Results 11 to 20 of about 2,199 (172)
Frontiers in Cellular and Infection Microbiology, 2019 Mosquito-borne flaviviruses can cause disease in the nervous system, resulting in a significant burden of morbidity and mortality. Disease models are necessary to understand neuropathogenesis and identify potential therapeutics and vaccines.
Megan Chesnut +10 more
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Zika Virus and Neuropathogenesis: The Unanswered Question of Which Strain Is More Prone to Causing Microcephaly and Other Neurological Defects [PDF]
Frontiers in Cellular Neuroscience, 2021 Despite being perceived to be a relatively innocuous pathogen during its circulation in Africa in the 20th century, consequent outbreaks in French Polynesia and Latin America revealed the Zika virus (ZIKV) to be capable of causing severe neurological ...
Emily Louise King, Nerea Irigoyen
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Role of EphrinA3 in HIV-1 Neuropathogenesis
ASN Neuro, 2021 Glial cells perform important supporting functions for neurons through a dynamic crosstalk. Neuron–glia communication is the major phenomenon to sustain homeostatic functioning of the brain. Several interactive pathways between neurons and astrocytes are
Chitra Mohinder Singh Singal +4 more
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The neuropathogenesis of HIV-1 infection
Journal of Leukocyte Biology, 1994 HIV infection in brain revolves around productive viral replication in cells of mononuclear phagocyte lineage, including brain macrophages, microglia, and multinucleated giant cells [1–4].
Stuart A Lipton +4 more
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The neuropathogenesis of AIDS [PDF]
Nature Reviews Immunology, 2005 HIV-associated dementia (HAD) is an important complication of the central nervous system in patients who are infected with HIV-1. Although the incidence of HAD has markedly decreased since it has become possible to effectively control viral replication in the blood by administering highly active antiretroviral therapy, a less severe form of HAD ...
González-Scarano, Francisco +1 more
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The neuropathogenesis of highly pathogenic avian influenza H5Nx viruses in mammalian species including humans [PDF]
, 2023 Circulation of highly pathogenic avian influenza (HPAI) H5Nx viruses of the A/Goose/Guangdong/1/96 lineage in birds regularly causes infections of mammals, including humans.
Debby van Riel +9 more
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Advances and new insights in the neuropathogenesis of dengue infection [PDF]
, 2015 Dengue virus (DENV) infects approximately 390 million persons every year in more than 100 countries. Reports of neurological complications are more frequently.
Marzia Puccioni-Sohler +3 more
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Highly efficient method for gene delivery in mouse dorsal root ganglia neurons
Frontiers in Molecular Neuroscience, 2015 The development of gene transfection technologies has greatly advanced our understanding of life sciences. While use of viral vectors has clear efficacy, it requires specific expertise and biological containment conditions.
Lingli eYu +19 more
doaj +1 more source
Viral Determinants of Virulence in Tick-Borne Flaviviruses
Viruses, 2018 Tick-borne flaviviruses have a global distribution and cause significant human disease, including encephalitis and hemorrhagic fever, and often result in neurologic sequelae.
Eliza M. Kellman +3 more
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Henipavirus-induced neuropathogenesis in mice
Virology, 2023 Hendra virus (HeV) and Nipah virus (NiV) are henipaviruses that can cause fatal encephalitis in humans. Many animal models have been used to study henipavirus pathogenesis. In the mouse, HeV infection has previously shown that intranasal challenge can lead to neurological infection, however mice similarly challenged with NiV show no evidence of virus ...
Sarah J. Edwards +8 more
openaire +2 more sources