Results 41 to 50 of about 1,609 (181)

Modelling West Nile Virus and Usutu Virus Pathogenicity in Human Neural Stem Cells

Viruses, 2020
West Nile virus (WNV) and Usutu virus (USUV) are genetically related neurotropic mosquito-borne flaviviruses, which frequently co-circulate in nature. Despite USUV seeming to be less pathogenic for humans than WNV, the clinical manifestations induced by ...
Silvia Riccetti, Alessandro Sinigaglia, Giovanna Desole, Norbert Nowotny, Marta Trevisan, Luisa Barzon   +5 more
doaj   +1 more source

Tissue-specific expansion of Zika virus isogenic variants drive disease pathogenesisResearch in context

EBioMedicine, 2023
Summary: Background: The Asian lineage Zika virus (ZIKV) emerged as a public health emergency in 2016 causing severe neurological pathologies with no apparent historical correlate to the mild, disease-causing innocuous member of the mosquito-borne ...
Kitti Wing Ki Chan, Amanda Makha Bifani, Satoru Watanabe, Milly M. Choy, Eng Eong Ooi, Subhash G. Vasudevan   +5 more
doaj   +1 more source

Broad AOX expression in a genetically tractable mouse model does not disturb normal physiology [PDF]

, 2016
Plants and many lower organisms, but not mammals, express alternative oxidases (AOXs) that branch the mitochondrial respiratory chain, transferring electrons directly from ubiquinol to oxygen without proton pumping.
Braun, Thomas, de Angelis, Martin Hrabe, Dhandapani, Praveen K., Dufour, Eric, Fuchs, Helmut, Gailus-Durner, Valerie, Gainutdinov, Timur, Gellerich, Frank N., German Mouse Clinic Consortium, Gizatullina, Zemfira, Heidler, Juliana, Holmstrom, Kira M., Jacobs, Howard T., Nandania, Jatin, Rustin, Pierre, Salwig, Isabelle, Szibor, Marten, Velagapudi, Vidya, Wietelmann, Astrid, Wittig, Ilka, Zhuang, Yuan   +20 more
core   +2 more sources

Differences in neuroinvasion and protective innate immune pathways between encephalitic California Serogroup orthobunyaviruses.

PLoS Pathogens, 2022
The California serogroup (CSG) of Orthobunyaviruses comprises several members capable of causing neuroinvasive disease in humans, including La Crosse orthobunyavirus (LACV), Jamestown Canyon orthobunyavirus (JCV), and Inkoo orthobunyavirus (INKV ...
Alyssa B Evans, Clayton W Winkler, Karin E Peterson   +2 more
doaj   +1 more source

Equine herpesvirus type 1 infection induces procoagulant activity in equine monocytes [PDF]

, 2013
The alphaherpesvirus, equine herpesvirus type 1 (EHV-1), is a highly prevalent cause of equine infectious abortion and encephalomyelopathy. These syndromes have been attributed to ischemic necrosis from thrombosis in placental and neural vessels ...
Osterrieder, Nikolaus, Stokol, Tracy, Yeo, Wee Ming   +2 more
core   +2 more sources

Pathogenesis and amelioration of nontyphoidal Salmonella encephalopathy in cattle infected with Salmonella enterica serovar Saintpaul [PDF]

, 2011
Salmonella enterica serovar Saintpaul (SstpNPG) is a unique isolate capable of producing bovine encephalopathy in the presence of host neuroendocrine hormones.
Xiong, Nalee
core   +3 more sources

Post-COVID-19 Neuronal Complications and Impact of Physical Activity on the Disease Symptoms: A Narrative Review

Central European Journal of Sport Sciences and Medicine
The coronavirus disease 2019 (COVID-19) caused a global health crisis, leading to many pathological alternations regarding cells, tissues, organs, and biological systems.
Ewa Duchnik, Joanna Kruk, Mariola Marchlewicz   +2 more
doaj   +1 more source

Long term stability and infectivity of herpesviruses in water [PDF]

, 2017
For viruses to utilize environmental vectors (hard surfaces, soil, water) for transmission, physical and chemical stability is a prerequisite. There are many factors including pH, salinity, temperature, and turbidity that are known to contribute to the ...
Bischofberger, Sebastian, Damiani, Armando M., Dayaram, Anisha, Franz, Mathias, Greenwood, Alex D., Osterrieder, Nikolaus, Schattschneider, Alexander   +6 more
core   +2 more sources

Understanding Enterovirus D68-Induced Neurologic Disease: A Basic Science Review

Viruses, 2019
In 2014, the United States (US) experienced an unprecedented epidemic of enterovirus D68 (EV-D68)-induced respiratory disease that was temporally associated with the emergence of acute flaccid myelitis (AFM), a paralytic disease occurring predominantly ...
Alison M. Hixon, Joshua Frost, Michael J. Rudy, Kevin Messacar, Penny Clarke, Kenneth L. Tyler   +5 more
doaj   +1 more source

Differential replication of pathogenic and nonpathogenic strains of West Nile virus within astrocytes [PDF]

, 2012
The severity of West Nile virus (WNV) infection in immunocompetent animals is highly strain dependent, ranging from avirulent to highly neuropathogenic.
Diamond, Michael S, Fredericksen, Brenda L, Hussmann, Katherine L, Kim, Kwang S, Samuel, Melanie A   +4 more
core   +2 more sources