Results 41 to 50 of about 204,831 (332)

The endogenous neuropeptide calcitonin gene-related peptide after spontaneous subarachnoid hemorrhage–A potential psychoactive prognostic serum biomarker of pain-associated neuropsychological symptoms

Frontiers in Neurology, 2022
BackgroundThe pronociceptive neuromediator calcitonin gene-related peptide (CGRP) is associated with pain transmission and modulation. After spontaneous subarachnoid hemorrhage (sSAH), the vasodilatory CGRP is excessively released into cerebrospinal ...
Elisabeth Bründl, Martin Proescholdt, Eva-Maria Störr, Petra Schödel, Sylvia Bele, Florian Zeman, Christoph Hohenberger, Martin Kieninger, Nils Ole Schmidt, Karl-Michael Schebesch   +9 more
doaj   +1 more source

Global parameter search reveals design principles of the mammalian circadian clock [PDF]

, 2008
Background: Virtually all living organisms have evolved a circadian (~24 hour) clock that controls physiological and behavioural processes with exquisite precision throughout the day/night cycle.
AC Liu, Achim Kramer, AT Winfree, BC Goodwin, D Gonze, D Somers, DB Forger, DB Forger, DK Welsh, ES Maywood, H Albus, H Kunz, Hanspeter Herzel, HD Piggins, James CW Locke, JC Dunlap, JC Leloup, JCW Locke, JCW Locke, JD Best, JE Quintero, JP Wisor, JS Griffith, K Vanselow, M Gallego, M Nagano, MC Antle, MH Hastings, MY Cheng, P Achermann, Pål O Westermark, RA Prosser, S Becker-Weimann, S Bernard, S Bornholdt, S Honma, S Yamazaki, SH Strogatz, SH Strogatz, SJ Aton, SJ Aton, SJ Kuhlman, TL To, VK Gribkoff, VM King, W Nakamura, Y Shigeyoshi   +46 more
core   +5 more sources

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Role of the bed nucleus of the stria terminalis in feeding

Frontiers in Nutrition
As an important part of the limbic system of the forebrain, the bed nucleus of the stria terminalis (BNST) plays a key role in stress response, emotion regulation, and motivational behavior. Recent studies have demonstrated that BNST plays a crucial role
Keyan Wang, Wenbo Guo, Jiaxiang Xu, Yingjie Kuang, Xiqi Chen   +4 more
doaj   +1 more source

Identifying functional populations among the interneurons in laminae I-III of the spinal dorsal horn [PDF]

, 2017
The spinal dorsal horn receives input from primary afferent axons, which terminate in a modality-specific fashion in different laminae. The incoming somatosensory information is processed through complex synaptic circuits involving excitatory and ...
Todd, Andrew J.
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Anti-diuretic hormone ITP signals via a guanylate cyclase receptor to modulate systemic homeostasis in Drosophila

eLife
Insects have evolved a variety of neurohormones that enable them to maintain nutrient and osmotic homeostasis. Here, we characterized the ion transport peptide (ITP) signaling system in Drosophila.
Jayati Gera, Marishia Agard, Hannah Nave, Austin B Baldridge, Farwa Sajadi, Leena Thorat, Theresa H McKim, Shu Kondo, Dick R Nässel, Mitchell H Omar, Jean-Paul Paluzzi, Meet Zandawala   +11 more
doaj   +1 more source

Males, the Wrongly Neglected Partners of the Biologically Unprecedented Male–Female Interaction of Schistosomes

Frontiers in Genetics, 2019
Schistosomes are the only platyhelminths that have evolved separate sexes, and they exhibit a unique reproductive biology because the female’s sexual maturation depends on a constant pairing contact with the male.
Zhigang Lu, Zhigang Lu, Sebastian Spänig, Oliver Weth, Christoph G. Grevelding   +4 more
doaj   +1 more source

Neuroendocrine regulations in tissue-specific immunity: From mechanism to applications in tumor

Frontiers in Cell and Developmental Biology, 2022
Immune responses in nonlymphoid tissues play a vital role in the maintenance of homeostasis. Lots of evidence supports that tissue-specific immune cells provide defense against tumor through the localization in different tissue throughout the body, and ...
Si-Qing Liu, Bei Li, Juan-Juan Li, Si Sun, Sheng-Rong Sun, Qi Wu   +5 more
doaj   +1 more source

Identification and Characterization of the Corazonin Receptor and Possible Physiological Roles of the Corazonin-Signaling Pathway in Rhodnius prolixus. [PDF]

, 2016
Neuropeptides control many physiological and endocrinological processes in animals, acting as neuroactive chemicals within the central and peripheral nervous systems.
Hamoudi, Zina, Lange, Angela B, Orchard, Ian   +2 more
core   +2 more sources