral and host genetic variations in determining ZIKV infection outcomes, we created three full-length infectious cDNA clones as bacterial ...
Sang-Im Yun   +8 more
doaj   +1 more source

Age-Dependent Invasion of Pseudorabies Virus into Porcine Central Nervous System via Maxillary Nerve

open access: yesPathogens, 2022
Pseudorabies virus (PRV) is the causative agent for Aujeszky’s disease, a disease that mainly affects pigs and incidentally other domestic and wild animals.
Konstantinos Papageorgiou   +9 more
doaj   +1 more source

Maresin-like 1 Ameliorates Neuropathology of Alzheimer’s Disease in Brains of a Transgenic Mouse Model

open access: yesBiomedicines
(1) Background: Impeded resolution of inflammation contributes substantially to the pathogenesis of Alzheimer’s disease (AD); consequently, resolving inflammation is pivotal to the amelioration of AD pathology.
Pallavi Shrivastava   +8 more
doaj   +1 more source

Global Gene Expression Analysis of the Brainstem in EV71- and CVA16-Infected Gerbils

open access: yesViruses, 2019
Enterovirus 71 (EV71) and coxsackievirus A16 (CVA16) are the two most important pathogens of hand, foot, and mouth disease (HFMD). However, the neuropathogenesis of EV71 and CVA16 has not been elucidated.
Yi-Sheng Sun   +8 more
doaj   +1 more source

Buprenorphine reverses neurocognitive impairment in EcoHIV infected mice: A potential therapy for HIV-NCI

open access: yesFrontiers in Immunology, 2022
Thirty-eight million people worldwide are living with HIV, PWH, a major public health problem. Antiretroviral therapy (ART) revolutionized HIV treatment and significantly increased the lifespan of PWH.
Aniella J. Murphy   +6 more
doaj   +1 more source

Neuropathogenesis of Human Rabies

open access: yesKESANS : International Journal of Health and Science, 2022
Rabies is an acute infection that occurs in the central nervous system caused by a virus from the Rhabdoviridae family and the Lyssavirus genus that can be transmitted by dogs, cats, monkeys, bats, civets, and wolves. The purpose of writing this literature review is to determine the definition, epidemiology, neuropathogenesis and the role of ...
Inas Hanan Farihah   +4 more
openaire   +2 more sources

Spread of Oropouche Virus into the Central Nervous System in Mouse

open access: yesViruses, 2014
Oropouche virus (OROV) is an important cause of arboviral illness in Brazil and other Latin American countries, with most cases clinically manifested as acute febrile illness referred to as Oropouche fever, including myalgia, headache, arthralgia and ...
Rodrigo I. Santos   +7 more
doaj   +1 more source

RNF138‐Mediated Ubiquitination and Degradation of NS5 Restricts Tick‐Borne Encephalitis Virus Infection

open access: yesAdvanced Science, Volume 13, Issue 49, 3 September 2026.
Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun   +6 more
wiley   +1 more source

Nipah Virus Encephalitis: Pathogenetic Aspects and Current Therapeutic Strategies

open access: yesPathogens
Nipah virus (NiV) is a highly pathogenic zoonotic paramyxovirus responsible for sporadic outbreaks of severe disease with high case fatality rates in South and Southeast Asia.
Gaetano Scotto   +5 more
doaj   +1 more source

Apoptosis and HIV neuropathogenesis

open access: yesMedical Hypotheses, 1995
A consequence of HIV infection may be neurological dysfunction secondary to the presence of virus in the central nervous system (CNS). The CNS tropism of HIV and the mechanisms that govern its dissemination are not well defined. One view is that HIV enters the brain through the diapedesis of infected monocytes from blood into the perivascular space ...
openaire   +2 more sources

Home - About - Disclaimer - Privacy