Results 191 to 200 of about 9,276,761 (294)
Estrogen synthesized in the central nervous system enhances MC4R expression and reduces food intake
Estrogen is regulated by the rate‐limiting enzyme aromatase. This study examines how neuroestrogens, estrogen produced in the brain, regulate appetite through the hypothalamus. Using ovariectomized, aromatase knockout, and brain‐specific aromatase‐restored mice, the study found that neuroestrogens suppress appetite by influencing genes like Mc4r.
Takanori Hayashi+8 more
wiley +1 more source
Limbic substrates of the effects of neuropeptide Y on intake of and motivation for palatable food
R. Pandit+4 more
semanticscholar +1 more source
Steroidal regulation of hypothalamic neuropeptide Y release and gene expression
Anita Sahu
openalex +1 more source
Abstract Background The Trial of External trigeminal nerve stimulation (eTNS) for the Acute treatment of Migraine (TEAM) study demonstrated that eTNS use during active migraine resulted in significantly higher rates of resolution of migraine‐associated most bothersome symptom (MBS) compared to sham.
Gregory A. Panza+2 more
wiley +1 more source
Abstract Background Serum 25‐hydroxyvitamin D (25[OH]D) concentrations have been shown to be low in patients with migraine, but results are controversial regarding the current role of vitamin D in migraine severity. Using a case–control design, we aimed to evaluate serum 25(OH)D levels in a group of females with high‐frequency episodic migraine/chronic
Marina Haro+6 more
wiley +1 more source
Abstract Objective This study aimed to provide proof‐of‐concept that multi‐receptor antagonist peptides can be generated by covalently linking independent antagonist peptides that block calcitonin gene‐related peptide (CGRP8‐37) or pituitary adenylate cyclase‐activating peptide (PACAP)/vasoactive intestinal peptide (VIP) (PACAP6‐38) activity ...
Zoe Tasma+5 more
wiley +1 more source
Abstract Objectives/Background This study was undertaken to evaluate the postmarketing safety of monoclonal antibodies (mAbs) targeting the calcitonin gene‐related peptide pathway used for migraine prophylaxis through pharmacovigilance data analysis by examining suspected adverse events reported in Europe.
Victoria Nikitina+3 more
wiley +1 more source
Targeting the neuropeptide Y system in stress-related psychiatric disorders
N. Enman+3 more
semanticscholar +1 more source
Depressor Effect of Intrathecal Neuropeptide Y (NPY) Is Mediated by Y2 Subtype of NPY Receptors
Xiaoli Chen, Thomas C. Westfall
openalex +1 more source