Results 151 to 160 of about 9,276,761 (294)

Progress on the development of Class A GPCR‐biased ligands

British Journal of Pharmacology, EarlyView.
Class A G protein‐coupled receptors (GPCRs) continue to garner interest for their essential roles in cell signalling and their importance as drug targets. Although numerous drugs in the clinic target these receptors, over 60% GPCRs remain unexploited. Moreover, the adverse effects triggered by the available unbiased GPCR modulators, limit their use and
Paula Morales, Magdalena M. Scharf, Marcel Bermudez, Attila Egyed, Rafael Franco, Olivia K. Hansen, Nadine Jagerovic, Jan Jakubík, György M. Keserű, Dóra Judit Kiss, Pawel Kozielewicz, Olav Larsen, Maria Majellaro, Ana Mallo‐Abreu, Gemma Navarro, Rubén Prieto‐Díaz, Mette M. Rosenkilde, Eddy Sotelo, Holger Stark, Tobias Werner, Laura M. Wingler   +20 more
wiley   +1 more source

Neuropeptide Y Regulates Sleep by Modulating Noradrenergic Signaling

Current Biology, 2017

semanticscholar   +1 more source

Somatostatin-, vasoactive intestinal polypeptide- and neuropeptide Y-like immunoreactivity in eye- and submandibular gland-projecting sympathetic neurons

, 1989
Linda L. Wright, Jennifer I. Luebke
openalex   +1 more source

Inhibition of neuropeptide Y‐induced potentiation of noradrenaline‐induced vasoconstriction by PP56 (d‐myo‐inositol 1,2,6‐tris‐phosphate) [PDF]

, 1992
M. Adamsson, Bo Fallgren, Lars Edvinsson
openalex   +1 more source

Characterisation of neurogenic lipolytic responses in white adipose tissue ex vivo

British Journal of Pharmacology, Volume 182, Issue 9, Page 1975-1988, May 2025.
Background and Purpose Dysfunction of the autonomic nervous system is associated with cardiovascular dysfunction, including metabolic syndrome and obesity. Understanding mechanisms of neurogenic control of white adipose tissue is key to understanding adipose physiology and pathophysiology, though there is limited research exploring this in adipose ...
Kayleigh E. Goddard, Samuel J. Fountain
wiley   +1 more source

Current views on neuropeptide Y and diabetes-related atherosclerosis

Diabetes & vascular disease research, 2017
Weiwei Sun, Ping Zhu, Yanchuan Shi, Chen-liang Zhang, Xu-Feng Huang, Shi-yu Liang, Zhi-Yuan Song, Shu Lin   +7 more
semanticscholar   +1 more source

Effects of neuropeptide Y and agonists selective for neuropeptide Y receptor sub‐types on arterioles of the guinea‐pig small intestine and the rat brain [PDF]

, 1992
Jun Xia, T O Neild, Neela Kotecha
openalex   +1 more source

Cannabidiol dose dependently reduces alcohol intake in mice via a non‐5‐HT1A receptor mechanism: Exploration of other potential receptor targets

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Binge drinking is a risky pattern of alcohol intake and a major predictor of alcohol use disorder (AUD). Current AUD medications have limited efficacy and poor patient compliance, calling for more effective therapeutics.
Connie J. Badolato, Erin A. Lynch, Jonathon C. Arnold, Iain S. McGregor, Michael T. Bowen   +4 more
wiley   +1 more source

Isolation and structure of the second of two major peptide products from the precursor to an anglerfish peptide homologous to neuropeptide Y.

, 1986
Philip Andrews, Jack E. Dixon
openalex   +1 more source

Functional effects and ligand binding of chimeric galanin‐neuropeptide Y (NPY) peptides on NPY and galanin receptor types [PDF]

, 1994
Ulrika Kahl, Ülo Langel, Tamás Bartfai, Lars Grundemar   +3 more
openalex   +1 more source