Results 21 to 30 of about 423,580 (268)

Diabetic Neuropathy: A Position Statement by the American Diabetes Association

Diabetes Care, 2016
Diabetic neuropathies are the most prevalent chronic complications of diabetes. This heterogeneous group of conditions affects different parts of the nervous system and presents with diverse clinical manifestations.
R. Pop-Busui, A. Boulton, E. Feldman, V. Bril, R. Freeman, R. Malik, J. Sosenko, D. Ziegler   +7 more
semanticscholar   +1 more source

Formulated Curcumin Prevents Paclitaxel-Induced Peripheral Neuropathy through Reduction in Neuroinflammation by Modulation of α7 Nicotinic Acetylcholine Receptors

Pharmaceutics, 2022
Paclitaxel is widely used in the treatment of various types of solid malignancies. Paclitaxel-induced peripheral neuropathy (PIPN) is often characterized by burning pain, cold, and mechanical allodynia in patients.
Martial Caillaud, Danielle Thompson, Wisam Toma, Alyssa White, Jared Mann, Jane L. Roberts, John W. Bigbee, David A. Gewirtz, M. Imad Damaj   +8 more
doaj   +1 more source

Trench Foot or Non-Freezing Cold Injury As a Painful Vaso-Neuropathy: Clinical and Skin Biopsy Assessments

Frontiers in Neurology, 2017
BackgroundTrench foot, or non-freezing cold injury (NFCI), results from cold exposure of sufficient severity and duration above freezing point, with consequent sensory and vascular abnormalities which may persist for years.
Praveen Anand, Rosario Privitera, Yiangos Yiangou, Philippe Donatien, Rolfe Birch, Peter Misra   +5 more
doaj   +1 more source

Peripheral neuropathy

Journal of Neurology, 2019
Peripheral neuropathies are common in neurological practice, but it is also tue that they are common in many other medical and surgical fields. There are hundreds and thousands causes of peripheral neuropathies, and a variety of clinical manifestations ...
Lisa M. Shulman, Paul Dash, Nicole Villemarette-Pittman, Robert G. Miller, D F Gelinas, Patricia O’Connor, E. Leppik, Joel S. Steinberg, William B. Young, Stephen D. Silberstein, Wayne A. Henning, C. Kushida   +11 more
semanticscholar   +1 more source

Upregulation of microRNA 344a-3p is involved in curcumin induced apoptosis in RT4 schwannoma cells

Cancer Cell International, 2018
Background Schwannoma arising from peripheral nervous sheaths is a benign tumor. Methods To evaluate cell cytotoxicity, (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) tetrazolium reduction and terminal deoxynucleotidyltransferase UTP nick-
Eun Jung Sohn, Kyoung-mi Bak, Yun-kyeong Nam, Hwan Tae Park   +3 more
doaj   +1 more source

Kaurenoic Acid Reduces Ongoing Chronic Constriction Injury-Induced Neuropathic Pain: Nitric Oxide Silencing of Dorsal Root Ganglia Neurons

Pharmaceuticals, 2023
Kaurenoic acid (KA) is a diterpene extracted from Sphagneticola trilobata (L.) Pruski. KA presents analgesic properties. However, the analgesic activity and mechanisms of action of KA in neuropathic pain have not been investigated so far; thus, we ...
Tiago H. Zaninelli, Sandra S. Mizokami, Mariana M. Bertozzi, Telma Saraiva-Santos, Felipe A. Pinho-Ribeiro, Gabriele Inácio de Oliveira, Renata Streck, Eduardo J. A. Araújo, Nilton S. Arakawa, Sergio M. Borghi, Rubia Casagrande, Waldiceu A. Verri   +11 more
doaj   +1 more source

Mechanisms of Chemotherapy-Induced Peripheral Neuropathy

International Journal of Molecular Sciences, 2019
Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most frequent side effects caused by antineoplastic agents, with a prevalence from 19% to over 85%.
R. Zajączkowska, M. Kocot-Kępska, W. Leppert, A. Wrzosek, J. Mika, J. Wordliczek   +5 more
semanticscholar   +1 more source

[Ru(bpy)2(NO)SO3](PF6), a Nitric Oxide Donating Ruthenium Complex, Reduces Gout Arthritis in Mice

Frontiers in Pharmacology, 2019
Monosodium urate crystals (MSU) deposition induces articular inflammation known as gout. This disease is characterized by intense articular inflammation and pain by mechanisms involving the activation of the transcription factor NFκB and inflammasome ...
Ana C. Rossaneis, Daniela T. Longhi-Balbinot, Mariana M. Bertozzi, Victor Fattori, Carina Z. Segato-Vendrameto, Stephanie Badaro-Garcia, Tiago H. Zaninelli, Larissa Staurengo-Ferrari, Sergio M. Borghi, Thacyana T. Carvalho, Allan J. C. Bussmann, Florêncio S. Gouveia, Luiz G. F. Lopes, Rubia Casagrande, Waldiceu A. Verri   +14 more
doaj   +1 more source

A Novel Model of Cancer-Induced Peripheral Neuropathy and the Role of TRPA1 in Pain Transduction [PDF]

Pain Research and Management, Volume 2017, Article ID 3517207, 2018
Background. Models of cancer-induced neuropathy are designed by injecting cancer cells near the peripheral nerves. The interference of tissue-resident immune cells does not allow a direct contact with nerve fibres which affects the tumor microenvironment and the invasion process. Methods.
arxiv   +1 more source

Understanding Diabetic Neuropathy: Focus on Oxidative Stress

Oxidative Medicine and Cellular Longevity, 2020
Diabetic neuropathy is one of the clinical syndromes characterized by pain and substantial morbidity primarily due to a lesion of the somatosensory nervous system.
L. Pang, Xin Lian, Huanqiu Liu, Yuan Zhang, Qian Li, Yin Cai, Haichun Ma, Xin Yu   +7 more
semanticscholar   +1 more source